The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Clinical Research Trends in Respiratory Diseases Related to Particulate Matter

미세먼지 관련 호흡기질환 임상연구 동향

  • Lyu, Yee Ran (Division of Respiratory System, Dept. of Internal Medicine, College of Korean Medicine, Dae-Jeon University) ;
  • Kim, JinHoo (Division of Respiratory System, Dept. of Internal Medicine, College of Korean Medicine, Dae-Jeon University) ;
  • Yang, Won-kyung (Division of Respiratory System, Dept. of Internal Medicine, College of Korean Medicine, Dae-Jeon University) ;
  • Kim, Seung-hyeong (Institute of Traditional Medicine and Bioscience, Dae-Jeon University) ;
  • Park, Yang-Chun (Division of Respiratory System, Dept. of Internal Medicine, College of Korean Medicine, Dae-Jeon University)
  • 유이란 (대전대학교 한의과대학 폐계내과학교실) ;
  • 김진후 (대전대학교 한의과대학 폐계내과학교실) ;
  • 양원경 (대전대학교 한의과대학 폐계내과학교실) ;
  • 김승형 (대전대학교 동서생명과학연구원) ;
  • 박양춘 (대전대학교 한의과대학 폐계내과학교실)
  • Received : 2019.06.07
  • Accepted : 2019.07.08
  • Published : 2019.06.30
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Abstract

Objectives: This study aimed to review the clinical research trends in respiratory diseases related to particulate matter (PM) to help design clinical studies on herbal medicine that protects against PM. Methods: We searched three international databases (Pubmed, EMBASE, and CENTRAL) to investigate clinical studies on respiratory diseases related to PM and to analyze their study design, respiratory-related disease, inclusion/exclusion criteria, study period, outcome measure, study results, measurement method of PM and range of PM. Results: A total of 18 studies were finally selected, including 13 observational studies and 5 randomized controlled trials. The selected studies showed an increasing trend from 1985 to 2018 and were conducted mostly in North America, followed by Europe and Asia. Subject disease and age were decided in variety by each study objective, although asthma accounted for the majority. For the outcome assessment, pulmonary function test was mostly used for lung function. Quality of life questionnaires and biomarkers in blood and sputum were also used. Conclusion: A well-designed clinical study on herbal medicine that protects against PM is needed, and this study is expected to be used as base data.

Keywords

References

  1. OECD. The economic consequences of outdoor air pollution. 2016.6.
  2. Pope CA 3rd1, Dockery DW. Health effects of fine particulate air pollution: lines that connect. Journal of the air & waste management association 2006;56(6):709-42. https://doi.org/10.1080/10473289.2006.10464485
  3. Lee MS. Government Policy Trends related to Particulate Matter. NEWS & INFORMATION FOR CHEMICAL ENGINEERS Vol. 35, No. 5, 2017.
  4. World Health Organization. Air pollution including WHO's 1999 guidelines for air pollution control. Geneva: World Health Organization; 2000.
  5. Begum BA, Biswas SK, Hopke PK. Source apportionment of air particulate matter by chemical mass balance (CMB) and comparison with positive matrix factorization (PMF) model. Aerosol and Air Quality Research 2007;7(4):446-68. https://doi.org/10.4209/aaqr.2006.10.0021
  6. Air Quality Research Division. Study on the Composition of PM2.5 in the Yellow Sand and Fine Particle. Incheon: National Institute of Environmental Research; 2008.
  7. Seagrave J. Mechanisms and implications of air pollution particle associations with chemokines. Toxicology and applied pharmacology 2008;232(3):469-77. https://doi.org/10.1016/j.taap.2008.08.001
  8. Myong JP. Health effects of particulate matter. The Korean Journal of Medicine 2016;91(2):106-13. https://doi.org/10.3904/kjm.2016.91.2.106
  9. Loomis D, Huang W, Chen G. The International Agency for Research on Cancer (IARC) evaluation of the carcinogenicity of outdoor air pollution: focus on China. Chinese journal of cancer 2014;33(4):189. https://doi.org/10.5732/cjc.014.10028
  10. Kyung SY, Kim YS, Kim WJ, Park MS, Song JW, Yum H, et al. Guideline for the prevention and managementof particulate matter/Asian dust particleinduced adverse health effect on the patients withpulmonary diseases. Journal of the Korean Medical Association 2015;58(11):1060-9. https://doi.org/10.5124/jkma.2015.58.11.1060
  11. Donaldson K, Stone V, Borm PJ, Jimenez LA, Gilmour PS, Schins RP, et al. Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10). Free Radical Biology and Medicine2003;34(11):1369-82. https://doi.org/10.1016/S0891-5849(03)00150-3
  12. Ministry of Health & Welfare. Health Impacts of Air Pollution in Korea. Seoul: Korea; 2016.
  13. Kleinman MT, Bailey RM, Whynot JD. Controlled exposure to a mixture of SO2, NO2, and particulate air pollutants: effects of human pulmonary function and respiratory symptoms. Archives of environmental health 1985;40(4):197-201. https://doi.org/10.1080/00039896.1985.10545917
  14. Wang B, Peng Z, Zhang X, Xu Y, Wang H, Allen G, et al. Particulate matter, sulfur dioxide, and pulmonary function in never-smoking adults in Chongqing, China. International journal of occupational and environmental health : official journal of the International Commission on Occupational Health1999;5(1):14-9. https://doi.org/10.1179/oeh.1999.5.1.14
  15. Gong H Jr, Linn WS, Sioutas C, Terrell SL, Clark KW, Anderson KR, et al. Controlled exposures of healthy and asthmatic volunteers to concentrated ambient fine particles in Los Angeles. Inhal Toxicol 2003;15(4):305-25. https://doi.org/10.1080/08958370304455
  16. Slaughter JC, Lumley T, Sheppard L, Koenig JQ, Shapiro GG. Effects of ambient air pollution on symptom severity and medication use in children with asthma. Ann Allergy Asthma Immunol 2003;91(4):346-53. https://doi.org/10.1016/S1081-1206(10)61681-X
  17. Schildcrout JS, Sheppard L, Lumley T, Slaughter JC, Koenig JQ, Shapiro GG. Ambient air pollution and asthma exacerbations in children: an eight-city analysis. Am J Epidemiol 2006;164(6):505-17. https://doi.org/10.1093/aje/kwj225
  18. Bedada GB, Heinrich J, Gotschi T, Downs SH, Forsberg B, Jarvis D, et al. Urban background particulate matter and allergic sensitization in adults of ECRHS II. International Journal of Hygiene and Environmental Health 2007;210(6):691-700. https://doi.org/10.1016/j.ijheh.2006.11.005
  19. Qian Z, Lin HM, Chinchilli VM, Lehman EB, Duan Y, Craig TJ, et al. Interaction of ambient air pollution with asthma medication on exhaled nitric oxide among asthmatics. Arch Environ Occup Health 2009;64(3):168-76. https://doi.org/10.1080/19338240903240616
  20. Anderson HR, Ruggles R, Pandey KD, Kapetanakis V, Brunekreef B, Lai CK, et al. Ambient particulate pollution and the world-wide prevalence of asthma, rhinoconjunctivitis and eczema in children: Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC). Occup Environ Med 2010;67(5):293-300. https://doi.org/10.1136/oem.2009.048785
  21. Roy A, Hu W, Wei F, Korn L, Chapman RS, Zhang J. Ambient particulate matter and lung function growth in Chinese children. Epidemiology 2012;23(3):464-72. https://doi.org/10.1097/EDE.0b013e31824cbd6d
  22. Karottki DG, Spilak M, Frederiksen M, Gunnarsen L, Brauner EV, Kolarik B, et al. An indoor air filtration study in homes of elderly: cardiovascular and respiratory effects of exposure to particulate matter. Environmental health: a global access science source 2013;12:116. https://doi.org/10.1186/1476-069X-12-116
  23. Alexis NE, Huang YC, Rappold AG, Kehrl H, Devlin R, Peden DB. Patients with asthma demonstrate airway inflammation after exposure to concentrated ambient particulate matter. Am J Respir Crit Care Med 2014;190(2):235-7. https://doi.org/10.1164/rccm.201401-0126LE
  24. Guarnieri M, Diaz E, Pope D, Eisen EA, Mann J, Smith KR. Lung function in rural guatemalan women before and after a chimney stove intervention to reduce wood smoke exposure results from the randomized exposure study of pollution indoors and respiratory eff ects and chronic respiratory effects of early childhood exposure to respirable particulate matter study. Chest 2015;148(5):1184-92. https://doi.org/10.1378/chest.15-0261
  25. Kariisa M, Foraker R, Pennell M, Buckley T, Diaz P, Criner GJ, et al. Short- and long-term effects of ambient ozone and fine particulate matter on the respiratory health of chronic obstructive pulmonary disease subjects. Archives of environmental & occupational health 2015;70(1):56-62. https://doi.org/10.1080/19338244.2014.932753
  26. Zhou Y, Chen X, Zou W, Zhao D, Li X, Pu J, et al. Association between exposure to ambient particulate matter and chronic obstructive pulmonary disease: results from a cross-sectional study in China. Thorax (no pagination), 2016 2016;Date of Publication: December 16.
  27. Meliton AY, Cho T, Hamanaka RB, Nigdelioglu R, Sun K, Budinger GS, et al. Short-term acute exposure of healthy humans to particulate matter induces differential gene expression in lung immune cells. American journal of respiratory and critical care medicine 2017;195:1.
  28. Watanabe M, Noma H, Kurai J, Sano H, Hantan D, Ueki M, et al. A panel study of airborne particulate matter composition versus concentration: Potential for inflammatory response and impaired pulmonary function in children. Allergol Int 2017;66(1):52-8. https://doi.org/10.1016/j.alit.2016.04.014
  29. Holm SM, Balmes J, Gillette D, Hartin K, Seto E, Lindeman D, et al. Cooking behaviors are related to household particulate matter exposure in children with asthma in the urban East Bay Area of Northern California. PLoS One 2018;13(6):e0197199. https://doi.org/10.1371/journal.pone.0197199
  30. Pirozzi CS, Mendoza DL, Xu Y, Zhang Y, Scholand MB, Baughman RP. Short-Term Particulate Air Pollution Exposure is Associated with Increased Severity of Respiratory and Quality of Life Symptoms in Patients with Fibrotic Sarcoidosis. International journal of environmental research and public health 2018;15(6):1077. https://doi.org/10.3390/ijerph15061077
  31. Krishnan RM, Adar SD, Szpiro AA, Jorgensen NW, Van Hee VC, Barr RG, et al. Vascular responses to long- and short-term exposure to fine particulate matter: MESA Air (Multi-Ethnic Study of Atherosclerosis and Air Pollution). J Am Coll Cardiol 2012;60(21):2158-66. https://doi.org/10.1016/j.jacc.2012.08.973
  32. Ristovski ZD, Miljevic B, Surawski NC, Morawska L, Fong KM, Goh F, et al. Respiratory health effects of diesel particulate matter. Respirology 2012;17(2):201-12. https://doi.org/10.1111/j.1440-1843.2011.02109.x
  33. Jang AS. Impact of particulate matter on health. Journal of the Korean Medical Association 2014;57(9):763-8. https://doi.org/10.5124/jkma.2014.57.9.763
  34. Pope CA 3rd. Mortality effects of longer term exposures to fine particulate air pollution: review of recent epidemiological evidence. Inhalation toxicology 2007;19(sup1):33-8. https://doi.org/10.1080/08958370701492961
  35. Air Quality Research Division. Study on the Composition of PM2.5 in the Yellow Sand and Fine Particle. Incheon: National Institute of Environmental Research; 2008.
  36. Choi YJ, Park JK, Jung WS. Synoptic Meteorological Classification of the Days on Which Asthma Deaths Occurred Due to High PM 10 Concentrations in Seoul. Journal of Environmental Science International 2017;26(2):159-72. https://doi.org/10.5322/JESI.2017.26.2.159
  37. Seo JH, Ha EH, Lee BE, Park HS, Kim H, Hong YC, et al. The Effect of PM 10 on Respiratory-related Admission in Seoul. Journal of Korean Society for Atmospheric Environment 2006;22(5):564-73.
  38. Kim OJ, Kim SJ, Kim H, Long-term exposure to fine particulate air pollution and mortality in a South Korean population-based cohort. The Korean Society of Environmental Toxicology 2017:2017(10):265
  39. Allen RW, Barn PK, Lanphear BP. Randomized controlled trials in environmental health research: unethical or underutilized? PLoS medicine 2015;12(1):e1001775. https://doi.org/10.1371/journal.pmed.1001775
  40. Mann C. Observational research methods. Research design II: cohort, cross sectional, and case-control studies. Emergency medicine journal 2003;20(1):54-60. https://doi.org/10.1136/emj.20.1.54
  41. Bruce N, Perez-Padilla R, Albalak R. The health effects of indoor air pollution exposure in developing countries. World Health Organization 2002.
  42. Gong H, Jr., Sioutas C, Linn WS. Controlled exposures of healthy and asthmatic volunteers to concentrated ambient particles in metropolitan Los Angeles. Res Rep Health Eff Inst 2003;(118):1-36; discussion 7-47.
  43. Ryu DG. DongUi-Physiology-GangUi. Iksan: Wonkwang University Publisher; 1996, p. 215.
  44. National Oriental Medicine College of Pumlonolgy. Pulmonology. 2nd. Seoul: Nado; 2013, p. 8.
  45. National Oriental Medicine College of Traditional herbal medicine. Traditional herbal medicine. 2nd. Seoul: Jungeumsa; 2011, p. 497, 499, 513, 645, 683.
  46. Lee W, Bae JS. Inhibitory effects of Kyung-Ok-Ko, traditional herbal prescription, on particulate matter-induced vascular barrier disruptive responses. International journal of environmental health research 2019;29(3):301-11. https://doi.org/10.1080/09603123.2018.1542490
  47. Yang WK, Protective effect of GHX02 on particulate matter-induced lung injury. Daejeon University 2019.

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