Fig. 1. Reducing power of extractions from C. wilsonii Nakai.
Fig. 2. Inhibitory effect of extract from C. wilsonii Nakai on cytotoxicity of RAW264.7 cell.
Fig. 3. The effect of C. wilsonii Nakai on LPS-induced NO production in RAW264.7 cell.
Fig. 4. HPLC chromatograms of standard compounds and methanolic extracts from C. wilsonii Nakai.
Table 1. DPPH radical scavenging activity of extractions from C. wilsonii Nakai.
Table 2. The total phenolic and flavonoid contents of extractions from C. wilsonii Nakai.
Table 3. Calibration curve of standard and limit of detection (LOD) and, limit of quantitation (LOQ).
Table 4. The difference in the content of phenolic acid composition of the C. wilsonii Nakai.
참고문헌
- Bauer G. (2000). Reactive oxygen and nitrogen species: Efficient, selective, and interactive signals during intercellular induction of apoptosis. Anticancer Research. 20:4115-4139.
- Blois MS. (1958). Antioxidant determinations by the use of a stable free radical. Nature. 181:1199-1200. https://doi.org/10.1038/1811199a0
- Chang CS and Jeon JI. (2003). Leaf flavonoids in Cotoneaster wilsonii(Rosaceae) from the island Ulleung-do, Korea. Biochemical Systematics and Ecology. 31:171-179. https://doi.org/10.1016/S0305-1978(02)00064-9
- Chung HY, Cesari M, Anton S, Marzetti E, Giovannini S, Seo AY, Christy C, Carter C, Yu BP and Leeuwenburgh C. (2009). Molecular inflammation: Underpinnings of aging and age-related diseases. Ageing Research Reviews. 8:18-30. https://doi.org/10.1016/j.arr.2008.07.002
- Duan Y, Kim GH, Seong JH, Chung HS and Kim HS. (2015). Antioxidant activities of n-butanol and ethyl acetate extracts from Yam(Dioscorea batatas Decne). Journal of the Korean Oil Chemists' Society. 32:599-606. https://doi.org/10.12925/jkocs.2015.32.4.599
- Elizabeth A. Miles, Zoubouli P, Calder P and Phil D. (2005). Differential anti-inflammatory effects of phenolic compounds from extra virgin olive oil identified in human whole blood cultures. Nutrition. 21:389-394. https://doi.org/10.1016/j.nut.2004.06.031
- Green DR and Kroemer G. (2005). Pharmacological manipulation of cell death: Clinical applications in sight? Journal of clinical investigation. 115:2610-2617. https://doi.org/10.1172/JCI26321 (cited by 2019 April 8).
- Hwang SJ, Kim YW, Park YH, Lee HJ and Kim KW. (2014). Anti-inflammatory effects of chlorogenic acid in lipopolysaccharidestimulated RAW264.7 cells. Inflammation Research. 63:81-90. https://doi.org/10.1007/s00011-013-0674-4
- Kim CS, Kim J, Lee YM, Sohn E, Jo K and Kim JS. (2011). Inhibitory effects of chlorogenic acid on aldose reductase activity in vitro and cataractogenesis in galactose-fed rats. Archives of Pharmacal Research. 34:847-852. https://doi.org/10.1007/s12272-011-0519-z
- Kim HS, Kim MS, Kim SH, Yun KW and Song JH. (2013). Analysis of total phenolic content and antioxidant activity from fruits of Vaccinium oldhamii Miq. Journal of Korean Society of Forest Science. 102:566-570. https://doi.org/10.14578/jkfs.2013.102.4.566
- Kim YH, Cho ML, KIm D, Shin GH, Lee JH, Lee JS, Park SO, Lee SJ, Shin HM and Lee OH. (2015). The antioxidant activity and their major antioxidant compounds from Acanthopanax senticosus and A. koreanum. Molecules. 20:13281-13295. https://doi.org/10.3390/molecules200713281
- Kim YS, Chang CS, Shin HT, Kim H and Choi DY. (2002). Conservational status of Cotoneaster wilsonii on island Ulleung-do. Korean Journal of Plant Taxonomy. 32:159-175. https://doi.org/10.11110/kjpt.2002.32.2.159
- Lim JS, Park SY, Lim JO and Lee BW. (2013). A faunastic study of insects from is. Ulleungdo and its nearby islands in South Korea. Journal of Asia-Pacific Biodiversity. 6:93-121. https://doi.org/10.7229/jkn.2013.6.1.093
- Liu XP, Jia J, Jing XM and Li GI. (2018). Antioxidant activities of extracts from sarcocarp of Cotoneaster multiflorus. Journal of Chemistry. 2018:4619768. https://https://doi.org/10.1155/2018/4619768 (cited by 2019 May 20).
- Mosmann T. (1983). Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. Journal of Immunological Methods. 65:55-63. https://doi.org/10.1016/0022-1759(83)90303-4
- Nieva Moreno MI, Isla MI, Sampietro AR and Vattuone MA. (2000). Comparison of the free radical-scavenging activity of propolis from several regions of Argentine. Journal of Ethnopharmacology. 71:109-114. https://doi.org/10.1016/S0378-8741(99)00189-0
- Nordberg J and Arner ESJ. (2001). Reactive oxygen species, antioxidants, and the mammallan thioredoxin system. Free Radical Biology and Medicine. 31:1287-1312. https://doi.org/10.1016/S0891-5849(01)00724-9
- Omaye ST, Reddy KA and Cross CE. (1997). Effect of butylated hydroxytoluene and other antioxidants on mouse lung metabolism. Journal of Toxicology and Environmental Health. 3:829-836.
- Oyaizu M. (1986). Studies on products of browning reactions: Antioxidative activities of products of browning reaction prepared from glucosamine. Japanese Journal of Nutrition. 44:307-315. https://doi.org/10.5264/eiyogakuzashi.44.307
- Rice-Evans CA, Miller NJ and Paganga G. (1996). Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Biology and Medicine. 20:933-956. https://doi.org/10.1016/0891-5849(95)02227-9
- Singleton VL and Rossi JA. (1965). Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. American Journal of Enology and Viticulture. 16:144-158.
- Uysal A, Zengin G, Mollica A, Gunes E, Locatelli M, Yilmaz T and Aktumsek A. (2016). Chemical and biological insights on Cotoneaster integerrimus: A new(-)-epicatechin source for food and medicinal applications. Phytomedicine. 23:979-988. https://doi.org/10.1016/j.phymed.2016.06.011
- Yi MR, Kang CH and Bu HJ. (2017). Antioxidant and anti-inflammatory activity of extracts from kohlrabi(Brassica Oleracea var. Gonglodes). Journal of the Korean Oil Chemists' Society. 34:189-202.
- Zou Y, Liao S, Shen W, Liu F, Tang C, Chen CYO and Sun Y. (2012). Phenolics and antioxidant activity of mulberry leaves depend on cultivar and harvest month in southern China. International Journal of Molecular Sciences. 13:16544-16553. https://doi.org/10.3390/ijms131216544 (cited by 2019 May 15).