Warthin씨 종양에서 발생한 편평상피암 1예

A Case of Squamous Cell Carcinoma Arising in a Warthin's Tumor

  • 손정협 (인제대학교 의과대학 상계백병원 이비인후과학교실) ;
  • 조경래 (인제대학교 의과대학 상계백병원 이비인후과학교실)
  • Sohn, Jung Heob (Departments of Otorhinolaryngology-Head and Neck Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Cho, Kyoung Rai (Departments of Otorhinolaryngology-Head and Neck Surgery, Sanggye Paik Hospital, College of Medicine, Inje University)
  • 투고 : 2018.09.17
  • 심사 : 2018.11.30
  • 발행 : 2018.12.30

초록

Warthin's tumor is the second most common benign tumor of the parotid gland, which consists of epithelial and lymphoid components. Malignant change is known to be extremely rare. In Korean literature, only a case of low grade adenocarcinoma arising from Warthin's tumor was reported. For squamous cell carcinoma, there has never been reported in Korea. The authors report a case of squamous cell carcinoma arising from Warthin's tumor in a 77-year-old male, who was treated with primary resection. The patient is well without any recurrence or metastasis after 15 months of follow-up.

키워드

참고문헌

  1. Gunduz M, Yamanaka N, Hotomi M, Kuki K, Yokoyama M, Nakamine H. Squamous cell carcinoma arising in a Warthin's tumor. Auris Nasus Larynx 1999;26(3):355-60. https://doi.org/10.1016/S0385-8146(99)00008-5
  2. Lee KD, Lee HS, Mun HS, Heu B. A case of polymorphous low grade adenocarcinoma arising from Warthin's tumor. Korean J Otolaryngol 2006;49(2):232-5.
  3. Lim S, Ryu S, Lee K, Hwang B, Lee EJ, Hong KH, et al. A clinical study of the Warthin's tumor of the salivary gland. Korean J Otorhinolaryngol-Head Neck Surg 2011;54(3):213-6. https://doi.org/10.3342/kjorl-hns.2011.54.3.213
  4. Batsakis JG, Regezi JA, Bloch D. The pathology of the head and neck tumors: salivary glands, part 3. Hea Neck Surg 1979;1(3):260-73. https://doi.org/10.1002/hed.2890010310
  5. Cob CJ, Greaves TS, Raza AS. Fine needle aspiration cytology and the diagnostic pitfalls in Warthin's tumour with necrotizing granulomatous inflammation and facial nerve paralysis. Acta Cytol. 2009;53(4):431-4. https://doi.org/10.1159/000325346
  6. Yaranal PJ, T U. Squamous Cell Carcinoma Arising in Warthin's Tumour: A Case Report. J Clin Diagn Res 2013;7(1):163-5.
  7. Yoo GH, Eisele DW, Askin FB, Driben JS, Johns ME. Warthin's tu-mor: a 40-year experience at The Johns Hopkins Hospital. Laryngoscope 1994;104(7):799-803.
  8. Choi G, Kim HY, Park HJ, Woo JS, Jung KY, Choi JO. Clinical study of Warthin's tumors. Korean J Otolaryngol-Head Neck Surg 1996;39 (11):1820-7.
  9. Choi JO, Ju EJ, Kim WJ, Choi HY, Chu HR, Choi G, et al. Selection of surgical treatment for Warthin's tumor of parotid: experience in 20 cases. Korean J Otolaryngol-Head Neck Surg 1999;42(4):501-4.
  10. Williamson JD, Simmons BH, El-Naggar A, Medeiros LJ. Mucoepidermoid carcinoma involving Warthin tumor. A report of five cases and review of the literature. Am J Clin Pathol 2000;114(4):564-70. https://doi.org/10.1309/GUT1-F58A-V4WV-0D8P
  11. Seifert G. Bilateral mucoepidermoid carcinomas arising in bilateral pre-existing Warthin's tumors of the parotid gland. Oral Oncol 1997;33(4):284-7. https://doi.org/10.1016/S0964-1955(97)00018-3
  12. Sayar H, Oztarakci H, Sayar C, Agirbas S. Adenocarcinoma arising in Warthin tumor of the parotid gland. Turk Patoloji Derg 2012;28(3):278-81.
  13. Damjanov I, Sneff EM, Delerme AN. Squamous cell carcinoma arising in unilateral Warthin's tumour of the parotid gland; A light electron microscopic and immunohistochemical study. Oral Surg Oral Med Oral Pathol 1983;55(3):286-90. https://doi.org/10.1016/0030-4220(83)90329-8
  14. Jecker P, Hartwein J. Metastasis to the parotid gland: is a radical surgical approach justified? Am J Otolaryngol 1996;17(2):102-5. https://doi.org/10.1016/S0196-0709(96)90004-6
  15. McClatchey KD, Appelblat NH, Langin JL. Carcinoma in papillary cystadenoma lymphomatosum (Warthin's tumor). Laryngoscope 1982;92(1):98-9.
  16. Sharama M, Chintamani, Saxena S, Agrawal S. Squamous cell carcinoma arising in unilateral Warthin's tumour of the parotid gland. J Oral Maxillofacial Pathol 2008;12:82-4. https://doi.org/10.4103/0973-029X.44585
  17. Seifert G, Bull HG, Donath K. Histologic subclassification of the cystadenolymphoma of the parotid gland. Analysis of 275 cases. Virchows Arch A Pathol Anat Histol 1980;388(1):13-38. https://doi.org/10.1007/BF00430674