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Effects of Aromatherapy on Agitation in Patients with Dementia: A Systematic Literature Review and Meta-analysis

아로마 요법이 치매 환자의 초조행동에 미치는 효과: 체계적 문헌고찰 및 메타분석

  • Kim, Eun Kyung (College of Nursing, Research Institute of Nursing Science, Keimyung University) ;
  • Park, Heeok (College of Nursing, Research Institute of Nursing Science, Keimyung University) ;
  • Lee, Chun Hee (Department of Nursing, Sunlin University) ;
  • Park, Eunsil (Department of Nursing, Yeungjin University)
  • 김은경 (계명대학교 간호과학연구소) ;
  • 박희옥 (계명대학교 간호대학.간호과학연구소) ;
  • 이춘희 (선린대학교 간호학과) ;
  • 박은실 (영진전문대학교 간호학과)
  • Received : 2018.12.14
  • Accepted : 2019.05.01
  • Published : 2019.06.30

Abstract

Purpose: The purpose of this study is to identify the effects of aromatherapy on agitation in patients with dementia using a meta-analysis and systemic literature review. Methods: The EMBASE, CINAHL, MEDLINE, and other databases were searched up to November 2017. Results: Of 419 publications identified, 12 met inclusion criteria, and 9 studies were used to estimate the effect size of aromatherapy. A total of 837 participants across all studies were included. The commonly applied methods were massage (50%), type of oil lavender (75%), and instrument Cohen-Mansfield Agitation Inventory (75%). A medium effect size of aromatherapy on agitation was identified (d=-0.56, $I^2=65.0%$, p=.001). The massage group has lower effect size than the other group (d=-0.98, $I^2=0.0%$, p=.001). Conclusion: Aromatherapy appears to be effective in improving agitation in patients with dementia. However, further studies for home-dwelling patients with dementia and with different types of aroma oil should be conducted in the future. In addition, research with well-designed are needed to assess the effects or aromatherapy on agitation.

Keywords

References

  1. Livingston G, Kelly L, Lewis-Holmes E, Baio G, Morris S, Patel N, et al. Non-pharmacological interventions for agitation in dementia: Systematic review of randomized controlled trials. The British Journal of Psychiatry. 2014;205(6):436-442. https://doi.org/10.1192/bjp.bp.113.141119
  2. Kong E, Evans LK, Guevara JP. Non-pharmacological intervention for agitation in dementia: A systematic review and meta-analysis. Aging & Mental Health. 2009;13(4):512-520. https://doi.org/10.1080/13607860902774394
  3. Yang MH, Lin LC, Wu SC, Chiu JH, Wang PN, Lin JG. Comparison of the efficacy of aroma-acupressure and aromatherapy for the treatment of dementia-associated agitation. BioMed Central Complementary and Alternative Medicine. 2015;15(1):93. https://doi.org/10.1186/s12906-015-0612-9
  4. Cohen-Mansfield J, Billig N. Agitated behaviors in the elderly: I. conceptual review. Journal of the American Geriatrics Society. 1986;34(10):711-721. https://doi.org/10.1111/j.1532-5415.1986.tb04302.x
  5. Cerejeira J, Lagarto L, Mukaetova-Ladinska EB. Behavioral and psychological symptoms of dementia. Frontiers in Neurology. 2012;3(73):1-21. https://doi.org/10.3389/fneur.2012.00073
  6. Suh GH. Agitated behaviours among the institutionalized elderly with dementia: Validation of the Korean version of the Cohen-Mansfield Agitation Inventory. International Journal of Geriatric Psychiatry. 2004;19(4):378-385. https://doi.org/10.1002/gps.1097
  7. Shin Y, Chung S. Anxiety and agitation in BPSD. Journal of Korean Geriatric Psychiatry. 2000;4(1):24-33.
  8. Lee SB, Kim KW. Nonpharmacological interventions for Alzheimer's disease. Journal of the Korean Medical Association. 2009;52(11):1069-1076. https://doi.org/10.5124/jkma.2009.52.11.1069
  9. Kim CM, Park MS, Kim SH. Analysis of trends in non-pharmacological studies for elders with dementia in Korea. Journal of Korean Gerontological Nursing. 2012;14(2):129-141.
  10. Holmes C, Ballard C. Aromatherapy in dementia. Advanced in Psychiatric Treatment. 2004;10(4):296-300. https://doi.org/10.1192/apt.10.4.296
  11. Ballard CG, O'Brien JT, Reichelt K, Perry EK. Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: The results of a double-blind, placebo-controlled trial with Melissa. The Journal of Clinical Psychiatry. 2002;63(7):553-558. https://doi.org/10.4088/JCP.v63n0703
  12. Yoshiyama K, Arita H, Suzuki J. The effect of aroma hand massage therapy for people with dementia. Journal of Alternative and Complementary Medicine (New York, NY). 2015;21(12):759-765. https://doi.org/10.1089/acm.2015.0158
  13. Burns A, Perry E, Holmes C, Francis P, Morris J, Howes MJ, et al. A double-blind placebo-controlled randomized trial of Melissa officinalis oil and donepezil for the treatment of agitation in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 2011;31(2):158-164. https://doi.org/10.1159/000324438
  14. Forrester LT, Maayan N, Orrell M, Spector AE, Buchan LD, Soares Weiser K. Aromatherapy for dementia (Review). Cochrane Database of Systematic Reviews. 2014;2:1-60.
  15. Pedersen SKA, Andersen PN, Lugo RG, Andreassen M, Sutterlin S. Effects of music on agitation in dementia: A meta-analysis. Frontiers in psychology. 2017;8:742. https://doi.org/10.3389/fpsyg.2017.00742
  16. Higgins J, Green S. Cochrane handbook for systematic reviews of interventions: Version 5.1.0 [Internet]. London, UK: The Cochrane Collaboration; 2011 [cited 2018 September 7]. Available from: http://handbook.cochrane.org/.
  17. Kim SY, Park JE, Seo HJ, Lee YJ, Jang BH, Son HJ, et al. NECA's guidance for undertaking systematic reviews and meta-analyses for intervention. Seoul: National Evidence-Based Healthcare Collaborating Agency; 2011. Report No.: 978-89-94581-59-0.
  18. Borenstein M, Hedges LV, Higgins JPT, Rothstein HR. In: Introduction to meta-analysis. West Sussex: John Wiley and Sons; 2009. 421 p.
  19. Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Mahwah. NJ: Lawrence Erlbaum Associates; 1998. 567 p.
  20. Yang MH, Lin LC, Wu SC, Chiu JH, Wang PN, Lin JG. Comparison of the efficacy of aroma-acupressure and aromatherapy for the treatment of dementia-associated agitation. BMC Complementary & Alternative Medicine. 2015;15(1):1-8. https://doi.org/10.1186/s12906-015-0612-9
  21. Yang YP, Lee FP, Chao HC, Hsu FY, Wang JJ. Comparing the effects of cognitive simulation, reminiscence, and aroma-massage on agitation and depressive mood in people with dementia. Journal of the American Medical Directors Association. 2016;17(8):719-724. https://doi.org/10.1016/j.jamda.2016.03.021
  22. Cohen-Mansfield J. Agitated behavior in persons with dementia: The relationship between type of behavior, its frequency, and its disruptiveness. Journal of Psychiatric Research. 2008;43(1):64-69. https://doi.org/10.1016/j.jpsychires.2008.02.003
  23. Kim SJ, Ryoo EN, Park KS. A study on pain, physical function, cognitive function, depression and agitation in elderly women with dementia. Journal of Korean Academy of Adult Nursing. 2007;19(3):401-412.
  24. Oh BH, Kim YK, Kim JH, Shin YS. The effects of cognitive rehabilitation training on cognitive function of elderly dementia patients. Journal of Korean Neuropsychiatric Association. 2003;42(4):514-519.
  25. Shim YS, Kim BS, Shon YM, Kim KS, Yoon B, Yang DW. Clinical characteristics of demented patients in a geriatric institution: Focused on behavioral and psychological symptoms. Dementia and Neurocognitive Disorders. 2005;4(1):35-40.
  26. Hwang E, Shin S. The effects of aromatherapy on sleep improvement: A systematic literature review and meta-analysis. The Journal of Alternative and Complementary Medicine. 2015;21(2):61-68. https://doi.org/10.1089/acm.2014.0113
  27. Roh KH, Park H. A meta-analysis of the effects of aromatherapy on psychological variables in nursing. Journal of Korean Academy of Community Health Nursing. 2009;20(2):113-122.
  28. Buckle J. Massage and aromatherapy massage: Nursing art and science. International Journal of Palliative Nursing. 2003;8(6):276-280. https://doi.org/10.12968/ijpn.2002.8.6.10497
  29. Choi SW. Effect of aromatherapy on behavioral and psychological symptoms of dementia. Korean Journal of Gerontology Society. 2008;28(4):1069-1087.
  30. Lee SY. Effects of aromatherapy and foot reflex massage on emotion, sleep disturbance, and wandering behavior in older adults with dementia. The Korean Journal of Rehabilitation Nursing. 2013;16(1):9-17. https://doi.org/10.7587/kjrehn.2013.9