Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Simultaneous determination of methoxyflavones in selected Korean thistles

  • Rodriguez, Joyce P. (Department of Integrative Plant Science, Chung-Ang University) ;
  • Quilantang, Norman G. (Department of Integrative Plant Science, Chung-Ang University) ;
  • Lee, Ju Sung (Department of Integrative Plant Science, Chung-Ang University) ;
  • Park, Jun Yeon (Department of Food Science and Biotechnology, Kyonggi University) ;
  • Shim, Jae Suk (Imsil Herbal Medicine Association) ;
  • Kang, Ki Sung (College of Korean Medicine, Gachon University) ;
  • Cho, Eun Ju (Department of Food Science and Nutrition, Pusan National University) ;
  • Geraldino, Paul John L. (Department of Biology, University of San Carlos) ;
  • Lee, Sanghyun (Department of Integrative Plant Science, Chung-Ang University)
  • Received : 2018.06.26
  • Accepted : 2018.07.17
  • Published : 2018.09.29
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Abstract

Simultaneous determination of three methoxyflavones, namely, cirsimarin (1), hispidulin (2), and cirsimaritin (3) in selected Korean thistles was performed via reversed-phase high performance liquid chromatography system. Compound 1 was present in all the thistle species examined, whereas 2 and 3 were only detected in Cirsium japonicum and C. japonicum var. maackii (CJM). The concentration of compounds 1-3 in CJM varied according to the time of harvest. Plants collected in the spring (CJMS) and fall (CJMF) had the highest contents of 3 and 1, respectively. A lower content of 2 was observed in CJMF than in CJMS. This indicates that seasonal variation affects the flavonoid content of CJM. The results of this study show that CJM is an excellent source of compounds 1-3 and it can potentially be cultivated for industrial and pharmaceutical applications involving these compounds.

Keywords

References

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