Perinatology

The Korean Society of Perinatology (대한주산의학회)
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Efficacy of Serum Neutrophil-to-Lymphocyte Ratio for Meconium Aspiration Syndrome

  • Jo, Chae-Ku (Department of Pediatrics, Dong-A University College of Medicine) ;
  • Kang, Sung-Min (Department of Pediatrics, Dong-A University College of Medicine) ;
  • Lee, Sun-Young (Department of Pediatrics, Dong-A University College of Medicine) ;
  • Kim, Myo-Jing (Department of Pediatrics, Dong-A University College of Medicine)
  • Received : 2017.06.13
  • Accepted : 2018.08.26
  • Published : 2018.12.31
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Abstract

Objective: To evaluate the relationship between serum neutrophil-to-lymphocyte ratio (NLR) and severity of meconium aspiration syndrome (MAS). Methods: We retrospectively analyzed 197 neonates who admitted for MAS between 2008 and 2016 at the neonatal intensive care unit of Dong-A University Hospital. The serial changes of NLR were analyzed from 1st to 3rd day of life. The NLR was compared by disease severities (non-invasive respiratory care group vs. invasive respiratory care group and MAS with or without persistent pulmonary hypertension of the newborn [PPHN]). Results: The NLR values from 1st to 3rd day of life significantly increased and then decreased (P=0.031). The NLR of invasive respiratory care group was significantly higher than non-invasive respiratory care group at 2nd, 3rd, and average of 1 to 3 days of life. The NLR of PPHN group was significantly higher than without PPHN group at 3rd, and average of 1 to 3 days of life. Conclusion: The NLR was significantly increased and then decreased in early stage of MAS and associated with the severity of MAS.

Keywords

References

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