3도 화상에 대한 동종 상피세포 치료제의 효과 보고

Feasibility of Cultured Allogenic Keratinocyte Treatment for Third Degree Burns

  • 최장연 (가톨릭대학교 의과대학 의정부성모병원 성형외과) ;
  • 조진태 (가톨릭대학교 의과대학 의정부성모병원 성형외과) ;
  • 최종윤 (가톨릭대학교 의과대학 의정부성모병원 성형외과) ;
  • 서보미 (가톨릭대학교 의과대학 의정부성모병원 성형외과) ;
  • 정성노 (가톨릭대학교 의과대학 의정부성모병원 성형외과)
  • Choi, Jangyoun (Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Cho, Jin Tae (Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Choi, Jong Yun (Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Seo, Bommie Florence (Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Jung, Sung-No (Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea)
  • 투고 : 2019.10.17
  • 심사 : 2019.11.15
  • 발행 : 2019.12.31

초록

Allogenic keratinocyte application is widely used for treatment of second degree burns. However, there is no significant body of report on application of allogenic keratinocyte to third degree burns. A geriatric patient visited our burn center showing second to third-degree burn on dorsum of her left hand. Considering the surface area and wound depth, surgery was indicated but her medical condition and age made the surgery high risk for a long operation. Therefore, chemical escharolysis, serial bedside debridement, and cultured allogenic keratinocyte (Kaloderm®, Tegoscience, Seoul, Korea) application was done. The wound was completely epithelialized after four rounds of Kaloderm® application. For third-degree burns where definitive surgical reconstruction is precluded due to medical comorbidity of the patient, we investigated the possibility of allogenic keratinocyte treatment which may allow to avoid high-risk anesthesia and surgery.

키워드