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Chemotherapy Induced Peripheral Neuropathy, Sleep and Quality of Life among Patients with Gastric Cancer Receiving Chemotherapy

항암화학요법을 받는 위암 환자의 말초신경병증, 수면 및 삶의 질에 대한 연구

  • Kim, Hyemi (National Cancer Center.Graduate School of Clinical Health Sciences, Ewha Womans University) ;
  • Park, Hyojung (College of Nursing.Ewha Research Institute of Nursing Science, Ewha Womans University)
  • 김혜미 (국립암센터 간호사.이화여자대학교 임상보건융합대학원) ;
  • 박효정 (이화여자대학교 간호대학.이화간호과학연구소)
  • Received : 2018.04.09
  • Accepted : 2018.07.13
  • Published : 2018.08.31

Abstract

Purpose: Purpose of this study was to investigate relationships and influence of peripheral neuropathy, sleep, and quality of life in patients with gastric cancer who are receiving chemotherapy. Methods: Participants were 131 patients with gastric cancer being treated at a chemotherapy outpatient clinic and receiving chemotherapy. Data were analyzed using descriptive statistics, t-test, ANOVA, and multiple regression analysis with the SPSS program. Results: Mean score for peripheral neuropathy was 24.66, for sleep, 6.71 and for quality of life, 67.69. Peripheral neuropathy had a significant positive correlation with sleep (r=.26, p=.003) and sleep had a significant negative correlation with quality of life (r=-.50, p<.001). The regression model explaining quality of patients'lives was significant (F=11.91, p<.001), peripheral neuropathy, sleep, and pain due to anticancer drugs and number ofneurotoxic anticancer drugs explained 25.1% of the variance in quality of life and sleep was the most important factor. Conclusion: To improve the quality of life for these patients, individualized nursing interventions for pain should be provided according to number of anticancer drugs in the chemotherapy. Also there is a need to identify ways to assess peripheral neuropathy and sleep disorders that are appropriate in the treatment and reduce side effects during treatment.

Keywords

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