Journal of Clinical Otolaryngology Head and Neck Surgery (임상이비인후과)

The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery (대한이비인후과학회 부산,울산,경남 지부회)
권호 표지

A Case of Atypical Lipomatous Tumor of the Neck

경부에서 발견된 비정형 지방종성 종양 1예

  • Loh, Young Jin (Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine) ;
  • Lee, Dong Kun (Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine) ;
  • Park, Heon Soo (Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine)
  • 노영진 (동아대학교 의과대학 이비인후-두경부외과학교실) ;
  • 이동근 (동아대학교 의과대학 이비인후-두경부외과학교실) ;
  • 박헌수 (동아대학교 의과대학 이비인후-두경부외과학교실)
  • Received : 2018.08.03
  • Accepted : 2018.11.27
  • Published : 2018.12.30

⟨ Previous Next ⟩

Abstract

Liposarcoma is a malignant tumor that occurs in adipocytes, accounting for 5% of all sarcomas. Generally, it has no symptoms and it occurs in any parts of the body. There are various types of liposarcoma. Of these, 40-45% are known as highly differentiated liposarcoma, and highly differentiated liposarcoma is also referred to as atypical lipomatous tumor. We report a case of an atypical lipomatous tumor on the left neck.

Keywords

References

  1. Dei Tos AP. Liposarcoma: New entities and evolving concepts. Ann Diagn Pathol 2000;4(4):252-66. https://doi.org/10.1053/adpa.2000.8133
  2. Sirvent N, Forus A, Lescaut W, Burel F, Benzaken S, Chazal M, et al. Characterization of centromere alterations in liposarcomas. Genes Chromosomes Cancer 2000;29(2):117-29. https://doi.org/10.1002/1098-2264(2000)9999:9999<::AID-GCC1014>3.0.CO;2-Q
  3. Enzinger FM. Liposarcoma. A study of 103 cases. Virchows Arch Pathol Anat 1962;335:367-88. https://doi.org/10.1007/BF00957030
  4. Kim YB, Leem DH, Baek JA, Ko SO. Atypical lipomatous tumor/well-differentiated liposarcoma of the gingiva: a case report and review of literature. J Oral Maxillofac Surg 2014;72(2):431-9. https://doi.org/10.1016/j.joms.2013.06.222
  5. Dei Tos AP, Mentzel T, Newman PL, Fletcher CD. Spindle cell liposarcoma, a hitherto unrecognized variant of liposarcoma. Analysis of six cases. Am J Surg Pathol 1994;18(9):913-21. https://doi.org/10.1097/00000478-199409000-00006
  6. Suster S, Wong TY, Moran CA. Sarcomas with combined features of liposarcoma and leiomyosarcoma. Study of two cases of an unusual soft-tissue tumor showing dual lineage differentiation. Am J Surg Pathol 1993;17(9):905-11. https://doi.org/10.1097/00000478-199309000-00006
  7. Dei Tos AP, Wadden C, Fletcher CD. S-100 protein staining in liposarcoma. Its diagnostic utility in the high grade myxoid (round cell) variant. Appl Immunohistochem 1996;4:95-101.
  8. Binh MB, Sastre-Garau X, Guillou L, de Pinieux G, Terrier P, Lagace R, et al. MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes. A comparative analysis of 559 soft tissue neoplasms with genetic data. Am J Surg Pathol 2005;29(10):1340-47. https://doi.org/10.1097/01.pas.0000170343.09562.39
  9. Kooby DA, Antonescu CR, Brennan MF, Singer S. Atypical lipomatous tumor/well-differentiated liposarcoma of the extremity and trunk wall: Importance of histological subtype with treatment recommendations. Ann Surg Oncol 2004;11(1):78-84. https://doi.org/10.1007/BF02524350
  10. Rosai J, Akerman M, Dal Cin P, DeWever I, Fletcher CD, Mandahl N, et al. Combined morphologic and karyotypic study of 59 atypical lipomatous tumors. Evaluation of their relationship and differential diagnosis with other adipose tissue tumors (a report of the CHAMP Study Group). Am J Surg Pathol 1996;20(10):1182-9. https://doi.org/10.1097/00000478-199610000-00002
  11. Evans HL. Atypical lipomatous tumor, its variants, and its combined forms: a study of 61 cases, with a minimum follow-up of 10 years. Am J Surg Pathol 2007;31(1):1-14. https://doi.org/10.1097/01.pas.0000213406.95440.7a