Acknowledgement
Supported by : Duksung Women's University
References
- Block L, Gosain A, King TW. Emerging therapies for scar prevention. Adv Wound Care (New Rochelle). 2015;4:607-14. https://doi.org/10.1089/wound.2015.0646
- Brown BC, Mckenna SP, Siddhi K, McGrouthe DA, Bayat A. The hidden cost of skin scars: quality of life after skin scarring. J Plast Reconstr Aesthet Surg. 2008;61:1049-58. https://doi.org/10.1016/j.bjps.2008.03.020
- Young VL, Hutchison J. Insights into patient and clinician concerns about scar appearance: semi quantitative structured surveys. Plast Reconstr Surg. 2009;124:256-65. https://doi.org/10.1097/PRS.0b013e3181a80747
- Cross KJ, Mustoe TA. Growth factors in wound healing. Surg Clin North Am. 2003;83:531-45. https://doi.org/10.1016/S0039-6109(02)00202-5
- Reish RG, Eriksson E. Scars: a review of emerging and currently available therapies. Plast Reconstr Surg. 2008;122:1068-78. https://doi.org/10.1097/PRS.0b013e318185d38f
- Campaner AB, Ferreira LM, Gragnani A, Bruder JM, Cusick JL, Morgan JR. Upregulation of TGF-beta1 expression may be necessary but is not sufficient for excessive scarring. J Invest Dermatol. 2006;126:1168-76. https://doi.org/10.1038/sj.jid.5700200
- Blom IE, Goldschmeding R, Leask A. Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy. Matrix Biol. 2002;21:473-82. https://doi.org/10.1016/S0945-053X(02)00055-0
- Chujo S, Shirasaki F, Kawara S, Inagaki Y, Kinbara T, Inaoki M, et al. Connective tissue growth factor causes persistent proalpha2(I) collagen gene expression induced by transforming growth factor-beta in a mouse fibrosis model. J Cell Physiol. 2005;203:447-56. https://doi.org/10.1002/jcp.20251
- Frazier K, Williams S, Kothapalli D, Klapper H, Grotendors GR. Stimulation of fibroblast cell growth, matrix production and granulation tissue formation by CTGF. J Invest Dermatol. 1996;107:404-11. https://doi.org/10.1111/1523-1747.ep12363389
- Sonnylal S, Shi-Wen X, Leoni P, Naff K, Van Pelt CS, Nakamura H, et al. Selective expression of CTGF in fibroblasts in vivo promotes systemic tissue fibrosis. Arthritis Rheum 2010;62:1523-32. https://doi.org/10.1002/art.27382
- Leask A, Holmes A, Abraham DJ. Connective tissue growth factor: a new and important player in the pathogenesis of fibrosis. Curr Rheumatol Rep. 2002;4:136-42. https://doi.org/10.1007/s11926-002-0009-x
- Li G, Xie Q, Shi Y, Li D, Zhang M, Jiang S, et al. Inhibition of CTGF by siRNA prevents liver fibrosis in rats. J Gene Med. 2006;8:889-900. https://doi.org/10.1002/jgm.894
- Nishio N, Ito S, Suzuki H, Isobe K. Antibodies to wounded tissue enhance cutaneous wound healing. Immunology. 2009;128:369-80. https://doi.org/10.1111/j.1365-2567.2009.03119.x
- Sisco M, Kryger ZB, O'Shaughnessy KD, Kim PS, Schultz GS, Ding XZ, et al. Antisense inhibition of connective tissue growth factor (CTGF/CCN2) mRNA limits hypertrophic scarring without affecting wound healing in vivo. Wound Repair Regen. 2008;16:661-73. https://doi.org/10.1111/j.1524-475X.2008.00416.x
- Daniels JT, Schultz GS, Blalock TD, Garrett Q, Grotendorst GR, Dean NM, et al. Mediation of transforming growth factor-beta(1)-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring. Am J Pathol. 2003;163:2043-52. https://doi.org/10.1016/S0002-9440(10)63562-6
- Whitehead KA, Langer R, Anderson DG. Knocking down barriers: advances in siRNA delivery. Nat Rev Drug Discov. 2009;8:129-38. https://doi.org/10.1038/nrd2742
- Eguchi A, Dowdy SF. siRNA delivery using peptide transduction domains. Trends Pharmacol Sci. 2009;30:341-5. https://doi.org/10.1016/j.tips.2009.04.009
- Wang JF, Olson ME, Ma L, Brigstock DR, Hart DA. Connective tissue growth factor siRNA modulates mRNA levels for a subset of molecules in normal and TGF-beta 1-stimulated porcine skin fibroblasts. Wound Repair Regen. 2004;12:205-16. https://doi.org/10.1111/j.1067-1927.2004.012113.x
- Berthod F, Germain L, Li H, Xu W, Damour O, Auger FA. Collagen fibril network and elastic system remodeling in a reconstructed skin transplanted on nude mice. Matrix Biol. 2001;20:463-73. https://doi.org/10.1016/S0945-053X(01)00162-7
- White JF, Werkmeister JA, Darby IA, Bisucci T, Birk DE, Ramshaw JA. Collagen fibril formation in a wound healing model. J Struct Biol. 2002;137:23-30. https://doi.org/10.1006/jsbi.2002.4460
- Moon H, Yong H, Lee AR. Optimum scratch assay condition to evaluate connective tissue growth factor for anti-scar therapy. Arch Pharm Res. 2012;35:383-8. https://doi.org/10.1007/s12272-012-0220-x
- Kim SC, Cho Lee A. Preparation of reproducible and responsive scar model and histology analysis. J Pharm Investig. 2010;40:45-9.
- Reid RR, Mogford JE, Butt R, deGiorgio-Miller A, Mustoe TA. Inhibition of procollagen C-proteinase reduces scar hyperthrophy in a rabbit model of cutaneous scarring. Wound Repair Regen. 2006;14:138-41. https://doi.org/10.1111/j.1743-6109.2006.00103.x
- Wyman TB, Nicol F, Zelphati O, Scaria PV, Plank C, Szoka FC Jr. Design, synthesis and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry. 1997;36:3008-17. https://doi.org/10.1021/bi9618474
- Crombez L, Aldrian-Herrada G, Konate K, Nguyen QN, McMaster GK, Brasseur R, Heitz F, et al. A new potent secondary amphipathic cell-penetrating peptide for siRNA delivery into mammalian cells. Mol Ther. 2009;17:95-103. https://doi.org/10.1038/mt.2008.215
- Mok H, Park TG. Self-crosslinked and reducible fusogenic peptides for intracellular delivery of siRNA. Biopolymers. 2007;89:881-8.
- Lee SH, Kim SH, Park TG. Intracellular siRNA delivery system using polyelectrolyte complex micelles prepared from VEGF siRNA-PEG conjugate and cationic fusogenic peptide. Biochem Biophys Res Commun. 2007;357:511-6. https://doi.org/10.1016/j.bbrc.2007.03.185
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