Journal of Radiation Industry (방사선산업학회지)

Korean Society of Radiation Industry (한국방사선산업학회)
권호 표지

Characterization of Radiation Fabricated Imidazole Based Hydrogel

이미다졸 기반 수화겔의 방사선 합성 및 특성 평가

  • Gwon, Hui-Jeong (Research Division for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Jeong, Jin-Oh (Research Division for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Jeong, Sung In (Research Division for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Park, Jong-Seok (Research Division for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Lim, Youn-Mook (Research Division for Industry & Environment, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute)
  • 권희정 (한국원자력연구원 첨단방사선연구소 공업환경연구부) ;
  • 정진오 (한국원자력연구원 첨단방사선연구소 공업환경연구부) ;
  • 정성린 (한국원자력연구원 첨단방사선연구소 공업환경연구부) ;
  • 박종석 (한국원자력연구원 첨단방사선연구소 공업환경연구부) ;
  • 임윤묵 (한국원자력연구원 첨단방사선연구소 공업환경연구부)
  • Received : 2018.11.05
  • Accepted : 2018.12.17
  • Published : 2018.12.31

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Abstract

Metronidazole (MD), which is used as an antibiotic, is largely used as an oral and skin application agent, and has inhibiting effect on the production of the fungus causing malodor. However, the maximum drug inclusion concentration is 0.75% of skin ointment in commercially available. In this study, hydrogels containing high concentration of metronidazole were prepared by using radiation crosslinking technique based on biocompatible polymers, and release characteristics and antimicrobial properties were evaluated. This study was preliminary carried out to investigate whether it could be used effectively as antibacterial dressing materials.

Keywords

Acknowledgement

Supported by : 과학기술정보통신부

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