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Nutritional Support for Neurocritically Ill Patients

신경계 중환자의 영양 집중 치료

  • Jeong, Hae-Bong (Department of Critical Care Center, Seoul National University Hospital) ;
  • Park, Soo-Hyun (Department of Critical Care Center, Seoul National University Hospital) ;
  • Ryu, Ho Geol (Department of Critical Care Center, Seoul National University Hospital)
  • 정해봉 (서울대학교병원 중환자진료부) ;
  • 박수현 (서울대학교병원 중환자진료부) ;
  • 류호걸 (서울대학교병원 중환자진료부)
  • Received : 2018.11.16
  • Accepted : 2018.12.06
  • Published : 2018.12.30

Abstract

Nutritional assessment and support are often overlooked in the critically ill due to other urgent priorities. Unlike oxygenation, organ dysfunction, infection, or consciousness, there is no consensus of indicators. Making it difficult to evaluate the effectiveness of an intervention. Nevertheless, appropriate nutritional support in the critically ill has been associated with less morbidity and lower mortality. But, nutritional support has been considered an adjunct, for body weight maintenance and to help patients during the inflammatory phase of illness. Thus, it has been assigned a lower priority, compared to mechanical ventilation or hemodynamic stability. Recent findings have shown that nutritional support may prevent cellular injury due to oxidative stress and help strengthen the immune response. Large-scale randomized trials and clinical guidelines have shown a shift from nutritional support to nutritional therapy, with an emphasis on the importance of protein, minerals, vitamins, and trace elements. Nutrition is also important in neurocritically ill patients. Since there are few studies or recommendations with regard to the neurocritical population, the general recommendations for nutritional support should be applied.

Keywords

References

  1. Taylor BE, McClave SA, Martindale RG, Warren MM, Johnson DR, Braunschweig C, et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). Crit Care Med 2016;44:390-438.
  2. Davis CJ, Sowa D, Keim KS, Kinnare K, Peterson S. The use of prealbumin and C-reactive protein for monitoring nutrition support in adult patients receiving enteral nutrition in an urban medical center. JPEN J Parenter Enteral Nutr 2012;36:197-204. https://doi.org/10.1177/0148607111413896
  3. Heyland DK, Dhaliwal R, Jiang X, Day AG. Identifying critically ill patients who benefit the most from nutrition therapy: the development and initial validation of a novel risk assessment tool. Crit Care 2011;15:R268. https://doi.org/10.1186/cc10546
  4. Hubner M, Cerantola Y, Grass F, Bertrand PC, Schafer M, Demartines N. Preoperative immunonutrition in patients at nutritional risk: results of a double-blinded randomized clinical trial. Eur J Clin Nutr 2012;66:850-5. https://doi.org/10.1038/ejcn.2012.53
  5. Korfali G, Gundogdu H, Aydintug S, Bahar M, Besler T, Moral AR, et al. Nutritional risk of hospitalized patients in Turkey. Clin Nutr 2009;28:533-7. https://doi.org/10.1016/j.clnu.2009.04.015
  6. Kondrup J, Rasmussen HH, Hamberg O, Stanga Z, Ad Hoc ESPEN Working Group. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials. Clin Nutr 2003;22:321-36. https://doi.org/10.1016/S0261-5614(02)00214-5
  7. Jie B, Jiang ZM, Nolan MT, Zhu SN, Yu K, Kondrup J. Impact of preoperative nutritional support on clinical outcome in abdominal surgical patients at nutritional risk. Nutrition 2012;28:1022-7. https://doi.org/10.1016/j.nut.2012.01.017
  8. Biolo G. Protein metabolism and requirements. World Rev Nutr Diet 2013;105:12-20.
  9. Dickerson RN, Pitts SL, Maish GO 3rd, Schroeppel TJ, Magnotti LJ, Croce MA, et al. A reappraisal of nitrogen requirements for patients with critical illness and trauma. J Trauma Acute Care Surg 2012;73:549-57. https://doi.org/10.1097/TA.0b013e318256de1b
  10. Badjatia N, Monahan A, Carpenter A, Zimmerman J, Schmidt JM, Claassen J, et al. Inflammation, negative nitrogen balance, and outcome after aneurysmal subarachnoid hemorrhage. Neurology 2015;84;680-7. https://doi.org/10.1212/WNL.0000000000001259
  11. Peter JV, Moran JL, Phillips-Hughes J. A metaanalysis of treatment outcomes of early enteral versus early parenteral nutrition in hospitalized patients. Crit Care Med 2005;33:213-20; discussion 260-1. https://doi.org/10.1097/01.CCM.0000150960.36228.C0
  12. Heyland DK, Dhaliwal R, Drover JW, Gramlich L, Dodek P, Canadian Critical Care Clinical Practice Guidelines Committee. Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. JPEN J Parenter Enteral Nutr 2003;27:355-73. https://doi.org/10.1177/0148607103027005355
  13. Braunschweig CL, Levy P, Sheean PM, Wang X. Enteral compared with parenteral nutrition: a meta-analysis. Am J Clin Nutr 2001;74:534-42. https://doi.org/10.1093/ajcn/74.4.534
  14. Gramlich L, Kichian K, Pinilla J, Rodych NJ, Dhaliwal R, Heyland DK. Does enteral nutrition compared to parenteral nutrition result in better outcomes in critically ill adult patients? A systematic review of the literature. Nutrition 2004;20:843-8. https://doi.org/10.1016/j.nut.2004.06.003
  15. Moore FA, Feliciano DV, Andrassy RJ, McArdle AH, Booth FV, Morgenstein-Wagner TB, et al. Early enteral feeding, compared with parenteral, reduces postoperative septic complications. The results of a meta-analysis. Ann Surg 1992;216:172-83. https://doi.org/10.1097/00000658-199208000-00008
  16. Simpson F, Doig GS. Parenteral vs. enteral nutrition in the critically ill patient: a meta-analysis of trials using the intention to treat principle. Intensive Care Med 2005;31:12-23. https://doi.org/10.1007/s00134-004-2511-2
  17. Kudsk KA. Current aspects of mucosal immunology and its influence by nutrition. Am J Surg 2002;183:390-8. https://doi.org/10.1016/S0002-9610(02)00821-8
  18. Jabbar A, Chang WK, Dryden GW, McClave SA. Gut immunology and the differential response to feeding and starvation. Nutr Clin Pract 2003;18:461-82. https://doi.org/10.1177/0115426503018006461
  19. Windsor AC, Kanwar S, Li AG, Barnes E, Guthrie JA, Spark JI, et al. Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis. Gut 1998;42:431-5. https://doi.org/10.1136/gut.42.3.431
  20. National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, Rice TW, Wheeler AP, Thompson BT, Steingrub J, Hite RD, et al. Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial. JAMA 2012;307:795-803. https://doi.org/10.1001/jama.2012.137
  21. Doig GS, Heighes PT, Simpson F, Sweetman EA, Davies AR. Early enteral nutrition, provided within 24 h of injury or intensive care unit admission, significantly reduces mortality in critically ill patients: a meta-analysis of randomised controlled trials. Intensive Care Med 2009;35:2018-27. https://doi.org/10.1007/s00134-009-1664-4
  22. Stechmiller JK, Treloar D, Allen N. Gut dysfunction in critically ill patients: a review of the literature. Am J Crit Care 1997;6:204-9. https://doi.org/10.4037/ajcc1997.6.3.204
  23. Davies AR, Morrison SS, Bailey MJ, Bellomo R, Cooper DJ, Doig GS, et al. A multicenter, randomized controlled trial comparing early nasojejunal with nasogastric nutrition in critical illness. Crit Care Med 2012;40:2342-8. https://doi.org/10.1097/CCM.0b013e318255d87e
  24. Acosta-Escribano J, Fernandez-Vivas M, Grau Carmona T, Caturla-Such J, Garcia-Martinez M, Menendez-Mainer A, et al. Gastric versus transpyloric feeding in severe traumatic brain injury: a prospective, randomized trial. Intensive Care Med 2010;36:1532-9. https://doi.org/10.1007/s00134-010-1908-3
  25. Hsu CW, Sun SF, Lin SL, Kang SP, Chu KA, Lin CH, et al. Duodenal versus gastric feeding in medical intensive care unit patients: a prospective, randomized, clinical study. Crit Care Med 2009;37:1866-72. https://doi.org/10.1097/CCM.0b013e31819ffcda
  26. Kearns PJ, Chin D, Mueller L, Wallace K, Jensen WA, Kirsch CM. The incidence of ventilator-associated pneumonia and success in nutrient delivery with gastric versus small intestinal feeding: a randomized clinical trial. Crit Care Med 2000;28:1742-6. https://doi.org/10.1097/00003246-200006000-00007
  27. Montecalvo MA, Steger KA, Farber HW, Smith BF, Dennis RC, Fitzpatrick GF, et al. Nutritional outcome and pneumonia in critical care patients randomized to gastric versus jejunal tube feedings. The Critical Care Research Team. Crit Care Med 1992;20:1377-87. https://doi.org/10.1097/00003246-199210000-00004
  28. Montejo JC, Grau T, Acosta J, Ruiz-Santana S, Planas M, Garcia-De-Lorenzo A, et al. Multicenter, prospective, randomized, single-blind study comparing the efficacy and gastrointestinal complications of early jejunal feeding with early gastric feeding in critically ill patients. Crit Care Med 2002;30:796-800. https://doi.org/10.1097/00003246-200204000-00013
  29. Kortbeek JB, Haigh PI, Doig C. Duodenal versus gastric feeding in ventilated blunt trauma patients: a randomized controlled trial. J Trauma 1999;46:992-6; discussion 996-8. https://doi.org/10.1097/00005373-199906000-00002
  30. Taylor SJ, Fettes SB, Jewkes C, Nelson RJ. Prospective, randomized, controlled trial to determine the effect of early enhanced enteral nutrition on clinical outcome in mechanically ventilated patients suffering head injury. Crit Care Med 1999;27:2525-31. https://doi.org/10.1097/00003246-199911000-00033
  31. Minard G, Kudsk KA, Melton S, Patton JH, Tolley EA. Early versus delayed feeding with an immune-enhancing diet in patients with severe head injuries. JPEN J Parenter Enteral Nutr 2000;24:145-9. https://doi.org/10.1177/0148607100024003145
  32. Day L, Stotts NA, Frankfurt A, Stralovich-Romani A, Volz M, Muwaswes M, et al. Gastric versus duodenal feeding in patients with neurological disease: a pilot study. J Neurosci Nurs 2001;33:148-9,155-9. https://doi.org/10.1097/01376517-200106000-00007
  33. Davies AR, Froomes PR, French CJ, Bellomo R, Gutteridge GA, Nyulasi I, et al. Randomized comparison of nasojejunal and nasogastric feeding in critically ill patients. Crit Care Med 2002;30:586-90. https://doi.org/10.1097/00003246-200203000-00016
  34. White H, Sosnowski K, Tran K, Reeves A, Jones M. A randomised controlled comparison of early post-pyloric versus early gastric feeding to meet nutritional targets in ventilated intensive care patients. Crit Care 2009;13:R187. https://doi.org/10.1186/cc8181
  35. Heyland DK, Stephens KE, Day AG, McClave SA. The success of enteral nutrition and ICU-acquired infections: a multicenter observational study. Clin Nutr 2011;30:148-55. https://doi.org/10.1016/j.clnu.2010.09.011
  36. Montejo JC, Minambres E, Bordeje L, Mesejo A, Acosta J, Heras A, et al. Gastric residual volume during enteral nutrition in ICU patients: the REGANE study. Intensive Care Med 2010;36:1386-93. https://doi.org/10.1007/s00134-010-1856-y
  37. Pinilla JC, Samphire J, Arnold C, Liu L, Thiessen B. Comparison of gastrointestinal tolerance to two enteral feeding protocols in critically ill patients: a prospective, randomized controlled trial. JPEN J Parenter Enteral Nutr 2001;25:81-6. https://doi.org/10.1177/014860710102500281
  38. McClave SA, DeMeo MT, DeLegge MH, DiSario JA, Heyland DK, Maloney JP, et al. North American summit on aspiration in the critically Ill patient: consensus statement. JPEN J Parenter Enteral Nutr 2002;26(6 Suppl):S80-5. https://doi.org/10.1177/014860710202600613
  39. McClave SA, Lukan JK, Stefater JA, Lowen CC, Looney SW, Matheson PJ, et al. Poor validity of residual volumes as a marker for risk of aspiration in critically ill patients. Crit Care Med 2005;33:324-30. https://doi.org/10.1097/01.CCM.0000153413.46627.3A
  40. Reignier J, Mercier E, Le Gouge A, Boulain T, Desachy A, Bellec F, et al. Effect of not monitoring residual gastric volume on risk of ventilator-associated pneumonia in adults receiving mechanical ventilation and early enteral feeding: a randomized controlled trial. JAMA 2013;309:249-56. https://doi.org/10.1001/jama.2012.196377
  41. Powell KS, Marcuard SP, Farrior ES, Gallagher ML. Aspirating gastric residuals causes occlusion of small-bore feeding tubes. JPEN J Parenter Enteral Nutr 1993;17:243-6. https://doi.org/10.1177/0148607193017003243
  42. Kozar RA, McQuiggan MM, Moore EE, Kudsk KA, Jurkovich GJ, Moore FA. Postinjury enteral tolerance is reliably achieved by a standardized protocol. J Surg Res 2002;104:70-5. https://doi.org/10.1006/jsre.2002.6409
  43. Doig GS, Simpson F, Finfer S, Delaney A, Davies AR, Mitchell I, et al. Effect of evidence-based feeding guidelines on mortality of critically ill adults: a cluster randomized controlled trial. JAMA 2008;300:2731-41. https://doi.org/10.1001/jama.2008.826
  44. Barr J, Hecht M, Flavin KE, Khorana A, Gould MK. Outcomes in critically ill patients before and after the implementation of an evidence-based nutritional management protocol. Chest 2004;125:1446-57. https://doi.org/10.1378/chest.125.4.1446
  45. Heyland DK, Murch L, Cahill N, McCall M, Muscedere J, Stelfox HT, et al. Enhanced protein-energy provision via the enteral route feeding protocol in critically ill patients: results of a cluster randomized trial. Crit Care Med 2013;41:2743-53. https://doi.org/10.1097/CCM.0b013e31829efef5
  46. Spain DA, McClave SA, Sexton LK, Adams JL, Blanford BS, Sullins ME, et al. Infusion protocol improves delivery of enteral tube feeding in the critical care unit. JPEN J Parenter Enteral Nutr 1999;23:288-92. https://doi.org/10.1177/0148607199023005288
  47. Drakulovic MB, Torres A, Bauer TT, Nicolas JM, Nogue S, Ferrer M. Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomised trial. Lancet 1999;354:1851-8. https://doi.org/10.1016/S0140-6736(98)12251-1
  48. van Nieuwenhoven CA, Vandenbroucke-Grauls C, van Tiel FH, Joore HC, van Schijndel RJ, van der Tweel I, et al. Feasibility and effects of the semirecumbent position to prevent ventilator-associated pneumonia: a randomized study. Crit Care Med 2006;34:396-402. https://doi.org/10.1097/01.CCM.0000198529.76602.5E
  49. DeRiso AJ 2nd, Ladowski JS, Dillon TA, Justice JW, Peterson AC. Chlorhexidine gluconate 0.12% oral rinse reduces the incidence of total nosocomial respiratory infection and nonprophylactic systemic antibiotic use in patients undergoing heart surgery. Chest 1996;109:1556-61. https://doi.org/10.1378/chest.109.6.1556
  50. Houston S, Hougland P, Anderson JJ, LaRocco M, Kennedy V, Gentry LO. Effectiveness of 0.12% chlorhexidine gluconate oral rinse in reducing prevalence of nosocomial pneumonia in patients undergoing heart surgery. Am J Crit Care 2002;11:567-70. https://doi.org/10.4037/ajcc2002.11.6.567
  51. Ibrahim EH, Mehringer L, Prentice D, Sherman G, Schaiff R, Fraser V, et al. Early versus late enteral feeding of mechanically ventilated patients: results of a clinical trial. JPEN J Parenter Enteral Nutr 2002;26:174-81. https://doi.org/10.1177/0148607102026003174
  52. MacLeod JB, Lefton J, Houghton D, Roland C, Doherty J, Cohn SM, et al. Prospective randomized control trial of intermittent versus continuous gastric feeds for critically ill trauma patients. J Trauma 2007;63:57-61. https://doi.org/10.1097/01.ta.0000249294.58703.11
  53. Kollef MH. Prevention of hospital-associated pneumonia and ventilator-associated pneumonia. Crit Care Med 2004;32:1396-405. https://doi.org/10.1097/01.CCM.0000128569.09113.FB
  54. Heyland DK, Drover JW, MacDonald S, Novak F, Lam M. Effect of postpyloric feeding on gastroesophageal regurgitation and pulmonary microaspiration: results of a randomized controlled trial. Crit Care Med 2001;29:1495-501. https://doi.org/10.1097/00003246-200108000-00001
  55. Lien HC, Chang CS, Chen GH. Can percutaneous endoscopic jejunostomy prevent gastroesophageal reflux in patients with preexisting esophagitis? Am J Gastroenterol 2000;95:3439-43. https://doi.org/10.1111/j.1572-0241.2000.03281.x
  56. Chang SJ, Huang HH. Diarrhea in enterally fed patients: blame the diet? Curr Opin Clin Nutr Metab Care 2013;16:588-94. https://doi.org/10.1097/MCO.0b013e328363bcaf
  57. Maroo S, Lamont JT. Recurrent clostridium difficile. Gastroenterology 2006;130:1311-6. https://doi.org/10.1053/j.gastro.2006.02.044
  58. Consensus recommendations from the US summitt on immune-enhancing enteral therapy. JPEN J Parenter Enteral Nutr 2001;25(2 Suppl):S61-3. https://doi.org/10.1177/014860710102500213
  59. McIvor AC, Meguid MM, Curtas S, Warren J, Kaplan DS. Intestinal obstruction from cecal bezoar; a complication of fiber-containing tube feedings. Nutrition 1990;6:115-7.
  60. Scaife CL, Saffle JR, Morris SE. Intestinal obstruction secondary to enteral feedings in burn trauma patients. J Trauma 1999;47:859-63. https://doi.org/10.1097/00005373-199911000-00007
  61. Edes TE, Walk BE, Austin JL. Diarrhea in tube-fed patients: feeding formula not necessarily the cause. Am J Med 1990;88:91-3. https://doi.org/10.1016/0002-9343(90)90454-L
  62. Zhang Y, Chen J, Wu J, Chalson H, Merigan L, Mitchell A. Probiotic use in preventing postoperative infection in liver transplant patients. Hepatobiliary Surg Nutr 2013;2:142-7.
  63. Rayes N, Seehofer D, Muller AR, Hansen S, Bengmark S, Neuhaus P. Influence of probiotics and fibre on the incidence of bacterial infections following major abdominal surgery - results of a prospective trial. Z Gastroenterol 2002;40:869-76. https://doi.org/10.1055/s-2002-35259
  64. Rayes N, Seehofer D, Hansen S, Boucsein K, Muller AR, Serke S, et al. Early enteral supply of lactobacillus and fiber versus selective bowel decontamination: a controlled trial in liver transplant recipients. Transplantation 2002;74:123-7. https://doi.org/10.1097/00007890-200207150-00021
  65. Gu WJ, Deng T, Gong YZ, Jing R, Liu JC. The effects of probiotics in early enteral nutrition on the outcomes of trauma: a meta-analysis of randomized controlled trials. JPEN J Parenter Enteral Nutr 2013;37:310-7. https://doi.org/10.1177/0148607112463245
  66. Morrow LE, Kollef MH, Casale TB. Probiotic prophylaxis of ventilator-associated pneumonia: a blinded, randomized, controlled trial. Am J Respir Crit Care Med 2010;182:1058-64. https://doi.org/10.1164/rccm.200912-1853OC
  67. Bo L, Li J, Tao T, Bai Y, Ye X, Hotchkiss RS, et al. Probiotics for preventing ventilator-associated pneumonia. Cochrane Database Syst Rev 2014;25:CD009066.
  68. Li K, Zhang CF, Xia YH, Li ZJ, Han Y. Efficacy of probiotics on ulcerative colitis and its mechanism. Zhonghua Wei Chang Wai Ke Za Zhi 2013;16:336-9.
  69. Pattani R, Palda VA, Hwang SW, Shah PS. Probiotics for the prevention of antibiotic-associated diarrhea and Clostridium difficile infection among hospitalized patients: systematic review and meta-analysis. Open Med 2013;7:e56-67.
  70. Goldenberg JZ, Ma SS, Saxton JD, Martzen MR, Vandvik PO, Thorlund K, et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database Syst Rev 2013;5:CD006095.
  71. Garrel D, Patenaude J, Nedelec B, Samson L, Dorais J, Champoux J, et al. Decreased mortality and infectious morbidity in adult burn patients given enteral glutamine supplements: a prospective, controlled, randomized clinical trial. Crit Care Med 2003;31:2444-9. https://doi.org/10.1097/01.CCM.0000084848.63691.1E
  72. Houdijk AP, Rijnsburger ER, Jansen J, Wesdorp RI, Weiss JK, McCamish MA, et al. Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma. Lancet 1998;352:772-6. https://doi.org/10.1016/S0140-6736(98)02007-8
  73. Peng X, You ZY, Huang XK, Zhang CQ, He GZ, Xie WG, et al. Analysis of the therapeutic effect and the safety of glutamine granules per os in patients with severe burns and trauma. Zhonghua Shao Shang Za Zhi 2004;20:206-9.
  74. Zhou YP, Jiang ZM, Sun YH, Wang XR, Ma EL, Wilmore D. The effect of supplemental enteral glutamine on plasma levels, gut function, and outcome in severe burns: a randomized, double-blind, controlled clinical trial. JPEN J Parenter Enteral Nutr 2003;27:241-5. https://doi.org/10.1177/0148607103027004241
  75. Hall JC, Dobb G, Hall J, de Sousa R, Brennan L, McCauley R. A prospective randomized trial of enteral glutamine in critical illness. Intensive Care Med 2003;29:1710-6. https://doi.org/10.1007/s00134-003-1937-2
  76. Jones C, Palmer TE, Griffiths RD. Randomized clinical outcome study of critically ill patients given glutamine-supplemented enteral nutrition. Nutrition 1999;15:108-15. https://doi.org/10.1016/S0899-9007(98)00172-5
  77. Casaer MP, Mesotten D, Hermans G, Wouters PJ, Schetz M, Meyfroidt G, et al. Early versus late parenteral nutrition in critically ill adults. N Engl J Med 2011;365:506-17. https://doi.org/10.1056/NEJMoa1102662
  78. Heyland DK, MacDonald S, Keefe L, Drover JW. Total parenteral nutrition in the critically ill patient: a meta-analysis. JAMA 1998;280:2013-9. https://doi.org/10.1001/jama.280.23.2013
  79. Heidegger CP, Berger MM, Graf S, Zingg W, Darmon P, Costanza MC, et al. Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: a randomised controlled clinical trial. Lancet 2013;381:385-93. https://doi.org/10.1016/S0140-6736(12)61351-8
  80. Heyland DK. Early supplemental parenteral nutrition in critically ill adults increased infections, ICU length of stay and cost. Evid Based Med 2012;17:86-7. https://doi.org/10.1136/ebm.2011.100252
  81. Kutsogiannis J, Alberda C, Gramlich L, Cahill NE, Wang M, Day AG, et al. Early use of supplemental parenteral nutrition in critically ill patients: results of an international multicenter observational study. Crit Care Med 2011;39:2691-9. https://doi.org/10.1097/CCM.0b013e3182282a83
  82. Jonker MA, Hermsen JL, Sano Y, Heneghan AF, Lan J, Kudsk KA. Small intestine mucosal immune system response to injury and the impact of parenteral nutrition. Surgery 2012;151:278-86. https://doi.org/10.1016/j.surg.2010.10.013
  83. Jiang XH, Li N, Li JS. Intestinal permeability in patients after surgical trauma and effect of enteral nutrition versus parenteral nutrition. World J Gastroenterol 2003;9:1878-80. https://doi.org/10.3748/wjg.v9.i8.1878
  84. Lan J, Heneghan AF, Sano Y, Jonker MA, Omata J, Xu W, et al. Parenteral nutrition impairs lymphotoxin $\beta$ receptor signaling via NF-${\kappa}B$. Ann Surg 2011;253:996-1003. https://doi.org/10.1097/SLA.0b013e31821224eb
  85. O'Connor A, Hanly AM, Francis E, Keane N, McNamara DA. Catheter associated blood stream infections in patients receiving parenteral nutrition: a prospective study of 850 patients. J Clin Med Res 2013;5:18-21. https://doi.org/10.5897/JCMR11.041
  86. Todd SR, Gonzalez EA, Turner K, Kozar RA. Update on postinjury nutrition. Curr Opin Crit Care 2008;14:690-5. https://doi.org/10.1097/MCC.0b013e3283196562
  87. Hartl R, Gerber LM, Ni Q, Ghajar J. Effect of early nutrition on deaths due to severe traumatic brain injury. J Neurosurg 2008;109:50-6. https://doi.org/10.3171/JNS/2008/109/7/0050
  88. Chapple LS, Deane AM, Heyland DK, Lange K, Kranz AJ, Williams LT, et al. Energy and protein deficits throughout hospitalization in patients admitted with a traumatic brain injury. Clinical Nutrition 2016;35:1315-22. https://doi.org/10.1016/j.clnu.2016.02.009
  89. Foley N, Marshall S, Pikul J, Salter K, Teasell R. Hypermetabolism following moderate to severe traumatic acute brain injury: a systematic review. J Neurotrauma 2008;25:1415-31. https://doi.org/10.1089/neu.2008.0628
  90. Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons, Joint Section on Neurotrauma and Critical Care, AANS/CNS, Bratton SL, et al. Guidelines for the management of severe traumatic brain injury. XII. Nutrition. J Neurotrauma 2007;24 Suppl 1:S77-82. https://doi.org/10.1089/neu.2006.9984
  91. Koukiasa P, Bitzani M, Papaioannou V, Pnevmatikos I. Resting energy expenditure in critically ill patients with spontaneous intracranial hemorrhage. JPEN J Parenter Enteral Nutr 2015;39:917-21. https://doi.org/10.1177/0148607114539352
  92. Falcao de Arruda IS, de Aguilar-Nascimento JE. Benefits of early enteral nutrition with glutamine and probiotics in brain injury patients. Clin Sci (Lond) 2004;106:287-92. https://doi.org/10.1042/CS20030251
  93. Painter TJ, Rickerds J, Alban RF. Immune enhancing nutrition in traumatic brain injury - a preliminary study. Int J Surg 2015;21:70-4. https://doi.org/10.1016/j.ijsu.2015.07.008
  94. Hasadsri L, Wang BH, Lee JV, Erdman JW, Llano DA, Barbey AK, et al. Omega-3 fatty acids as a putative treatment for traumatic brain injury. J Neurotrauma 2013;30:897-906. https://doi.org/10.1089/neu.2012.2672
  95. Chen N, Li Y, Fang J, Lu Q, He L. Risk factors for malnutrition in stroke patients: a meta-analysis. Clin Nutr 2017;28:S0261-5614(17)31434-6.
  96. Ojo O, Brooke J. The use of enteral nutrition in the management of stroke. Nutrients 2016;8:E827. https://doi.org/10.3390/nu8120827
  97. Naito H, Nezu T, Hosomi N, Aoki S, Kinoshita N, Kuga J, et al. Controlling nutritional status score for predicting 3-mo functional outcome in acute ischemic stroke. Nutrition 2018;55-56:1-6. https://doi.org/10.1016/j.nut.2018.02.025
  98. Gomes F, Emery PW, Weekes CE. Risk of malnutrition is an independent predictor of mortality, length of hospital stay, and hospitalization costs in stroke patients. J Stroke Cerebrovasc Dis 2016;25:799-806. https://doi.org/10.1016/j.jstrokecerebrovasdis.2015.12.017
  99. Kim S, Byeon Y. Comparison of nutritional status indicators according to feeding methods in patients with acute stroke. Nutr Neurosci 2014;17:138-44. https://doi.org/10.1179/1476830513Y.0000000078
  100. Nishioka S, Okamoto T, Takayama M, Urushihara M, Watanabe M, Kiriya Y, et al. Malnutrition risk predicts recovery of full oral intake among older adult stroke patients undergoing enteral nutrition: secondary analysis of a multicentre survey (the APPLE study). Clin Nutr 2017;36:1089-96. https://doi.org/10.1016/j.clnu.2016.06.028
  101. Nii M, Maeda K, Wakabayashi H, Nishioka S, Tanaka A. Nutritional improvement and energy intake are associated with functional recovery in patients after cerebrovascular disorders. J Stroke Cerebrovasc Dis 2016;25:57-62. https://doi.org/10.1016/j.jstrokecerebrovasdis.2015.08.033
  102. Kokura Y, Maeda K, Wakabayashi H, Nishioka S, Higashi S. High nutritional-related risk on admission predicts less improvement of functional independence measure in geriatric stroke patients: a retrospective cohort study. J Stroke Cerebrovasc Dis 2016;25:1335-41. https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.01.048
  103. Maruyama K, Nakagawa N, Koyama S, Maruyama JI, Hasebe N. Malnutrition increases the incidence of death, cardiovascular events, and infections in patients with stroke after rehabilitation. J Stroke Cerebrovasc Dis 2018;27:716-23. https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.10.002

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