DOI QR코드

DOI QR Code

식도종격동누공을 형성한 결핵 종격동 림프절염 1예

Esophago-Mediastinal Fistula Due to Tuberculous Mediastinal Lymphadenitis

  • 김진영 (울산대학교 의과대학 서울아산병원 내과) ;
  • 김호연 (울산대학교 의과대학 서울아산병원 내과) ;
  • 이형경 (울산대학교 의과대학 서울아산병원 내과) ;
  • 정민선 (울산대학교 의과대학 서울아산병원 내과) ;
  • 형례창 (울산대학교 의과대학 서울아산병원 내과) ;
  • 김도훈 (울산대학교 의과대학 서울아산병원 소화기내과) ;
  • 정훈용 (울산대학교 의과대학 서울아산병원 소화기내과)
  • Kim, Jinyoung (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Hoyun (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Hyeungkyeung (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Cheong, Minseon (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Hsing, Li Chang (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Do Hoon (Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jung, Hwoon-Yong (Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine)
  • 투고 : 2017.04.12
  • 심사 : 2017.09.04
  • 발행 : 2018.10.01

초록

결핵의 식도 침범 및 이의 합병증인 식도종격동누공 형성은 매우 드물고 국내 보고가 거의 없다. 대부분 종격동 림프절염에서 식도 침범이 이루어지고 이러한 경우 식도종격동누공을 형성할 수 있다. 저자들은 식도종격동누공 치료에 내시경적 클립 결찰술을 먼저 시도하였으나 누공 폐쇄에 실패하였고, 경피적 내시경 위루술을 통한 항결핵제 치료만으로 누공 폐쇄를 경험하였기에 보고한다.

Tuberculosis rarely involves the esophagus, and most esophageal tuberculosis occurs secondary to adjacent tuberculous lymphadenitis. An esophago-mediastinal fistula is a very unusual complication of tuberculous lymphadenitis. Herein, we report a case of an esophago-mediastinal fistula due to tuberculous lymphadenitis. A 28-year-old woman who had dysphagia was assessed by chest computed tomography, endoscopy, esophagogram, and a lymph node biopsy. An esophago-mediastinal fistula was found and an antituberculous agent was considered initially. However, because of her severe dysphagia, she managed with endoscopic clipping as an alternative. However, the fistula remained on follow-up esophagography. A gastrostomy was eventually performed, and she was treated with an antituberculous agent. The fistula had closed after 4 weeks of medication. Antituberculous agents are the mainstay treatment for esophago-mediastinal fistula due to tuberculous lymphadenitis; endoscopic clipping may be a complementary treatment.

키워드

참고문헌

  1. Lockard LB. Esophageal tuberculosis; a critical review. Laryngoscope 1913;23:561-584.
  2. Mokoena T, Shama DM, Ngakane H, Bryer JV. Oesophageal tuberculosis: a review of eleven cases. Postgrad Med J 1992;68:110-115. https://doi.org/10.1136/pgmj.68.796.110
  3. Devarbhavi HC, Alvares JF, Radhikadevi M. Esophageal tuberculosis associated with esophagotracheal or esophagomediastinal fistula: report of 10 cases. Gastrointest Endosc 2003;57:588-592. https://doi.org/10.1067/mge.2003.140
  4. Williford ME, Thompson WM, Hamilton JD, Postlethwait RW. Esophageal tuberculosis: findings on barium swallow and computed tomography. Gastrointest Radiol 1983;8:119-122. https://doi.org/10.1007/BF01948102
  5. Moon WK, Im JG, Yeon KM, Han MC. Mediastinal tuberculous lymphadenitis: CT findings of active and inactive disease. AJR Am J Roentgenol 1998;170:715-718. https://doi.org/10.2214/ajr.170.3.9490959
  6. Im JG, Kim JH, Han MC, Kim CW. Computed tomography of esophagomediastinal fistula in tuberculous mediastinal lymphadenitis. J Comput Assist Tomogr 1990;14:89-92. https://doi.org/10.1097/00004728-199001000-00015
  7. Damtew B, Frengley D, Wolinsky E, Spagnuolo PJ. Esophageal tuberculosis: mimicry of gastrointestinal malignancy. Rev Infect Dis 1987;9:140-146. https://doi.org/10.1093/clinids/9.1.140
  8. Jain S, Jain S, Jain M, Yaduvanshi A. Esophageal tuberculosis: is it so rare? Report of 12 cases and review of the literature. Am J Gastroenterol 2002;97:287-291. https://doi.org/10.1111/j.1572-0241.2002.05456.x
  9. Albuquerque A, Nunes ACR, Azevedo F, Macedo G. Successful closure of unusual tuberculous esophagomediastinal fistula with endoscopic clips. GE Port J Gastroenterol 2013;20:219-221.