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Fungal Genomics in Dermatology

  • Lee, Young Bok (Department of Dermatology, College of Medicine, The Catholic University of Korea) ;
  • Lee, Soo Young (Department of Dermatology, College of Medicine, The Catholic University of Korea) ;
  • Seo, Ji Min (Department of Dermatology, College of Medicine, The Catholic University of Korea) ;
  • Kang, Min Ji (Department of Dermatology, College of Medicine, The Catholic University of Korea) ;
  • Yu, Dong Soo (Department of Dermatology, College of Medicine, The Catholic University of Korea)
  • Received : 2019.06.06
  • Accepted : 2019.06.24
  • Published : 2019.06.30

Abstract

To date, hundreds of fungal genomes have been sequenced, and many more are underway. Recently developed cutting-edge techniques generate very large amounts of data, and the field of fungal genomics in dermatology has consequently evolved substantially. Methodological improvements have broadened the scope of large-scale ecological studies in dermatology, including biodiversity assessments and genomic identification of fungi. Here, we aimed to provide a brief introduction to bioinformatic approaches to fungal genomics in the field of dermatology. We described the history and basic concepts of fungal genomics and presented sequencing-based techniques for fungal identification, including a list of the revised taxa of dermatophytes, as determined by current phylogenetic analysis. Finally, we discussed the emerging trends in fungal genomics in dermatology, such as next-generation sequencing.

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Acknowledgement

This study was supported by a grant from the National Research Foundation of Korea (No. 2019R1F1A1056601), funded by the Korean Ministry of Science, ICT, and Future Planning (MSIP). The authors wish to acknowledge the financial support of The Catholic University of Korea Uijeongbu St. Mary's Hospital Clinical Research Laboratory Foundation made in the program year of 2018.