Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Correlation between physicochemical properties and biological half-life of triazole fungicides in perilla leaf

들깻잎에서 Triazole계 살균제의 생물학적 반감기와 물리화학적 특성과의 상관관계

  • Lee, Sang-Hyeob (School of Applied Biosciences, Kyungpook National University) ;
  • Kwak, Se-Yeon (School of Applied Biosciences, Kyungpook National University) ;
  • Hwang, Jeong-In (School of Applied Biosciences, Kyungpook National University) ;
  • Kim, Hyo-Jung (School of Applied Biosciences, Kyungpook National University) ;
  • Kim, Tae-Hwa (Analysis Technology and Tomorrow) ;
  • Kim, Jang-Eok (School of Applied Biosciences, Kyungpook National University)
  • Received : 2019.10.15
  • Accepted : 2019.11.06
  • Published : 2019.12.31
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Abstract

The biological half-life of pesticides applied on crops is the key indicator for ensuring the safety of agricultural products. The biological half-life is affected by the several factors like growing conditions of the crop, climate, application method, and physicochemical properties of pesticides. In this study, the biological half-life was calculated and the degradation rates of six triazole fungicides sprayed on perilla leaves were evaluated. Moreover, the statistical analysis confirmed the correlation between the biological half-life and physicochemical properties of six triazole pesticides. The recoveries of the six pesticides were between 84.8-104.9%, which satisfied the residual pesticide analysis criteria. The biological half-life of six pesticides sprayed on perilla leaves, calculated using the first-order kinetics model, ranged between 6.4-15.1 days. When the biological half-life and the physicochemical properties were correlated using the principal component analysis: pKa and Log P, the biological half-life was found to be affected by PC1. The correlation coefficient between biological half-life and physicochemical properties (pKa), calculated by Spearman rank-order correlation, was R2 = -0.928 (p <0.01). Biological half-life has been shown to correlate with pKa. In conclusion, it can be used as a database for the relationship between biological half-life and physicochemical properties and will contribute to ensure safe supply of agricultural products.

들깻잎에 살포된 triazole계 살균제 6종에 대하여 생물학적 반감기를 산출하고 분해 및 소실 속도를 확인하였으며, 통계분석으로 생물학적 반감기와 농약의 물리화학적 특성간의 상관관계를 확인하였다. 확립된 분석법으로 6종 농약의 회수율 시험 결과 84.8-104.9%로 잔류농약분석법 기준을 만족하였다. 들깻잎에 살포한 농약 6종의 생물학적 반감기는 first-order kinetics model으로 산출하였으며, 그 결과 6.4-15.1일로 나타났다. 산출된 생물학적 반감기와 6종의 농약의 물리화학적 특성을 주성분 분석으로 상관성을 확인하였을 때, pKa, Log P 및 생물학적 반감기가 PC1에 영향을 받아 상관성이 있는 것으로 나타났다. Spearman rank-order correlation으로 생물학적 반감기와 물리화학적 특성간의 상관계수를 산출하였을 때, 생물학적 반감기와 pKa는 R2 = -0.928, p <0.01로 나타나, 생물학적 반감기는 pKa와 상관성이 있는 것으로 나타났다.

Keywords

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