Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Two New Caffeoyl Threonate Esters from the Leaves of Toxicodendron vernicifluum

  • Jang, Jae Young (College of Pharmacy, Chungbuk National University) ;
  • Ahn, Jong Hoon (College of Pharmacy, Chungbuk National University) ;
  • Jo, Yang Hee (College of Pharmacy, Chungbuk National University) ;
  • Turk, Ayman (College of Pharmacy, Chungbuk National University) ;
  • Kang, So Young (Department of Aqualife Medicine, Chonnam National University) ;
  • Hwang, Bang Yeon (College of Pharmacy, Chungbuk National University) ;
  • Lee, Mi Kyeong (College of Pharmacy, Chungbuk National University)
  • Received : 2019.10.27
  • Accepted : 2019.12.02
  • Published : 2019.12.31
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Abstract

Toxicodendron vernicifluum, also called as Rhus verniciflua is a deciduous tree belonging to Anacardiaceae family. Two new caffeoyl threonate esters, rhuseols A (1) and B (2), together with 5-O-(E)-caffeoylquinic acid methyl ester (3) were isolated from the leaves of T. vernicifluum. The structures of isolated compounds were established by using 1D and 2D NMR in combination with HR-ESI-MS. Compounds 1 - 3 showed DPPH radical scavenging effects with IC50 values of 47.9, 107.8 and 15.4 μM, respectively. Taken together, these compounds might contribute to the antioxidant properties of the leaves of T. vernicifluum, which will be useful for various oxidative stress mediated diseases.

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References

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