Journal of Bone Metabolism (대한골대사학회지)

The Korean Society for Bone and Mineral Research (대한골대사학회)
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Which Index for Muscle Mass Represents an Aging Process?

  • Kim, Hyung-Kook (Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine) ;
  • Lee, You Jin (Department of Internal Medicine, Center for Thyroid Cancer, National Cancer Center) ;
  • Lee, Young-Kyun (Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine) ;
  • Kim, Hongji (Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine) ;
  • Koo, Kyung-Hoi (Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine)
  • Received : 2018.08.16
  • Accepted : 2018.09.28
  • Published : 2018.11.30
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Abstract

Background: Although studies and interest in sarcopenia have increased, it is still a matter of debate which muscle mass index better represents the aging process. We compared 3 indices for muscle mass (appendicular skeletal muscle mass [ASM]/weight, $ASM/height^2$, and the body mass index [BMI]-adjusted muscle mass index [ASM/BMI]) to determine which better reflected the aging process in terms of the decline in bone mineral density (BMD), visual acuity (VA), hearing power, renal function, pulmonary function, and handgrip strength. Methods: We performed a retrospective cross-sectional study using the Korea National Health and Nutrition Examination Survey in the Korean population. Between 2008 and 2011, a total of 14,415 men and 17,971 women aged 10 years or older participated in the study. We plotted the changes in the 3 indices of muscle mass and compared these with changes in BMD, VA, hearing power, renal function, pulmonary function, and handgrip strength according to each age group. Results: The ASM/BMI showed similar changes in terms of surrogate markers of the aging process, while the ASM/weight and $ASM/height^2$ showed no correlation. Conclusions: Among muscle indices for sarcopenia, only the ASM/BMI represented the aging process.

Keywords

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