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A Review on Clinical Studies of Acupuncture Treatment for Breast Cancer-Related Lymphedema

유방암 환자의 이차성 림프부종에 대한 침 치료 임상 연구 고찰

  • Park, Kyung-Dug (Dept. of Korean Medicine Obstetrics and Gynecology, School of Korean Medicine, Pusan National University) ;
  • Hwang, Su-In (Dept. of Korean Medicine Obstetrics and Gynecology, School of Korean Medicine, Pusan National University) ;
  • Park, Jang-Kyung (Dept. of Korean Medicine Obstetrics and Gynecology, School of Korean Medicine, Pusan National University) ;
  • Yoon, Young-Jin (Dept. of Korean Medicine Obstetrics and Gynecology, School of Korean Medicine, Pusan National University)
  • 박경덕 (부산대학교 한방병원 한방부인과) ;
  • 황수인 (부산대학교 한방병원 한방부인과) ;
  • 박장경 (부산대학교 한방병원 한방부인과) ;
  • 윤영진 (부산대학교 한방병원 한방부인과)
  • Received : 2019.07.09
  • Accepted : 2019.08.29
  • Published : 2019.08.30

Abstract

Objectives: The purpose of this study is to confirm the effectiveness and safety of acupuncture for treating breast cancer-related lymphedema (BCRL), thus providing a clinical basis for acupuncture treatment and helping to develop clinical practice guideline through consideration of used meridians and acupoints. Methods: Clinical studies applying acupuncture on breast cancer-related lymphedema were searched through 7 databases such as The Cochrane Library Central, Embase, Pubmed and CAJ. Interventions and results of the selected clinical studies were analyzed. Results: 8 Clinical studies were finally included according to inclusion and exclusion criteria. There were 6 randomized controlled studies and 2 single-arm pilot studies. All of those studies were searched in The Cochrane Library Central, Embase, Pubmed and CAJ and written in English and Chinese. Treatment group applied acupuncture as a Korean medicine intervention. Interventions of control group were made with non-treatment, upper limb exercise, and oral administration of capillary stabilizer or diuretics. Outcome measurements varied from paper to paper but every study measured reduction in arm circumference. Among 8 studies, 6 studies reported statistically significant reduction in arm circumference in treatment group and there were no serious adverse effects. Conclusions: This study suggested that acupuncture has few side effects as well as statistically significant effects on many aspects in treating breast cancer-related lymphedema. However the results should be taken cautiously as more clinical studies are needed.

Keywords

References

  1. Armer JM. The Problem of Post-Breast Cancer Lymphedema: Impact and Measurement Issues. Cancer Invest. 2005;23(1):76-83. https://doi.org/10.1081/CNV-48707
  2. Li L, et al. Current Treatments for Breast Cancer-Related Lymphoedema: A Systematic Review. Asian Pac J Cancer Prev. 2016;17(11):4875-83. https://doi.org/10.22034/APJCP.2016.17.11.4875
  3. Erickson VS, et al. Arm Edema in Breast Cancer Patients. J Natl Cancer Inst. 2001;93(2):96-111. https://doi.org/10.1093/jnci/93.2.96
  4. Disipio T, et al. Incidence of Unilateral Arm Lymphoedema after Breast Cancer: a Systematic Review and Meta-Analysis. Lancet Oncol. 2013;14(6):500-15. https://doi.org/10.1016/S1470-2045(13)70076-7
  5. Lee KW, et al. The Risk Factors Associated with Lymphedema after Axillary Dissection for Breast Cancer. J Korean Surg Soc. 2006;71(2):85-9.
  6. Meek AG. Breast Radiotherapy and Lymphedema. Cancer Suppl. 1998;83(12):2788-97. https://doi.org/10.1002/(SICI)1097-0142(19981215)83:12B+<2788::AID-CNCR27>3.0.CO;2-I
  7. Casley-Smith JR. Modern Treatment of Lymphoedema. Mod Med Aust. 2002;5:70-83.
  8. Yeom CH. The Update Treatment of Lymph-edema. Kwandong Medical Journal. 2004;8(2):59-67.
  9. Cassileth BR, et al. A safety and efficacy pilot study of acupuncture for the treatment of chronic lymphoedema. Acupunct Med. 2011;29(3):170-2. https://doi.org/10.1136/aim.2011.004069
  10. Lee JY, et al. Two Cases of Cancerinduced Lymphedema Patients Treated with Oryeong-san. Korean J Orient Int Med. 2013;34(3):322-8.
  11. Jang EH, et al. Acupotomy and venesection in Upper Limb Lymphedema and Peripheral neuropathy following Breast Cancer Surgery. J Pharmacopuncture. 2009;12(4):119-26. https://doi.org/10.3831/KPI.2009.12.4.119
  12. Kim EG, et al. A Case Report of lymphedema due to axillary lymph node dissection. Journal of the Korea Institute of Oriental Medical Informatics. 2008;14(2):95-103.
  13. Smith CA, Pirotta M, Kilbreath S. A feasibility study to examine the role of acupuncture to reduce symptoms of lymphoedema after breast cancer: a randomised controlled trial. Acupunct Med. 2014;32(5):387-93. https://doi.org/10.1136/acupmed-2014-010593
  14. Cassileth BR, et al. Acupuncture in the treatment of upper-limb lymphedema: results of a pilot study. Cancer. 2013;119(13):2455-61. https://doi.org/10.1002/cncr.28093
  15. Jeong YJ, et al. Treatment of Lymphedema with Saam Acupuncture in Patients with Breast Cancer: A Pilot Study. Med Acupunct. 2015;27(3):206-15. https://doi.org/10.1089/acu.2014.1071
  16. Yao C, et al. Effects of warm acupuncture on breast cancer-related chronic lymphedema: A randomized controlled trial. Curr Oncol. 2016;23(1):27-34. https://doi.org/10.3747/co.23.2788
  17. Chen J, et al. 28 Cases of Acupuncture Treatment on Postoperative Lymphedema in Breast Cancer. Zhejiang J Tradit Chin Med. 2016;51(12):905.
  18. Jin M, et al. Clinical effects of laser acupuncture treatment on breast cancer-related lymphoedema. China Medical Herald. 2017;14(20):101-4.
  19. Bao T, et al. Acupuncture for breast cancer-related lymphedema: a randomized controlled trial. Breast Cancer Res Treat. 2018;170(1):77-87. https://doi.org/10.1007/s10549-018-4743-9
  20. Wu CX. Effect of Abdominal Acupuncture and Upper Limb Exercise for Breast Cancer Related Lymphedema. Chin Med J Metall Indus. 2018;35(3):324-5.
  21. Bower JE, et al. Fatigue in breast cancer survivors: occurrence, correlates, and impact on quality of life. JCO. 2000;18(4):743-53. https://doi.org/10.1200/JCO.2000.18.4.743
  22. Lee JY, et al. A Review on Randomized Controlled Clinical Study on Acupuncture Treatment of Breast Cancer Patients. J Korean Obstet Gynecol. 2016;29(1):78-91. https://doi.org/10.15204/jkobgy.2016.29.1.078
  23. Korean Acupuncture and Moxibustion Society. The Acupuncture and Moxibustion Medicine. Seoul:Jipmoondang Publishing Co. 2012:5, 752-3.
  24. Professors of Korean Medical Physiology. Oriental Medical Physiology. Seoul: Jipmoondang Publishing Co. 2008:157-8.
  25. Kanakura Y, et al. Effectiveness of acupuncture and moxibustion treatment for lymphedema following intrapelvic lymph node dissection: a preliminary report. Am J Chin Med. 2002;30(1):37-43. https://doi.org/10.1142/S0192415X02000041
  26. Meridians & Acupoints Textbook Compilation Committee. Details of Meridians & Acupoints; A Guidebook for College Students. 7th ed. Daejeon: Jongryeonamu Publishing Co. 2016:162-3.
  27. Meridians & Acupoints Textbook Compilation Committee. Principles of Meridians & Acupoints; A Guidebook for College Students. 7th ed. Daejeon: Jongryeonamu Publishing Co. 2015:109-14, 196-201, 235-8.

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