DOI QR코드

DOI QR Code

Transanal Tube Drainage as a Conservative Treatment for Anastomotic Leakage Following a Rectal Resection

  • Shalaby, Mostafa (Department of General Surgery, Policlinico Tor Vergata Hospital, University of Rome Tor Vergata) ;
  • Thabet, Waleed (Department General Surgery, Mansoura University Hospitals, Mansoura University) ;
  • Buonomo, Oreste (Department of General Surgery, Policlinico Tor Vergata Hospital, University of Rome Tor Vergata) ;
  • Di Lorenzo, Nicola (Department of General Surgery, Policlinico Tor Vergata Hospital, University of Rome Tor Vergata) ;
  • Morshed, Mosaad (Department General Surgery, Mansoura University Hospitals, Mansoura University) ;
  • Petrella, Giuseppe (Department of General Surgery, Policlinico Tor Vergata Hospital, University of Rome Tor Vergata) ;
  • Farid, Mohamed (Department General Surgery, Mansoura University Hospitals, Mansoura University) ;
  • Sileri, Pierpaolo (Department of General Surgery, Policlinico Tor Vergata Hospital, University of Rome Tor Vergata)
  • 투고 : 2017.07.20
  • 심사 : 2017.10.18
  • 발행 : 2018.12.31

초록

Purpose: We evaluate the role of transanal tube drainage (TD) as a conservative treatment for patients with anastomotic leakage (AL). Methods: Patients treated for AL who had undergone a low or an ultralow anterior resection with colorectal or coloanal anastomosis for the treatment of rectal cancer between January 2013 and January 2017 were enrolled in this study. The data were collected prospectively and analyzed retrospectively. The primary outcomes were the diagnosis and the management of AL. Results: Two hundred thirteen consecutive patients, 122 males and 91 females, were included. The mean age was $66.91{\pm}11.15years$, and the median body mass index was $24kg/m^2$ (range, $20-35kg/m^2$). The median tumor distance from the anal verge was 8 cm (range, 4-12 cm). Ninety-three patients (44%) received neoadjuvant therapy for nodal disease and/or locally advanced rectal cancer. Only 13 patients (6%) developed AL. Six patients developed subclinical AL as they had a defunctioning ileostomy at the time of the initial procedure. They were treated conservatively with TD under endoscopic guidance in the endoscopy unit and received intravenous antibiotics. Six weeks after discharge, these 6 patients underwent follow-up flexible sigmoidoscopy which showed a completely healed anastomotic defect with no residual stenosis. Seven patients developed a clinically significant AL and required reoperation with pelvic abscess drainage and Hartmann colostomy formation. Conclusion: These results suggest that TD for management of patients with AL is safe, cheap, and effective. Salvaging the anastomosis will help decrease the need for Hartmann colostomy formation. Proper patient selection is important.

키워드

참고문헌

  1. Sakr A, Emile SH, Abdallah E, Thabet W, Khafagy W. Predictive factors for small intestinal and colonic anastomotic leak: a multivariate analysis. Indian J Surg 2017;79:555-62. https://doi.org/10.1007/s12262-016-1556-0
  2. Phitayakorn R, Delaney CP, Reynolds HL, Champagne BJ, Heriot AG, Neary P, et al. Standardized algorithms for management of anastomotic leaks and related abdominal and pelvic abscesses after colorectal surgery. World J Surg 2008;32:1147-56. https://doi.org/10.1007/s00268-008-9468-1
  3. Daams F, Luyer M, Lange JF. Colorectal anastomotic leakage: aspects of prevention, detection and treatment. World J Gastroenterol 2013;19:2293-7. https://doi.org/10.3748/wjg.v19.i15.2293
  4. Vallance A, Wexner S, Berho M, Cahill R, Coleman M, Haboubi N, et al. A collaborative review of the current concepts and challenges of anastomotic leaks in colorectal surgery. Colorectal Dis 2017;19:O1-12. https://doi.org/10.1111/codi.13534
  5. Soeters PB, de Zoete JP, Dejong CH, Williams NS, Baeten CG. Colorectal surgery and anastomotic leakage. Dig Surg 2002;19: 150-5. https://doi.org/10.1159/000052031
  6. Blumetti J, Abcarian H. Management of low colorectal anastomotic leak: Preserving the anastomosis. World J Gastrointest Surg 2015;7:378-83. https://doi.org/10.4240/wjgs.v7.i12.378
  7. Krarup PM, Jorgensen LN, Harling H; Danish Colorectal Cancer Group. Management of anastomotic leakage in a nationwide cohort of colonic cancer patients. J Am Coll Surg 2014;218:940-9. https://doi.org/10.1016/j.jamcollsurg.2014.01.051
  8. Longo WE, Milsom JW, Lavery IC, Church JC, Oakley JR, Fazio VW. Pelvic abscess after colon and rectal surgery--what is optimal management? Dis Colon Rectum 1993;36:936-41. https://doi.org/10.1007/BF02050629
  9. Lindgren R, Hallbook O, Rutegard J, Sjodahl R, Matthiessen P. What is the risk for a permanent stoma after low anterior resection of the rectum for cancer? A six-year follow-up of a multicenter trial. Dis Colon Rectum 2011;54:41-7. https://doi.org/10.1007/DCR.0b013e3181fd2948
  10. Edden Y, Weiss EG. Surgical considerations in anastomotic dehiscence. In: Zbar AP, Madoff RD, Wexner SD, editors. Reconstructive surgery of the rectum, anus and perineum. London: Springer; 2013. p. 511-6.
  11. Thorson AG, Thompson JS. Transrectal drainage of anastomotic leaks following low colonic anastomosis. Dis Colon Rectum 1984; 27:492-4. https://doi.org/10.1007/BF02555554
  12. Xiao L, Zhang WB, Jiang PC, Bu XF, Yan Q, Li H, et al. Can transanal tube placement after anterior resection for rectal carcinoma reduce anastomotic leakage rate? A single-institution prospective randomized study. World J Surg 2011;35:1367-77. https://doi.org/10.1007/s00268-011-1053-3
  13. Heald RJ. A new approach to rectal cancer. Br J Hosp Med 1979;22:277-81.
  14. Rahbari NN, Weitz J, Hohenberger W, Heald RJ, Moran B, Ulrich A, et al. Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer. Surgery 2010;147:339-51. https://doi.org/10.1016/j.surg.2009.10.012
  15. Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AM, et al. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. Lancet 2005; 365:1718-26. https://doi.org/10.1016/S0140-6736(05)66545-2
  16. Park IJ, Choi GS, Lim KH, Kang BM, Jun SH. Laparoscopic resection of extraperitoneal rectal cancer: a comparative analysis with open resection. Surg Endosc 2009;23:1818-24. https://doi.org/10.1007/s00464-008-0265-6
  17. Kim SH, Park IJ, Joh YG, Hahn KY. Laparoscopic resection for rectal cancer: a prospective analysis of thirty-month follow-up outcomes in 312 patients. Surg Endosc 2006;20:1197-202. https://doi.org/10.1007/s00464-005-0599-2
  18. van der Pas MH, Haglind E, Cuesta MA, Furst A, Lacy AM, Hop WC, et al. Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial. Lancet Oncol 2013;14:210-8. https://doi.org/10.1016/S1470-2045(13)70016-0
  19. Morino M, Parini U, Giraudo G, Salval M, Brachet Contul R, Garrone C. Laparoscopic total mesorectal excision: a consecutive series of 100 patients. Ann Surg 2003;237:335-42.
  20. Miyajima N, Fukunaga M, Hasegawa H, Tanaka J, Okuda J, Watanabe M, et al. Results of a multicenter study of 1,057 cases of rectal cancer treated by laparoscopic surgery. Surg Endosc 2009;23: 113-8. https://doi.org/10.1007/s00464-008-0078-7
  21. Karanjia ND, Corder AP, Holdsworth PJ, Heald RJ. Risk of peritonitis and fatal septicaemia and the need to defunction the low anastomosis. Br J Surg 1991;78:196-8. https://doi.org/10.1002/bjs.1800780221
  22. Kornmann VN, Treskes N, Hoonhout LH, Bollen TL, van Ramshorst B, Boerma D. Systematic review on the value of CT scanning in the diagnosis of anastomotic leakage after colorectal surgery. Int J Colorectal Dis 2013;28:437-45. https://doi.org/10.1007/s00384-012-1623-3
  23. Sirois-Giguere E, Boulanger-Gobeil C, Bouchard A, Gagne JP, Gregoire RC, Thibault C, et al. Transanal drainage to treat anastomotic leaks after low anterior resection for rectal cancer: a valuable option. Dis Colon Rectum 2013;56:586-92. https://doi.org/10.1097/DCR.0b013e31827687a4
  24. Brent A, Armstrong T, Nash GF, Heald RJ. Therapeutic use of the Heald Silastic Anal Stent. Colorectal Dis 2007;9:279-80. https://doi.org/10.1111/j.1463-1318.2006.01165.x
  25. Cook EJ, Moran BJ, Heald RJ, Nash GF. Pelvic collection drainage by Heald anal stent. Ann R Coll Surg Engl 2012;94:361. https://doi.org/10.1308/rcsann.2012.94.5.361
  26. Kamocka A, Skipper D. Drainage of a pelvic collection with the Heald Silastic Anal Stent. Colorectal Dis 2010;12:485-6. https://doi.org/10.1111/j.1463-1318.2009.02085.x
  27. Lee SY, Kim CH, Kim YJ, Kim HR. Impact of anal decompression on anastomotic leakage after low anterior resection for rectal cancer: a propensity score matching analysis. Langenbecks Arch Surg 2015;400:791-6. https://doi.org/10.1007/s00423-015-1336-5
  28. Wang S, Zhang Z, Liu M, Li S, Jiang C. Efficacy of transanal tube placement after anterior resection for rectal cancer: a systematic review and meta-analysis. World J Surg Oncol 2016;14:92. https://doi.org/10.1186/s12957-016-0854-0
  29. Ha GW, Kim HJ, Lee MR. Transanal tube placement for prevention of anastomotic leakage following low anterior resection for rectal cancer: a systematic review and meta-analysis. Ann Surg Treat Res 2015;89:313-8. https://doi.org/10.4174/astr.2015.89.6.313
  30. Tan WS, Tang CL, Shi L, Eu KW. Meta-analysis of defunctioning stomas in low anterior resection for rectal cancer. Br J Surg 2009; 96:462-72. https://doi.org/10.1002/bjs.6594

피인용 문헌

  1. Preventive strategies for anastomotic leakage after colorectal resections: A review vol.7, pp.8, 2018, https://doi.org/10.13105/wjma.v7.i8.389
  2. Long-Term Results after Anastomotic Leakage following Rectal Cancer Surgery: A Comparison of Treatment with Endo-Sponge and Transanal Irrigation vol.37, pp.6, 2018, https://doi.org/10.1159/000508935
  3. Improved colorectal anastomotic leakage healing by transanal rinsing treatment after endoscopic vacuum therapy using a novel patient-applied rinsing catheter vol.35, pp.1, 2020, https://doi.org/10.1007/s00384-019-03456-2
  4. Surgical complications in colorectal cancer patients vol.55, pp.None, 2018, https://doi.org/10.1016/j.amsu.2020.04.024
  5. Percutaneous transesophageal gastro-tubing for the management of anastomotic leakage after upper GI surgery: a report of two clinical cases vol.6, pp.1, 2018, https://doi.org/10.1186/s40792-020-00965-z
  6. The usefulness of transanal tube for reducing anastomotic leak in mid rectal cancer: compared to diverting stoma vol.100, pp.2, 2018, https://doi.org/10.4174/astr.2021.100.2.100
  7. Retrospective study of active drainage in the management of anastomotic leakage after anterior resection for rectal cancer vol.49, pp.12, 2021, https://doi.org/10.1177/03000605211065942