Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics (대한후두음성언어의학회지)

The Korean Society of Laryngology, Phoniatrics and Logopedics. (대한후두음성언어의학회)
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The Effect of Steroid Therapy for Idiopathic Unilateral Vocal Cord Palsy

특발성 일측성 성대마비에서 경구 스테로이드 요법의 효과

  • Bae, Jong-Won (Department of Otorhinolaryngology-Head and Neck Surgery, Chilgok Kyungpook National University Hospital, Kyungpook National University School of Medicine) ;
  • Lee, GilJoon (Department of Otorhinolaryngology-Head and Neck Surgery, Chilgok Kyungpook National University Hospital, Kyungpook National University School of Medicine)
  • 배종원 (경북대학교 의과대학 칠곡경북대학교병원 이비인후-두경부외과학교실) ;
  • 이길준 (경북대학교 의과대학 칠곡경북대학교병원 이비인후-두경부외과학교실)
  • Received : 2019.10.15
  • Accepted : 2019.11.29
  • Published : 2019.12.30
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Abstract

Background and Objectives Idiopathic unilateral vocal fold paralysis (IVFP) is believed to be due to inflammation and edema of the recurrent laryngeal nerve caused by viral diseases such as upper respiratory tract infections. Corticosteroid has a potent anti-inflammatory action which should minimize nerve damage. The purpose of this study was to investigate the effect of oral steroid therapy on IVFP. Materials and Method Study was performed for the IVFP patient from January 2012 to August 2017. Patient's dermography, direction and location of paralyzed vocal cords, history of hypertension, diabetes, cerebrovascular disease, and other underlying disease, smoking history, alcohol consumption and upper respiratory tract infection, and symptoms were investigated. Treatment was divided into three groups: the observation group, low-dose group, and high-dose group, and the recovery rate and time of vocal cord paralysis were analyzed in each group. Results Thirty-seven patients were enrolled in this study. There was no relationship between oral steroid use, dosage and recovery of vocal cord paralysis. Oral steroids showed a rapid recovery of vocal cord paralysis, but there was no statistically significant difference in the time of recovery of vocal palsy with or without steroids (p=0.673). In addition, there was no statistically significant difference in recovery rate between the period to start of treatment, presence of diabetes mellitus, and treatment modality, but the recovery rate was high in the group with upper respiratory tract infection history (p=0.041). Conclusion In IVFP, oral steroid therapy has no significant difference in time and extent of recovery compared to the case of spontaneous recovery.

Keywords

References

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