Neonatal Medicine

  • 제26권4호
  • /
  • Pages.198-203
  • /
  • 2019
  • /
  • 2287-9412(pISSN)
  • /
  • 2287-9803(eISSN)
대한신생아학회 (The Korean Society of Neonatology)
권호 표지
DOI QR코드

DOI QR Code

Perinatal Risk Factors for Postnatal Weight Loss in Late Preterm Infants

  • Bae, Seong Phil (Department of Pediatrics, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine) ;
  • Song, Jun Hwan (Department of Pediatrics, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine) ;
  • Hahn, Won-Ho (Department of Pediatrics, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine) ;
  • Koh, Ji Won (Department of Pediatrics, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine) ;
  • Kim, Ho (Department of Pediatrics, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine)
  • 투고 : 2019.05.22
  • 심사 : 2019.07.08
  • 발행 : 2019.11.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Purpose: Many studies have reported associations of early postnatal growth failure in preterm infants with several morbidities. However, the risk factors for postnatal weight loss (PWL) in late preterm infants have not been identified. We investigated the independent risk factors for PWL in late preterm infants. Methods: This was a retrospective cohort study. We enrolled 369 late preterm infants born at 34+0 to 36+6 weeks gestational age who were admitted to the Soonchunhyang University Cheonan Hospital between 2015 and 2017. PWL% was calculated as (birth weight-lowest weight)/birth weight×100. The infants were classified into lower (<5%) and higher (≥10%) PWL% groups by propensity score matching for gestational age, sex, and birth weight. Perinatal risk factors were analyzed using multivariable logistic regression. Results: The lower and higher PWL% groups included 62 and 31 infants, respectively. Antenatal steroids administered within 1 week before birth (odds ratio [OR], 3.26; 95% confidence interval [CI], 1.015 to 10.465; P=0.047), lower total calorie intake during days 1 to 7 (OR, 0.98; 95% CI, 0.977 to 0.999; P=0.027), and phototherapy (OR, 5.28; 95% CI, 1.327 to 21.024; P=0.018) were independent risk factors for the higher PWL%. Conclusion: Further studies are needed to identify the risk factors that cause high PWL% according to gestational age and short- and long-term morbidities based on the degree of PWL.

키워드

참고문헌

  1. Paul IM, Schaefer EW, Miller JR, Kuzniewicz MW, Li SX, Walsh EM, et al. Weight change nomograms for the first month after birth. Pediatrics 2016;138:e20162625. https://doi.org/10.1542/peds.2016-2625
  2. Jaiswal A, Murki S, Gaddam P, Reddy A. Early neonatal morbidities in late preterm infants. Indian Pediatr 2011;48:607-11. https://doi.org/10.1007/s13312-011-0105-y
  3. Teune MJ, Bakhuizen S, Gyamfi Bannerman C, Opmeer BC, van Kaam AH, van Wassenaer AG, et al. A systematic review of severe morbidity in infants born late preterm. Am J Obstet Gynecol 2011;205:374.
  4. Tsai ML, Lien R, Chiang MC, Hsu JF, Fu RH, Chu SM, et al. Prevalence and morbidity of late preterm infants: current status in a medical center of Northern Taiwan. Pediatr Neonatol 2012;53:171-7. https://doi.org/10.1016/j.pedneo.2012.04.003
  5. Muelbert M, Harding JE, Bloomfield FH. Nutritional policies for late preterm and early term infants: can we do better? Semin Fetal Neonatal Med 2019;24:43-7. https://doi.org/10.1016/j.siny.2018.10.005
  6. Aksoy HT, Guzoglu N, Eras Z, Gokce IK, Canpolat FE, Uras N, et al. The association of early postnatal weight loss with outcome in extremely low birth weight infants. Pediatr Neonatol 2019;60:192-6. https://doi.org/10.1016/j.pedneo.2018.06.003
  7. Bauer K, Versmold H. Postnatal weight loss in preterm neonates less than 1,500 g is due to isotonic dehydration of the extracellular volume. Acta Paediatr Scand Suppl 1989;360:37-42. https://doi.org/10.1111/j.1651-2227.1989.tb11280.x
  8. Hartnoll G, Betremieux P, Modi N. Body water content of extremely preterm infants at birth. Arch Dis Child Fetal Neonatal Ed 2000;83:F56-9. https://doi.org/10.1136/fn.83.1.F56
  9. Eriksson L, Haglund B, Ewald U, Odlind V, Kieler H. Short and long-term effects of antenatal corticosteroids assessed in a cohort of 7,827 children born preterm. Acta Obstet Gynecol Scand 2009;88:933-8. https://doi.org/10.1080/00016340903111542
  10. Mulder EJ, de Heus R, Visser GH. Antenatal corticosteroid therapy: short-term effects on fetal behaviour and haemodynamics. Semin Fetal Neonatal Med 2009;14:151-6. https://doi.org/10.1016/j.siny.2008.10.003
  11. Wapner RJ, Sorokin Y, Mele L, Johnson F, Dudley DJ, Spong CY, et al. Long-term outcomes after repeat doses of antenatal corticosteroids. N Engl J Med 2007;357:1190-8. https://doi.org/10.1056/NEJMoa071453
  12. Verma RP, Shibli S, Fang H, Komaroff E. Clinical determinants and utility of early postnatal maximum weight loss in fluid management of extremely low birth weight infants. Early Hum Dev 2009;85:59-64. https://doi.org/10.1016/j.earlhumdev.2008.06.011
  13. Omar SA, DeCristofaro JD, Agarwal BI, La Gamma EF. Effects of prenatal steroids on water and sodium homeostasis in extremely low birth weight neonates. Pediatrics 1999;104(3 Pt 1):482-8. https://doi.org/10.1542/peds.104.3.482
  14. Sifianou P, Thanou V, Karga H. Metabolic and hormonal effects of antenatal betamethasone after 35 weeks of gestation. J Pediatr Pharmacol Ther 2015;20:138-43. https://doi.org/10.5863/1551-6776-20.2.138
  15. Gyamfi-Bannerman C, Thom EA, Blackwell SC, Tita AT, Reddy UM, Saade GR, et al. Antenatal betamethasone for women at risk for late preterm delivery. N Engl J Med 2016;374:1311-20. https://doi.org/10.1056/NEJMoa1516783
  16. Thorp JA, Jones PG, Peabody JL, Knox E, Clark RH. Effect of antenatal and postnatal corticosteroid therapy on weight gain and head circumference growth in the nursery. Obstet Gynecol 2002;99:109-15. https://doi.org/10.1016/S0029-7844(01)01657-X
  17. Battin M, Bevan C, Harding J. Growth in the neonatal period after repeat courses of antenatal corticosteroids: data from the ACTORDS randomised trial. Arch Dis Child Fetal Neonatal Ed 2012;97:F99-105. https://doi.org/10.1136/adc.2011.211318
  18. Moltu SJ, Blakstad EW, Strommen K, Almaas AN, Nakstad B, Ronnestad A, et al. Enhanced feeding and diminished postnatal growth failure in very-low-birth-weight infants. J Pediatr Gastroenterol Nutr 2014;58:344-51. https://doi.org/10.1097/mpg.0000000000000220
  19. Lee SM, Kim N, Namgung R, Park M, Park K, Jeon J. Prediction of postnatal growth failure among very low birth weight infants. Sci Rep 2018;8:3729. https://doi.org/10.1038/s41598-018-21647-9
  20. Binchy A, Moore Z, Patton D. Feeding intervals in premature infants ≤1750 g: an integrative review. Adv Neonatal Care 2018;18:168-78. https://doi.org/10.1097/ANC.0000000000000486
  21. Li YW, Yan CY, Yang L, Han ZL. Effect of breastfeeding versus formula milk feeding on preterm infants in the neonatal intensive care unit. Zhongguo Dang Dai Er Ke Za Zhi 2017;19:572-5.
  22. Verma RP, Shibli S, Komaroff E. Postnatal transitional weight loss and adverse outcomes in extremely premature neonates. Pediatr Rep 2017;9:6962.
  23. Modi N. Clinical implications of postnatal alterations in body water distribution. Semin Neonatol 2003;8:301-6. https://doi.org/10.1016/S1084-2756(03)00043-5
  24. Salas AA, Salazar J, Burgoa CV, De-Villegas CA, Quevedo V, Soliz A. Significant weight loss in breastfed term infants readmitted for hyperbilirubinemia. BMC Pediatr 2009;9:82. https://doi.org/10.1186/1471-2431-9-82
  25. Wadhawan R, Oh W, Perritt R, Laptook AR, Poole K, Wright LL, et al. Association between early postnatal weight loss and death or BPD in small and appropriate for gestational age extremely low-birth-weight infants. J Perinatol 2007;27:359-64. https://doi.org/10.1038/sj.jp.7211751
  26. Oh W, Poindexter BB, Perritt R, Lemons JA, Bauer CR, Ehrenkranz RA, et al. Association between fluid intake and weight loss during the first ten days of life and risk of bronchopulmonary dysplasia in extremely low birth weight infants. J Pediatr 2005;147:786-90. https://doi.org/10.1016/j.jpeds.2005.06.039
  27. Bertini G, Perugi S, Elia S, Pratesi S, Dani C, Rubaltelli FF. Transepidermal water loss and cerebral hemodynamics in preterm infants: conventional versus LED phototherapy. Eur J Pediatr 2008;167:37-42. https://doi.org/10.1007/s00431-007-0421-3