참고문헌
- Gazewood JD, Richards DR and Clebak K (2013) Parkinson disease: an update. Am Fam Physician 87, 267-273
- Smeyne M and Smeyne RJ (2013) Glutathione metabolism and Parkinson's disease. Free Radic Biol Med 62, 13-25 https://doi.org/10.1016/j.freeradbiomed.2013.05.001
- Malkus KA, Tsika E and Ischiropoulos H (2009) Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle. Mol Neurodegener 4, 24 https://doi.org/10.1186/1750-1326-4-24
- Bloem BR, Irwin I, Buruma OJ et al (1990) The MPTP model: versatile contributions to the treatment of idiopathic Parkinson's disease. J Neurol Sci 97, 273-293 https://doi.org/10.1016/0022-510X(90)90225-C
- Cleeter MW, Cooper JM and Schapira AH (1992) Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement. J Neurochem 58, 786-789 https://doi.org/10.1111/j.1471-4159.1992.tb09789.x
-
Yi F, He X and Wang D (2013) Lycopene protects against
$MPP^{+}$ -induced cytotoxicity by maintaining mitochondrial function in SH-SY5Y cells, Neurochem Res 38, 1747-1757 https://doi.org/10.1007/s11064-013-1079-z - Ojha S, Javed H, Azimullah S et al (2016) Betacaryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson disease. Mol Cell Biochem 418, 59-70 https://doi.org/10.1007/s11010-016-2733-y
- Lowe JT, Lee MD, Akella LB et al (2012) Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries. J Org Chem 77, 7187-7211 https://doi.org/10.1021/jo300974j
- Han Y, Han M, Shin D et al (2012) Exploration of novel 3-substituted azetidine derivatives as triple reuptake inhibitors. J Med Chem 55, 8188-8192 https://doi.org/10.1021/jm3008294
- Dalla Y, Singh N, Jaggi AS et al (2009) Potential of ezetimibe in memory deficits associated with dementia of Alzheimer's type in mice. Indian J Pharmacol 41, 262-267 https://doi.org/10.4103/0253-7613.59925
- Kim J, Kim SM, Na JM et al (2016) Protective effect of 3-(naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride on hypoxia-induced toxicity by suppressing microglial activation in BV2 cells. BMB Rep 49, 687-692 https://doi.org/10.5483/BMBRep.2016.49.12.169
- Kim EA, Na JM, Kim J et al (2017) Neuroprotective effect of 3-(naphthalen-2-yl(propoxy)methyl) azetidine hydrochloride on brain ischaemia/reperfusion injury. J Neuroimmune Pharmacol 12, 447-461 https://doi.org/10.1007/s11481-017-9733-x
- Kim EA, Choi J, Han AR et al (2013) Anti-oxidative and anti-inflammatory effects of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride on glutamate-induced neurotoxicity in rat brain. Neurotoxicol 38, 106-114 https://doi.org/10.1016/j.neuro.2013.07.001
-
Cho CH, Kim J, Ahn JY et al (2015) N-adamantyl-4-methylthiazol-2-amine suppresses lipopolysaccharideinduced brain inflammation by regulating
$NF-{\kappa}B$ signaling in mice. J Neuroimmunol 289, 98-104 https://doi.org/10.1016/j.jneuroim.2015.10.016 - Rosa AI, Fonseca I, Nunes MJ et al (2017) Novel insights into the antioxidant role of tauroursodeoxycholic acid in experimental models of Parkinson's disease. Biochim Biophys Acta-Mol Basis Dis 1863, 2171-2181 https://doi.org/10.1016/j.bbadis.2017.06.004
- Hu XL, Song Q, Li X et al (2017) Neuroprotective effects of Kukoamine A on neurotoxin-induced Parkinson's model through apoptosis inhibition and autophagy enhancement. Neuropharmacology 117, 352e363 https://doi.org/10.1016/j.neuropharm.2017.02.022
- Choi WS, Yoon SY, Chang II et al (2000) Correlation between structure of Bcl-2 and its inhibitory function of JNK and caspase activity in dopaminergic neuronal apoptosis. J Neurochem 74, 1621-1626
- Borner C (2003) The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol Immunol 39, 615-647 https://doi.org/10.1016/S0161-5890(02)00252-3
- Ghosh A, Chandran K, Kalivendi SV et al (2010) Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model. Free Radic Biol Med 49, 1674-1684 https://doi.org/10.1016/j.freeradbiomed.2010.08.028
- Ramalingam M and Kim SJ (2014) The role of insulin against hydrogen peroxide-induced oxidative damages in differentiated SH-SY5Y cells. J Recept Signal Transduct 34, 212-220 https://doi.org/10.3109/10799893.2013.876043
-
Song JX, Shaw PC, Wong NS et al (2012) Chrysotoxine, a novel bibenzyl compound selectively antagonizes
$MPP^{+}$ , but not rotenone, neurotoxicity in dopaminergic SH-SY5Y cells. Neurosci Lett 521, 76-81 https://doi.org/10.1016/j.neulet.2012.05.063 - Chung HK, Kim OY, Lee H et al (2011) Relationship between dietary folate intake and plasma monocyte chemoattractant protein-1 and interleukin-8 in heart failure patients. J Clin Biochem Nutr 49, 62-66 https://doi.org/10.3164/jcbn.10-129
-
Ho PW, Chu AC, Kwok KH et al (2006) Knockdown of uncoupling protein-5 in neuronal SHSY5Y cells: effects on
$MPP^{+}$ -induced mitochondrial membrane depolarization, ATP deficiency, and oxidative cytotoxicity. J Neurosci Res 84, 1358-1366 https://doi.org/10.1002/jnr.21034 - Liu B, Gao HM, Wang JY et al (2002) Role of nitric oxide in inflammation-mediated neurodegeneration. Ann NY Acad Sci 962, 318-331 https://doi.org/10.1111/j.1749-6632.2002.tb04077.x
-
Obata T (2006) Nitric oxide and
$MPP^{+}$ -induced hydroxyl radical generation. J Neural Transm 113, 1131-1144 https://doi.org/10.1007/s00702-005-0415-0 -
Yurekli VA, Gurler S, Naziroglu M et al (2013) Zonisamide attenuates
$MPP^{+}$ -induced oxidative toxicity through modulation of$Ca^{2+}$ signaling and caspase-3 activity in neuronal PC12 cells. Cell Mol Neurobiol 33, 205-212 https://doi.org/10.1007/s10571-012-9886-3 - Lin LF, Doherty DH, Lile JD et al (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260, 1130-1132 https://doi.org/10.1126/science.8493557
- d'Anglemont de Tassigny X, Pascual A and Lopez-Barneo J (2015) GDNF based therapies, GDNF-producing interneurons, and trophic support of the dopaminergic nigrostriatal pathway. Implications for Parkinson's disease. Front Neuroanat 9, 10
- Lindholm D, Makela J, Di Liberto V et al (2016) Current disease modifying approaches to treat Parkinson's disease. Cell Mol Life Sci 73, 1365-1379 https://doi.org/10.1007/s00018-015-2101-1
-
Cheng YF, Zhu G, Wu QW et al (2017) GPR30 activation contributes to the puerarin-mediated neuroprotection in
$MPP^{+}$ -induced SH-SY5Y cell death. J Mol Neurosci 61, 227-234 https://doi.org/10.1007/s12031-016-0856-y