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Understanding animal models on colorectal cancer

대장암 동물 모델에 대한 이해

  • 임도영 (Mayo 병원 소아청소년의학과)
  • Received : 2018.11.06
  • Accepted : 2018.11.21
  • Published : 2018.12.31

Abstract

Colorectal cancer (CRC) is a third leading cause of cancer-related death in cancer patients. Sporadic and inflammation-related colon carcinogenesis are major mechanism of colorectal cancer. In vivo CRC models have been developed and implicated to understand their mechanisms upon a different type of CRC. Moreover, recently animal models have played important roles in chemopreventive and preclinical trials over the years. In this mini-review, the aim is to introduce various animal models of CRC and help the understanding to establish in vivo experimental plans according to the cancer type of CRC.

Keywords

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