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Gender-specific cephalometric features related to obesity in sleep apnea patients: trilogy of soft palate-mandible-hyoid bone

  • Cho, Seok Hyun (Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Hanyang University) ;
  • Jeon, Jae-Yun (Department of Dentistry/Oral and Maxillofacial Surgery, School of Medicine, Hanyang University) ;
  • Jang, Kun-Soo (Department of Dentistry/Oral and Maxillofacial Surgery, School of Medicine, Hanyang University) ;
  • Kim, Sang Yoon (Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Harvard Medical School) ;
  • Kim, Kyung Rae (Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Hanyang University) ;
  • Ryu, Seungho (Department of Occupational Medicine, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University) ;
  • Hwang, Kyung-Gyun (Department of Dentistry/Oral and Maxillofacial Surgery, School of Medicine, Hanyang University)
  • Received : 2019.01.17
  • Accepted : 2019.11.27
  • Published : 2019.12.31

Abstract

Background: The aim of this study is to investigate the relationship between gender-specific and obesity-related airway anatomy in patients with obstructive sleep apnea (OSA) by using cephalometric analyses. Methods: We retrospectively evaluated 206 patients with suspected OSA undergoing polysomnography and anthropometric measurements such as body mass index, neck circumference, and waist-hip ratio. We checked lateral cephalometry to measure tissue landmarks including angle from A point to nasion to B point (ANB), soft palate length (SPL), soft palate thickness (SPT), retropalatal space (RPS), retrolingual space (RLS), and mandibular plane to hyoid (MPH). Results: Male with OSA showed significantly increased SPL (P = .006) compared with controls. SPL and MPH had significant correlation with apnea-hypopnea index (AHI) and central obesity. Female with OSA showed significantly increased ANB (P = .013) and SPT (P = .004) compared with controls. The receiver operating characteristic curves revealed that SPT in male and ANB and SPT in female were significant in model 1 (AHI ≥ 5) and model 2 (AHI ≥ 15). MPH was also significant for male in model 2. Conclusion: Male and female with OSA had distinct anatomic features of the upper airway and different interactions among soft palate, mandible, and hyoid bone.

Keywords

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