Ceramist (세라미스트)

The Korean Ceramic Society (한국세라믹학회)
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Recent Progress in MRI Contrast Agent with Ceramic LDH Nanohybrids

세라믹 LDH 나노하이브리드를 이용한 MRI 조영제의 최신 연구동향

  • Ha, Seongjin (Department of Nano Materials Science and Engineering, Kyungnam University) ;
  • Jin, Wenji (Department of Nano Materials Science and Engineering, Kyungnam University) ;
  • Park, Dae-Hwan (Department of Nano Materials Science and Engineering, Kyungnam University)
  • 하성진 (경남대학교 나노신소재공학과) ;
  • 김문희 (경남대학교 나노신소재공학과) ;
  • 박대환 (경남대학교 나노신소재공학과)
  • Received : 2019.08.29
  • Accepted : 2019.09.10
  • Published : 2019.09.30
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Abstract

Ceramic layered double hydroxide (LDH) nanohybrids have attracted considerable interest in biomedical science due to their unique structural feature and characteristics in biological condition. Many studies on LDH nanoparticles have been reported in diagnosis applications including magnetic resonance imaging (MRI) contrast agents in order to not only provide better imaging performance through multimodal imaging strategy, but realize therapeutic function which treat cancers in one platform. This review highlights the recent progress in MRI T1 contrast agent, dual modal imaging system, and MRI-guided drug delivery systems ranging from synthetic method and characterization to evaluation in vitro and in vivo based on the ceramic LDH nanohybrids. Future research directions are also suggested for next-generation bio-imaging contrast agent.

Keywords

References

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