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Perampanel is also a useful adjunctive treatment option in refractory epilepsy in children

  • Kim, Jon Soo (Department of Pediatrics, Chungbuk National University Hospital) ;
  • Kim, Won Seop (Department of Pediatrics, Chungbuk National University Hospital)
  • Received : 2019.01.31
  • Accepted : 2019.03.05
  • Published : 2019.07.15

Abstract

Keywords

References

  1. Kwan P, Brodie MJ. Early identification of refractory epilepsy. N Engl J Med 2000;342:314-9. https://doi.org/10.1056/NEJM200002033420503
  2. Lin KL, Lin JJ, Chou ML, Hung PC, Hsieh MY, Chou IJ, et al. Efficacy and tolerability of perampanel in children and adolescents with pharmacoresistant epilepsy: the first real-world evaluation in Asian pediatric neurology clinics. Epilepsy Behav 2018;85:188-94. https://doi.org/10.1016/j.yebeh.2018.06.033
  3. Tsai JJ, Wu T, Leung H, Desudchit T, Tiamkao S, Lim KS, et al. Perampanel, an AMPA receptor antagonist: from clinical research to practice in clinical settings. Acta Neurol Scand 2018;137:378-91. https://doi.org/10.1111/ane.12879
  4. Steinhoff BJ, Ben-Menachem E, Ryvlin P, Shorvon S, Kramer L, Satlin A, et al. Efficacy and safety of adjunctive perampanel for the treatment of refractory partial seizures: a pooled analysis of three phase III studies. Epilepsia 2013;54:1481-9. https://doi.org/10.1111/epi.12212
  5. French JA, Krauss GL, Wechsler RT, Wang XF, DiVentura B, Brandt C, et al. Perampanel for tonic-clonic seizures in idiopathic generalized epilepsy A randomized trial. Neurology 2015;85:950-7. https://doi.org/10.1212/WNL.0000000000001930
  6. Yun Y, Kim D, Lee YJ, Kwon S, Hwang SK. Efficacy and tolerability of adjunctive perampanel treatment in children under 12 years of age with refractory epilepsy. Korean J Pediatr 2018 Dec 26 [Epub]. https://doi.org/10.3345/kjp.2018.06863.
  7. Biro A, Stephani U, Tarallo T, Bast T, Schlachter K, Fleger M, et al. Effectiveness and tolerability of perampanel in children and adolescents with refractory epilepsies: first experiences. Neuropediatrics 2015;46:110-6. https://doi.org/10.1055/s-0035-1546276
  8. De Liso P, Vigevano F, Specchio N, De Palma L, Bonanni P, Osanni E, et al. Effectiveness and tolerability of perampanel in children and adolescents with refractory epilepsies-An Italian observational multicenter study. Epilepsy Res 2016;127:93-100. https://doi.org/10.1016/j.eplepsyres.2016.08.021
  9. Heyman E, Lahat E, Levin N, Epstein O, Lazinger M, Berkovitch M, et al. Tolerability and efficacy of perampanel in children with refractory epilepsy. Dev Med Child Neurol 2017;59:441-4. https://doi.org/10.1111/dmcn.13362