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Bronchopulmonary dysplasia: how can we improve its outcomes?

  • Sung, Tae-Jung (Department of Pediatrics, Hallym University Medical Center)
  • 투고 : 2019.02.19
  • 심사 : 2019.05.17
  • 발행 : 2019.10.15

초록

Bronchopulmonary dysplasia (BPD) is a chronic lung disease of preterm infants with multiple factors affected from prenatal to postnatal periods. Despite significant advances in neonatal care over almost 50 years, BPD rates have not decreased; in fact, they may have even increased. Since more preterm infants, even at periviable gestational age, survive today, different stages of lung development affect the pathogenesis of BPD. Hence, the definition of BPD has changed from "old" to "new." In this review, we discuss the various definitions of BPD, risk factors from the prenatal to postnatal periods, management strategies by phase, and future directions for research.

키워드

참고문헌

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피인용 문헌

  1. Strategies to improve outcomes of bronchopulmonary dysplasia vol.62, pp.10, 2019, https://doi.org/10.3345/kjp.2019.00661
  2. Mechanism of oxidative stress and Keap-1/Nrf2 signaling pathway in bronchopulmonary dysplasia vol.99, pp.26, 2019, https://doi.org/10.1097/md.0000000000020433
  3. Comparisons of two definitions of bronchopulmonary dysplasia for the premature infants vol.57, pp.1, 2019, https://doi.org/10.1002/ppul.25739