Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
권호 표지
DOI QR코드

DOI QR Code

A Case Report of Male Occult Breast Cancer Manifested as Superior Vena Cava Syndrome

상대 정맥 증후군으로 발현된 남성 잠재성 유방암의 증례 보고

  • Kang, Hyein (Department of Radiology, Chung-Ang University Medical Center) ;
  • Ha, Su Min (Department of Radiology and Thyroid Center, Chung-Ang University Medical Center) ;
  • Ahn, Hye Shin (Department of Radiology and Thyroid Center, Chung-Ang University Medical Center) ;
  • Kim, Hee Sung (Department of Pathology, Chung-Ang University Medical Center) ;
  • Kim, Hee-Jun (Department of Internal Medicine, Chung-Ang University Medical Center)
  • 강혜인 (중앙대학교병원 영상의학과) ;
  • 하수민 (중앙대학교병원 영상의학과 유방 갑상선센터) ;
  • 안혜신 (중앙대학교병원 영상의학과 유방 갑상선센터) ;
  • 김희성 (중앙대학교병원 병리과) ;
  • 김희준 (중앙대학교병원 혈액종양내과)
  • Received : 2018.02.06
  • Accepted : 2018.05.22
  • Published : 2018.10.01
⟨ Previous Next ⟩

Abstract

Occult breast cancer (OBC) is an asymptomatic condition. We report a case of OBC in a 72-year-old male patient who presented with severe dyspnea and upper extremity swelling. Computed tomography scan showed multiple lymph node enlargements in the supraclavicular and infraclavicular areas, and ultrasound scan showed multiple axillary lymph node enlargements. Based on the radiological findings, clinicians suspected lymphoma or disseminated metastasis from unknown primary malignancies. However, the axillary biopsy specimen revealed invasive breast cancer with hormonal receptor positivity.

잠재성 유방암은 유방에 어떠한 증상없이 발생하는 유방암의 한 종류를 칭한다. 우리는 심한 호흡곤란과 상지부종을 보였던 72세 남성환자의 잠재성 유방암 증례를 보고한다. 전산화단층촬영에서는 양측 쇄골상 및 쇄골하 부위의 다수의 림프절 종대가 보였고 초음파 검사상 여러 개의 액와 림프절 종대가 발견되었다. 영상의학적 소견으로부터 임상의들은 림프종이나 불명의 원발성 암종의 파종성 전이를 의심했다. 액와 생검 표본으로부터 호르몬수용체 양성의 침윤성 유방암임이 밝혀졌다.

Keywords

References

  1. Sasco AJ, Lowenfels AB, Pasker-de Jong P. Review article: epidemiology of male breast cancer. A meta-analysis of published case-control studies and discussion of selected aetiological factors. Int J Cancer 1993;53:538-549
  2. Chen L, Chantra PK, Larsen LH, Barton P, Rohitopakarn M, Zhu EQ, et al. Imaging characteristics of malignant lesions of the male breast. Radiographics 2006;26:993-1006
  3. Baron PL, Moore MP, Kinne DW, Candela FC, Osborne MP, Petrek JA. Occult breast cancer presenting with axillary metastases. Updated management. Arch Surg 1990;125:210-214
  4. Weiss JR, Moysich KB, Swede H. Epidemiology of male breast cancer. Cancer Epidemiol Biomarkers Prev 2005;14: 20-26
  5. Burga AM, Fadare O, Lininger RA, Tavassoli FA. Invasive carcinomas of the male breast: a morphologic study of the distribution of histologic subtypes and metastatic patterns in 778 cases. Virchows Arch 2006;449:507-512
  6. Giordano SH. A review of the diagnosis and management of male breast cancer. Oncologist 2005;10:471-479
  7. He M, Liu H, Jiang Y. A Case report of male occult breast cancer first manifesting as axillary lymph node metastasis with part of metastatic mucinous carcinoma. Medicine (Baltimore) 2015;94:e1038
  8. Sohn G, Son BH, Lee SJ, Kang EY, Jung SH, Cho SH, et al. Treatment and survival of patients with occult breast cancer with axillary lymph node metastasis: a nationwide retrospective study. J Surg Oncol 2014;110:270-274
  9. Leonard RC, Mansi JL, Keerie C, Yellowlees A, Crawford S, Benstead K, et al. A randomised trial of secondary prophylaxis using granulocyte colony-stimulating factor ('sprog' trial) for maintaining dose intensity of standard adjuvant chemotherapy for breast cancer by the anglo-celtic cooperative group and ncrn. Ann Oncol 2015;26:2437-2441
  10. Hur SM, Cho DH, Lee SK, Choi MY, Bae SY, Koo MY, et al. Occult breast cancers manifesting as axillary lymph node metastasis in men: a two-case report. J Breast Cancer 2012; 15:359-363