Journal of Korean Medical Science

Korean Acad Medical Sciences (대한의학회)
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National Registry Data from Korean Neonatal Network: Two-Year Outcomes of Korean Very Low Birth Weight Infants Born in 2013-2014

  • Youn, YoungAh (Department of Pediatrics, Seoul St. Mary's Hospital, The Catholic University of Korea) ;
  • Lee, Soon Min (Department of Pediatrics, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Hwang, Jong-Hee (Department of Pediatrics, Inje University College of Medicine, Ilsan Paik Hospital) ;
  • Cho, Su Jin (Department of Pediatrics, Ewha Womans University, College of Medicine) ;
  • Kim, Ee-Kyung (Departmemt of Pediatrics, Seoul National University Children's Hospital) ;
  • Kim, Ellen Ai-Rhan (Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine)
  • Received : 2018.06.11
  • Accepted : 2018.08.16
  • Published : 2018.11.29
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Abstract

Background: The aim of this study was to observe long-term outcomes of very low birth weight infants (VLBWIs) born between 2013 and 2014 in Korea, especially focusing on neurodevelopmental outcomes. Methods: The data were collected from Korean Neonatal Network (KNN) registry from 43 and 54 participating units in 2013 and 2014, respectively. A standardized electronic case report form containing 30 items related to long-term follow up was used after data validation. Results: Of 2,660 VLBWI, the mean gestational age and birth weight were $29^{1/7}{\pm}2^{6/7}$ weeks and $1,093{\pm}268g$ in 2013 and $29^{2/7}{\pm}2^{6/7}$ weeks and $1,125{\pm}261g$ in 2014, respectively. The post-discharge mortality rate was 1.2%-1.5%. Weight < 50th percentile was 46.5% in 2013 and 66.1% in 2014. The overall prevalence of cerebral palsy among the follow up infants was 6.2% in 2013 and 6.6% in 2014. The Bayley Scales of Infant Developmental Outcomes version II showed 14%-25% of infants had developmental delay and 3%-8% of infants in Bayley version III. For the Korean developmental screening test for infants and children, the area "Further evaluation needed" was 5%-12%. Blindness in both eyes was reported to be 0.2%-0.3%. For hearing impairment, 0.8%-1.9% showed bilateral hearing loss. Almost 50% were readmitted to hospital with respiratory illness as a leading cause. Conclusion: The overall prevalence of long-term outcomes was not largely different among the VLBWI born between 2013 and 2014. This study is the first large national data study of long-term outcomes.

Keywords

Acknowledgement

Supported by : Korea Centers for Disease Control and Prevention

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