DOI QR코드

DOI QR Code

Association between Blood Mercury and Drinking Soju and Beer in Korea

소주 및 맥주 음주와 혈중 수은과의 관계에 관한 연구

  • Cho, Jun Ho (Department of Public Health Administration, Hanyang Women's University)
  • 조준호 (한양여자대학교 보건행정과)
  • Received : 2018.07.16
  • Accepted : 2018.08.09
  • Published : 2018.08.28

Abstract

Objectives: The purpose of this study was to investigate the relationship between frequency of alcohol drinking and blood mercury concentration in Korea. Methods: This was a cross-sectional study that used data from the Korean National Health and Nutrition Examination Survey. Among them, 3,174 persons were selected for the final study. Results: The concentration of mercury in the blood increased as the frequency of drinking soju or beer increased. Similarly, in the multiple-linear regression analysis model, the frequency of soju drinking was identified as an independent variable showing a statistically significant positive linearity (p<0.001). After controlling for confounding factors, comparing those drinking 'more than twice a week' with those who almost do not drink alcohol, the adjusted ORs for exposure to high concentrations of mercury were 3.24 (95% CI, 2.10-4.99) for drinking soju and 2.07 (95% CI, 1.33-3.22) for drinking beer. The interaction effect between 'soju drinking' and 'spicy pollack and seafood stew' was not statistically significant (p=0.098) for evaluating the interaction effect between the two variables. Conclusions: The concentration of mercury in the blood increased as the frequency of drinking of soju or beer increased. The higher the frequency of alcohol drinking, the more likely is the blood mercury to be included in the high-concentration group. The results of this study can be used as important scientific evidence for the field of environmental health related to alcohol drinking and blood heavy metal exposure in Korea.

Keywords

References

  1. Biomonitoring: Mercury. America's Children and the Environment Third Edition, Updated October 2015. https://www.epa.gov/sites/production/files/2015-10/documents/ace3_mercury.pdf
  2. Toxicological Effects of Methylmercury. Chaper 5. HEALTH EFFECTS OF METHYLMERCURY https://www.ncbi.nlm.nih.gov/books/NBK225765/
  3. Chung SH, Myong JP. Are higher blood mercury levels associated with dry eye symptoms in adult Koreans? A population-based cross-sectional study. BMJ Open. 2016 Apr 27;6(4):e010985. doi: 10.1136/bmjopen-2015-010985.
  4. Kim DS, Ahn SC, Chung HU, Kwon YM, CHOI KH. A Study on Schoolchildren's Mercury Exposure and Related Health Effects in High Mercury Exposure Areas in Korea. J Environ Health Sci. 2015; 41(4): 268-276.
  5. Ministry of Environment. Press Release. Results of Environmental Hazardous Substance Concentration in Children and Adolescents. 2014. 01. 21. http://www.me.go.kr/home/web/board/read.do?menuId=286&boardMasterId=1&boardCategoryId=39&boardId=338815
  6. Kim DS, Chung HU, Kwon YM, Yu HY. Yoon YS, Ahn SC, Jeon HL Hong YS, Lee EH, Oh HJ. 2011. National Institute of Environmental Research. Research on exposure and health effect of mercury in Young-Nam area (II).
  7. Raimann X, Rodriguez OL, Chavez P, Torrejon C. Mercury in fish and its importance in health. Rev Med Chil. 2014 Sep;142(9):1174-80. doi: 10.4067/S0034-98872014000900012.
  8. US EPA. Mercury Emissions. Report on the Environment. https://cfpub.epa.gov/roe/indicator.cfm?i=14
  9. Oh JS, Lee SH. Pb, Hg and Cd Concentration of Blood and Exposure-Related Factors. Journal of the Korea Academia-Industrial cooperation Society 2015; 16(3): 2089-2099. https://doi.org/10.5762/KAIS.2015.16.3.2089
  10. Kim HR, Youn JW, Kim YY. Effects of smoking on concentration of heavy metals in blood and clinical characteristics. PUBLIC HEALTH WEEKLY REPORT 2017; 10(29): 748-753.
  11. Kang DK, Lee KY. The Relationships Between Blood Mercury Concentration and Body Composition Measures Using 2010 Korean National Health and Nutrition Examination Survey. Korean J Obes Vol. 22 No. 4: 237-242. December 2013. https://doi.org/10.7570/kjo.2013.22.4.237
  12. Lim SS, Vos T, Flaxman AD et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380: 2224-60. https://doi.org/10.1016/S0140-6736(12)61766-8
  13. Iwegbue CM, Ojelum AL, Bassey FI. A survey of metal profiles in some traditional alcoholic beverages in Nigeria. Food Sci Nutr. 2014 Nov; 2(6): 724-33. doi:10.1002/fsn3.163. Epub 2014 Sep 9.
  14. Park S, Lee BK. Strong positive associations between seafood, vegetables, and alcohol with blood mercury and urinary arsenic levels in the Korean adult population. Arch Environ Contam Toxicol. 2013 Jan; 64(1): 160-70. doi:10.1007/s00244-012-9808-x. Epub 2012 Sep 21.
  15. Cho JH. The study on effect factors related to blood mercury concentrations for the purpose of preparing the methods to reduce the mercury exposure in Korea. Doosan Yonkang Foundation. Collection of Dissertations for Environment and Safety, 2016, 23, 539-569.
  16. Centers for Disease Control and Prevention (CDC). Blood mercury levels in young children and child-bearing-aged women-United States, 1999-2002. MMWR Morb Mortal Wkly Rep. 2004 Nov 5; 53(43): 1018-20.
  17. Frias S, Diaz C, Conde JE, Perez Trujillo JP. Selenium and mercury concentrations in sweet and dry bottled wines from the Canary Islands, Spain. Food Addit Contam. 2003; 20: 237-240. https://doi.org/10.1080/0265203021000050626
  18. Ibanez JG, Carreon-Alvarez A, Barcena-Soto M, Casillas N. Metals in alcoholic beverages: A review of sources, effects, concentrations, removal, speciation, and analysis. Journal of Food Composition and Analysis 21 (2008) 672-683. https://doi.org/10.1016/j.jfca.2008.06.005
  19. No KM, Kang KM, Baek SL, Choi H, Park SK, Kim DS. Monitoring of Heavy Metal Content in Alcoholic Beverages. Journal of Food Hygiene and Safety 2010; 25(1): 24-29.
  20. KIM DS, Kwon YM, Chung HU, CHOI KH. Mercury Exposure Factors among Residents in the Highly Mercury Exposed Area, Seoksan-ri, Korea. J Environ Health Sci. 2015; 41(5): 349-357.
  21. Ministry of Government Legislation. Liquor tax law. 2018. 7.27. http://www.law.go.kr/lsSc.do?tabMenuId=tab18&p1=&subMenu=1&nwYn=1section=&tabNo=&query=%EC%A3%BC%EC%84%B8%EB%B2%95#undefined
  22. Min SR. Quality Characteristics of Distilled Soju with Various Aspergillus Species. Department of Food Science and Technology. Graduate School Sunchon National University. 2013.
  23. Zhang H, Wang D, Zhang J, Shang X, Zhao Y, Wu Y. Total mercury in milled rice and brown rice from China and health risk evaluation. Food Addit Contam Part B Surveill. 2014; 7(2): 141-6. doi:10.1080/19393210.2013.860485. Epub 2014 Jan 10.
  24. Ministry of Government Legislation. Liquor Tax Enforcement Decree. 2018.7.27. http://www.law.go.kr/lsSc.do?tabMenuId=tab18&p1=&subMenu=1&nwYn=1§ion=&tabNo=&query=%EC%A3%BC%EC%84%B8%EB%B2%95#undefined
  25. Dufault R, LeBlanc B, Schnoll R, Cornett C, Schweitzer L, Wallinga D, Hightower J, Patrick L, Lukiw WJ. Mercury from chlor-alkali plants: measured concentrations in food product sugar. Environ Health. 2009 Jan 26; 8:2. doi:10.1186/1476-069X-8-2.
  26. Ogimoto M, Uematsu Y, Suzuki K, Kabashima J, Nakazato M. Survey of toxic heavy metals and arsenic in existing food additives (natural colors). Shokuhin Eiseigaku Zasshi. 2009 Oct; 50(5): 256-60. https://doi.org/10.3358/shokueishi.50.256
  27. Rumbeiha WK, Gentry PA, Bhatnagar MK. The effects of administering methylmercury in combination with ethanol in the rat. Vet Hum Toxicol 1992; 34, 21-25.
  28. Ministry of Food and Drug Safety. Press Release. "If you drink or smoke, heavy metals accumulate in your body." 2017.06.13.