대한상부위장관⦁헬리코박터학회지 (The Korean journal of helicobacter and upper gastrointestinal research)

  • 제18권4호
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  • Pages.247-257
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  • 2018
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  • 1738-3331(pISSN)
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  • 2671-826X(eISSN)
대한상부위장관ㆍ헬리코박터학회 (Korean College of Helicobacter and upper Gastrointestinal Reseaarch)
권호 표지
DOI QR코드

DOI QR Code

위축성 위염과 장상피화생의 유병률 변화 및 위험인자의 변화: 다기관 연구 비교

Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials

  • 황영재 (분당서울대학교병원 내과) ;
  • 김나영 (분당서울대학교병원 내과) ;
  • 김성은 (고신대학교 의과대학 내과학교실) ;
  • 백광호 (한림대학교 의과대학 내과학교실) ;
  • 이주엽 (계명대학교 의과대학 내과학교실) ;
  • 박경식 (계명대학교 의과대학 내과학교실) ;
  • 주영은 (전남대학교 의과대학 내과학교실) ;
  • 명대성 (전남대학교 의과대학 내과학교실) ;
  • 김현주 (제주대학교 의학전문대학원 가정의학교실) ;
  • 송현주 (제주대학교 의학전문대학원 내과학교실) ;
  • 김흥업 (제주대학교 의학전문대학원 내과학교실) ;
  • 남광우 (단국대학교 의과대학 내과학교실) ;
  • 신정은 (단국대학교 의과대학 내과학교실) ;
  • 김현진 (경상대학교 의과대학 내과학교실, 건강과학연구원) ;
  • 김광하 (부산대학교 의과대학 내과학교실) ;
  • 이종찬 (분당서울대학교병원 내과) ;
  • 임선희 (서울대학교병원 헬스케어시스템 강남센터 내과 및 헬스케어연구소) ;
  • 서검석 (원광대학교 의과대학 내과학교실) ;
  • 최석채 (원광대학교 의과대학 내과학교실)
  • Hwang, Young-Jae (Department of Internal Medicine, Seoul National University Bundang Hospital) ;
  • Kim, Nayoung (Department of Internal Medicine, Seoul National University Bundang Hospital) ;
  • Kim, Sung Eun (Department of Internal Medicine, Kosin University College of Medicine) ;
  • Baik, Gwang Ho (Department of Internal Medicine, College of Medicine, Hallym University) ;
  • Lee, Ju Yup (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Park, Kyung Sik (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Joo, Young-Eun (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Myung, Dae-Seong (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Kim, Hyeon Ju (Department of Family Medicine, Jeju National University School of Medicine) ;
  • Song, Hyun Joo (Department of Internal Medicine, Jeju National University School of Medicine) ;
  • Kim, Heung Up (Department of Internal Medicine, Jeju National University School of Medicine) ;
  • Nam, Kwangwoo (Department of Internal Medicine, Dankook University College of Medicine) ;
  • Shin, Jeong Eun (Department of Internal Medicine, Dankook University College of Medicine) ;
  • Kim, Hyun Jin (Department of Internal Medicine and Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Kim, Gwang Ha (Department of Internal Medicine, Pusan National University School of Medicine) ;
  • Lee, Jongchan (Department of Internal Medicine, Seoul National University Bundang Hospital) ;
  • Lim, Seon Hee (Department of Internal Medicine, Seoul National University Healthcare System Gangnam Center and Healthcare Research Institute) ;
  • Seo, Geom Seog (Department of Internal Medicine, Wonkwang University School of Medicine) ;
  • Choi, Suck Chei (Department of Internal Medicine, Wonkwang University School of Medicine)
  • 투고 : 2018.07.23
  • 심사 : 2018.09.06
  • 발행 : 2018.12.31
⟨ 이전 논문 다음 논문 ⟩

초록

Background/Aims: The aim of this study was to analyze the trend of the prevalences of atrophic gastritis (AG) and intestinal metaplasia (IM) from 2011 to 2016~2017 in Korea. And, the risk factors of AG and IM were compared between 2011 and 2016~2017. Materials and Methods: A total of 4,023 subjects in 2011 and 2,506 subjects in 2016~2017 were enrolled. AG and IM were diagnosed on the basis of endoscopic findings. Multivariate analysis was performed for risk factors of AG and IM. Seventeen factors were analyzed. Results: The seroprevalence of Helicobacter pylori decreased from 2011 (59.8%; 2,407/4,023) to 2016~2017 (51.6%; 1,293/2,506; P<0.001). The prevalence of AG decreased from 2011 to 2016~2017 (P=0.018), but that of IM increased (P<0.001). The risk factors of AG in 2011 were male sex, old age, H. pylori immuoglobulin G (IgG) positivity, family history of gastric cancer (GC), and high-salt diet. For IM in 2011, the risk factors were male sex, old age, H. pylori IgG positivity, and family history of GC. Risk factors of AG in 2016~2017 were old age, H. pylori IgG positivity, and country of residence. For IM in 2016~2017, the risk factors were male sex, old age, family history of GC, high fasting glucose level (${\geq}126mg/dL$), H. pylori IgG positivity, and low income level. Conclusions: The difference in prevalence trends of AG and IM between 2016~2017 and 2011 could be the result of the different risk factors of AG and IM, such as decreased prevalence of H. pylori infection.

키워드

과제정보

연구 과제 주관 기관 : National Research Foundation of Korea (NRF)

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