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Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature

  • Depa, Jayaramakrishna (Department of Nephrology, Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai) ;
  • Coritsidis, George (Department of Nephrology, Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai)
  • Received : 2018.10.17
  • Accepted : 2019.02.07
  • Published : 2019.06.30

Abstract

Minimal change disease (MCD) in children has a favorable long-term prognosis, and development of end-stage renal disease is very uncommon; less than 5%. In the first case of its kind, we report a 21-year-old female with a history of MCD at the age of 6, who had late relapse subsequent to a motorcycle accident resulting in a de-gloving skin injury and intensive care unit admission. MCD was confirmed by normal light microscopy, podocyte effacement on electron microscopy and absence of any deposits on immunofluorescence 3 weeks after the incident due to critical illness. It is postulated that the skin injury is what caused the relapse of MCD.

Keywords

References

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