미생물학회지 (Korean Journal of Microbiology)

  • 제55권1호
  • /
  • Pages.74-76
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  • 2019
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  • 0440-2413(pISSN)
  • /
  • 2383-9902(eISSN)
한국미생물학회 (The Microbiological Society of Korea)
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한국 노인 여성의 치태에서 분리된 Actinomyces georgiae KHUD_A1의 유전체 염기서열 해독

Genome sequence of Actinomyces georgiae KHUD_A1 isolated from dental plaque of Korean elderly woman

  • 문지회 (경희대학교 치과대학 악안면생체공학교실) ;
  • 신승윤 (경희대학교 치과대학 치주과학교실) ;
  • 홍원영 (경희대학교 치과대학 악안면생체공학교실) ;
  • 장은영 (경희대학교 대학원 치의학과) ;
  • 양석빈 (경희대학교 치과대학 악안면생체공학교실) ;
  • 류재인 (경희대학교 치과대학 예방치과학교실) ;
  • 이진용 (경희대학교 치과대학 악안면생체공학교실) ;
  • 이재형 (경희대학교 치과대학 악안면생체공학교실)
  • Moon, Ji-Hoi (Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University) ;
  • Shin, Seung-Yun (Department of Periodontology, School of Dentistry, Kyung Hee University) ;
  • Hong, Won Young (Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University) ;
  • Jang, Eun-Young (Department of Dentistry, Graduate School, Kyung Hee University) ;
  • Yang, Seok Bin (Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University) ;
  • Ryu, Jae-In (Department of Preventive Dentistry, School of Dentistry, Kyung Hee University) ;
  • Lee, Jin-Yong (Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University) ;
  • Lee, Jae-Hyung (Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University)
  • 투고 : 2019.01.02
  • 심사 : 2019.01.16
  • 발행 : 2019.03.31
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초록

그람 양성 혐기성 간균 Actinomyces는 구강 인두, 위장관 및 비뇨 생식 기관의 점막 표면에서 흔히 서식한다. 본 논문에서는 한국 노인 여성의 치태에서 분리된 Actinomyces georgiae KHUD_A1의 유전체 염기서열을 분석하여 보고한다. 이 균주의 유전체는 2,652,059 bp의 크기로 GC 함량은 68.06%이며, CPBP family intramembrane metalloprotease 유전자와 bile acid: sodium symporter family protein 유전자 등 157개의 KHUD_A1 균주 특이적인 유전자들을 포함한다. 이 유전체의 서열 정보는 A. georgiae종의 일반적인 특성과 Actinomyces속의 유전체 다양성을 이해하는데 유용한 정보를 제공할 것이다.

Gram-positive anaerobic bacilli Actinomyces spp. commonly reside on mucosal surfaces of the oropharynx, gastrointestinal tract, and urogenital tract. Here, we first report the draft genome sequence of Actinomyces georgiae KHUD_A1, isolated from dental plaque of a Korean elderly woman. The genome is 2,652,059 bp in length and has a GC content of 68.06%. The genome includes 2,242 protein-coding genes, 9 rRNAs, and 64 tRNA. We identified 157 KHUD_A1 strain-specific genes, including genes encoding CPBP family intramembrane metalloprotease, bile acid: sodium symporter family protein, Txe/YoeB family addiction module toxin and Phd/YefM family antitoxin. The sequence information of A. georgiae KHUD_A1 will help understand the general characteristics of the bacterial species and the genome diversity of the genus Actinomyces.

키워드

MSMHBQ_2019_v55n1_74_f0001.png 이미지

Fig. 1. The pan-genome of Actinomyces georgiae.

Table 1. Genome features of Actinomyces georgiae KHUD_A1

MSMHBQ_2019_v55n1_74_t0001.png 이미지

참고문헌

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