Therapeutic Science for Rehabilitation (재활치료과학)

Korean Society of Neurological Occupational Therapy (대한신경계작업치료학회)
권호 표지
DOI QR코드

DOI QR Code

Development of Computerized Screening Test Items for Mild Cognitive Impairment

경도인지장애 선별을 위한 전산화 평가 항목 개발

  • Park, Jin-Hyuck (Dept. of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology) ;
  • Park, Ji-Hyuk (Dept. of Occupational Therapy, College of Health and Science, Yonsei University)
  • 박진혁 (한국과학기술원 바이오및뇌공학과) ;
  • 박지혁 (연세대학교 보건과학대학 작업치료학과)
  • Received : 2018.09.06
  • Accepted : 2018.11.03
  • Published : 2018.11.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objective: This study was to develop computerized screening test items for mild cognitive impairment. Methods: Through literature reviews, items from computerized tests for screening mild cognitive impairment were extracted. A panel of professional experts validated that the items were important and fit to screen for mild cognitive impairment. Results: A total 37 items were extracted from 12 computerized tests and 11 new items were added through the first panel review. After that, 18 items were removed via the second panel review. Finally, 16 items were selected by analyzing content validity ratio. 16 items consisted of memory, attention, and executive function areas. Conclusions: A total of 16 computerized test items were developed. It is urgent to validate them to screen mild cognitive impairment. Moreover, standardization studies for this test are required in the future.

목적 : 본 연구는 경도인지장애 선별을 위한 전산화 평가 항목을 개발하는 것이다. 연구방법 : 문헌고찰을 통해 경도인지장애 선별을 위해 사용되는 기존의 전산화 평가에서 항목들을 추출하였다. 이후 델파이 기법을 실시하였으며, 전문가 패널들의 의견을 취합하여 추출된 항목들을 수정 및 보완하고 최종적으로 중요도 및 적합도를 판단하여 평가 항목들을 선택하였다. 결과 : 문헌고찰을 통해 12개의 전산화 평가에서 37개의 항목을 추출을 하였고 1차적으로 전문가들의 의견을 통해 11개의 항목을 추가하였다. 이후 2차 전문가 모임을 통해 48개의 항목에서 경도인지장애 선별에 부적합한 18개의 항목이 제거되었다. 마지막으로 내용타당도 분석을 실시한 결과, 30개 항목에서 12개 항목이 제거되어 최종적으로 16개의 항목이 선택되었다. 최종 16개의 항목은 주의력, 기억력, 실행기능 영역으로 구성되었다. 결론 : 경도인지장애 선별을 위한 16개의 전산화 평가 항목이 개발되었다. 추후 이 항목들을 이용하여 타당성 연구를 실시하여 경도인지장애 선별에 적합한지 확인할 필요가 있다. 또한 이 전산화 평가를 정상 노인 및 경도인지장애 노인에게 실시하여 전산화 평가에 대한 표준화 연구를 진행하여 임상에서 사용할 수 있도록 해야 할 것이다.

Keywords

References

  1. Ahmed, S., Arnold, R., Thompson, S. A., Graham, K. S., & Hodges, J. R. (2008). Naming of objects, faces and buildings in mild cognitive impairment. Cortex, 44, 746-752. doi: 10.1016/j.cortex.2007.02.002.
  2. Albert, M. S., Moss, M. B., Tanz, R., & Jones, K. (2001). Preclinical prediction of AD using neuropsychological tests. Journal of the International Neuropsychological Society, 7, 631-639. doi: 10.1017/S1355617701755105.
  3. Cho, B-H., Lee, J-S., Kim, S-K., & Cha, T-H. (2016). Development of screening test items for geriatric mild cognitive impairment. The Journal of Korean Society of Occupational Therapy, 23, 57-71. doi: 10.14519/jksot.2016.23.2.05.
  4. Choi, H., & Suh, C-J. (2011). Study on R&D manpower requirements for the field of pharmaceutical - An application of delphi method. Journal of Korea Academia-Industrial Cooperation Society, 12, 1270-1277. https://doi.org/10.5762/KAIS.2011.12.3.1270
  5. Cummings, J. L., Vinters, H. V., Cole, G. M., & Khachaturian, Z. S. (1998). Alzheimer's disease: Etiologies, pathophysiology, cognitive reserve, and treatment opportunities. Neurology, 51, S2-S17. doi:10.1212/WNL.51.1_Suppl_1.S2.
  6. De Jager, C. A., Schrijnemaekers, A. C., Honey, T. E., & Budge, M. M. (2009). Detection of MCI in the clinic: Evaluation of the sensitivity and specificity of a computerised test battery, the hopkins verbal learning test and the MMSE. Age and Ageing, 38, 455-460. doi:10.1093/ageing/afp068.
  7. De Lepeleire, J., Heyrman, J., Baro, F., & Buntinx, F. (2005). A combination of tests for the diagnosis of dementia had a significant diagnostic value. Journal of Clinical Epidemiology, 58, 217-225. doi: 10.1016/j,jclinepi.2004.07.005.
  8. Lawshe, C. H. (1975). A quantitative approach to content validity. Personnel Psychology, 29, 563-575.
  9. Lindsay, J., Laurin, D., Verreault, R., Hebert, R., Helliwell, B., Hill, G. B., ... & McDowell, I. (2002). Risk factors for Alzheimer's disease: A prospective analysis from the Canadian study of health and aging. American Journal of Epidemiology, 156, 445-453. doi: 10.1093/aje/kwf074.
  10. Memoria, C. M., Yassuda, M. S., Nakano, E. Y., & Forlenza, O. V. (2014). Contributions of the computer-administered neuropsychological screen for mild cognitive impairment (CANS-MCI) for the diagnosis of MCI in Brazil. International Psychogeriatrics, 26, 1483-1491. doi:10.1017/S104161024000726.
  11. Park, J. H., & Park, J. H. (2016). A systematic review on computerized cognitive function test for screening mild cognitive impairment. The Journal of Korean Society of Occupational Therapy, 24, 19-31. doi: 10.14519/jksot.2016.24.2.02.
  12. Petersen, R. C. (2004). Mild cognitive impairment as a diagnostic entity. Journal of Internal Medicine, 256, 183-194. doi: 10.1111/j.1365-2796.2004.01388.x.
  13. Phillips, M., Rogers, P., Haworth, J., Bayer, A., & Tales, A. (2013). Intra-individual reaction time variability in mild cognitive impairment and Alzheimer's disease: Gender, processing load and speed factors. PloS One, 8, e65712. doi: 10.1371/journal.pone.0065712.
  14. Roberts, J. L., Clare, L., & Woods, R. T. (2009). Subjective memory complaints and awareness of memory functioning in mild cognitive impairment: A systematic review. Dementia and Geriatric Cognitive Disorders, 28, 95-109. doi: 10.1159/000234911.
  15. Roselli, F., Tartaqlione, B., Federico, F., Lepore, V., Defazio, G., & Livrea, P. (2009). Rate of MMSE score change in Alzheimer's disease: Influence of education and vascular risk factors. Clinical Neurology and Neurosurgery, 114, 27-330. doi: 10.1016/j.clineuro.2008. 10.006.
  16. Silveri, M. C., Reali, G., Jenner, C., & Piopolo, M. (2007). Attention and memory in the preclinical stage of dementia. Journal of Geriatric Psychiatry and Neurology, 20, 67-75. doi: 10.1177/0891988706297469.
  17. Wouters, H., van Campen, J., Appels, B., Lindeboom, R., Buiter, M., de Hann, R. J., & Schmand, B. (2014). Does adaptive cognitive testing combine efficiency with precision? Prospective findings. Journal of Alzheimer's Disease, 25, 595-603. doi: 10.3233/JAD-2011-101743.
  18. Zygouris, S., & Tsolaki, M. (2015). Computerized cognitive testing for older adults: A review. American Journal of Alzheimer's Disease & Other Dementia, 30, 13-28. doi: 10.1177/1533317514522852