Investigative Magnetic Resonance Imaging

Korean Society of Magnetic Resonance in Medicine (대한자기공명의과학회)
권호 표지
DOI QR코드

DOI QR Code

Recurrent Neuro-Sweet Disease Associated with Preceding Upper Respiratory Infection: a Case Study

  • Suh, Hie Bum (Department of Radiology, Pusan National University Hospital, Pusan National University School of Magnetic resonance imaging Medicine and Medical Research Institute) ;
  • Kim, Hak Jin (Department of Radiology, Pusan National University Hospital, Pusan National University School of Magnetic resonance imaging Medicine and Medical Research Institute)
  • Received : 2018.06.04
  • Accepted : 2018.07.10
  • Published : 2018.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

Sweet's syndrome also known as acute neutrophilic dermatosis is a multisystem inflammatory disorder characterized by fever, malaise, leukocytosis, and skin lesions. Sweet's syndrome affects multiple organs though only rarely does it affect the central nervous system (CNS) when it does it is called Neuro-Sweet disease (NSD). We report on a case study of a biopsy-proven NSD in a 50 year old man. Serial magnetic resonance imaging (MRI) showed repeated CNS involvement of Sweet's syndrome after a respiratory tract infection preceded it. On the MRI, T2 hyperintense lesions occurred at multiple sites and disappeared after steroid therapy.

Keywords

References

  1. Sweet RD. An acute febrile neutrophilic dermatosis. Br J Dermatol 1964;76:349-356 https://doi.org/10.1111/j.1365-2133.1964.tb14541.x
  2. Cohen PR, Kurzrock R. Sweet's syndrome revisited: a review of disease concepts. Int J Dermatol 2003;42:761-778 https://doi.org/10.1046/j.1365-4362.2003.01891.x
  3. Hisanaga K, Iwasaki Y, Itoyama Y, Neuro-Sweet Disease Study Group. Neuro-Sweet disease: clinical manifestations and criteria for diagnosis. Neurology 2005;64:1756-1761 https://doi.org/10.1212/01.WNL.0000161848.34159.B5
  4. Cohen PR. Sweet's syndrome--a comprehensive review of an acute febrile neutrophilic dermatosis. Orphanet J Rare Dis 2007;2:34 https://doi.org/10.1186/1750-1172-2-34
  5. Hiari N, Borland C. A 47-year-old man with neuro-Sweet syndrome in association with Crohn's disease: a case report. J Med Case Rep 2009;3:8997 https://doi.org/10.4076/1752-1947-3-8997
  6. Hisanaga K, Hosokawa M, Sato N, Mochizuki H, Itoyama Y, Iwasaki Y. "Neuro-sweet disease": benign recurrent encephalitis with neutrophilic dermatosis. Arch Neurol 1999;56:1010-1013 https://doi.org/10.1001/archneur.56.8.1010
  7. Singh JS, Costello F, Nadeau J, Witt S, Trotter MJ, Goyal M. Case 176: Neuro-sweet syndrome. Radiology 2011;261:989-993 https://doi.org/10.1148/radiol.11092052
  8. Kim YK, Bang D. Sweet’s syndrome associated with bacterial meningitis. Ann Dermatol 1996;8:66-69 https://doi.org/10.5021/ad.1996.8.1.66
  9. Akiba C, Esaki T, Ando M, et al. Possible neuro-Sweet disease mimicking brain tumor in the medulla oblongata-- case report. Neurol Med Chir (Tokyo) 2011;51:140-143 https://doi.org/10.2176/nmc.51.140
  10. Makimoto G, Manabe Y, Yamakawa C, et al. Two cases of possible neuro-Sweet disease with meningoencephalitis as the initial manifestation. Neurol Int 2012;4:e5 https://doi.org/10.4081/ni.2012.e5