Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Epilepsy Surgery in Children versus Adults

  • Lee, Ki Hyeong (Comprehensive Epilepsy Center, Advent Health for Children) ;
  • Lee, Yun-Jin (Comprehensive Epilepsy Center, Advent Health for Children) ;
  • Seo, Joo Hee (Comprehensive Epilepsy Center, Advent Health for Children) ;
  • Baumgartner, James E. (Comprehensive Epilepsy Center, Advent Health for Children) ;
  • Westerveld, Michael (Comprehensive Epilepsy Center, Advent Health for Children)
  • Received : 2019.01.22
  • Accepted : 2019.02.24
  • Published : 2019.05.01
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Abstract

Epilepsy is one of the most common chronic neurological disorder affecting 6-7 per 1000 worldwide. Nearly one-third of patients with newly diagnosed epilepsy continue to have recurrent seizures despite adequate trial of more than two anti-seizure drugs : drug-resistant epilepsy (DRE). Children with DRE often experience cognitive and psychosocial co-morbidities requiring more urgent and aggressive treatment than adults. Epilepsy surgery can result in seizure-freedom in approximately two-third of children with improvement in cognitive development and quality of life. Understanding fundamental differences in etiology, co-morbidity, and neural plasticity between children and adults is critical for appropriate selection of surgical candidates, appropriate presurgical evaluation and surgical approach, and improved overall outcome.

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References

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