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Evaluation of Total and Soluble Fluoride Concentrations in Ten Toothpastes for Children

어린이 치약의 총 불소 함량과 용해성 불소 함량의 평가

  • Park, Nakyoung (Department of Pediatric Dentistry, College of Dentistry, Wonkwang University) ;
  • Song, Jihyun (Department of Pediatric Dentistry, College of Dentistry, Wonkwang University)
  • 박나경 (원광대학교 치과대학 소아치과학교실) ;
  • 송지현 (원광대학교 치과대학 소아치과학교실)
  • Received : 2017.10.30
  • Accepted : 2017.11.21
  • Published : 2018.05.31

Abstract

In this study, total fluoride (TF) in commercial toothpastes for children in Korea was evaluated and compared with the fluoride concentration declared by the manufacturer (Declared F). Additionally, total soluble fluoride (TSF) was evaluated and compared with TF. Ten toothpastes were coded with letters to allow blind analysis. For evaluation of TF, each toothpaste was homogenized in deionized water. For evaluation of TSF, each toothpaste was centrifuged and then, the supernatant of the sample was evaluated. Fluoride concentrations were assessed using a fluoride electrode coupled to an ion analyzer. Only one toothpaste showed lower TF concentration than Declared F. In all toothpastes, TSF was similar to the TF.

본 연구에서는 한국에서 판매되는 어린이 치약의 총 불소 함량을 측정하여 이를 제조사에서 표기한 불소 함량과 비교하였으며, 총 용해성 불소 함량을 측정하여 총 불소 함량과 비교하였다. 치약들은 맹검 시험을 위해 알파벳을 이용하여 암호화 되었다(A-J). 총 불소 함량의 측정을 위해 각 치약들은 증류수에 희석되었다. 총 용해성 불소 함량은 원심분리 후 상층액을 채득하여 측정되었다. 각 치약들의 불소함량은 불소이온전극이 연결된 이온 분석기를 이용하여 측정되었다. 실험에 사용된 10개의 제품 중, 9개는 제조사에서 표기한 불소 함량과 유사한 총 불소 함량을 보였다. 한 개의 제품은 제조사에서 표기한 불소 함량보다 적은 양의 총 불소 함량을 보였다. 모든 제품들은 총 불소 함량과 비슷한 정도의 총 용해성 불소 함량을 보였다.

Keywords

References

  1. McDonald RE, Avery DR : Dentistry for the child and adolescent, 9th ed. Mosby, 194-200, 2011.
  2. Marthaler TM, Mullane DMO, Vrbic V : The prevalence of dental caries in Europe 1990-1995. Caries Res, 30:237-255, 1996. https://doi.org/10.1159/000262332
  3. Wright JT, Hanson N, Zentz RR, et al. : Fluoride toothpaste efficacy and safety in children younger than 6 years. J Am Dent Assoc, 145:182-189, 2014. https://doi.org/10.14219/jada.2013.37
  4. Santos APP, Nadanovsky P, Oliveira BH : A systematic review and meta-analysis of the effects of fluoride toothpastes on the prevention of dental caries in the primary dentition of preschool children. Community Dent Oral Epidemiol, 41:1-12, 2013. https://doi.org/10.1111/j.1600-0528.2012.00708.x
  5. Twetman S, Axelsson S, Soder B, et al. : Caries-preventive effect of fluoride toothpaste: a systematic review. Acta Odontol Scand, 61:347-355, 2003. https://doi.org/10.1080/00016350310007590
  6. Ministry of Food and Drug Safety. Available from URL: http://www.mfds.go.kr/index.do?x=0&searchkey=title:contents&mid=686&searchword=%C0%C7%BE%E0%BF%DC%C7%B0&y=0&division=&pageNo=1&seq=11736&sitecode=2017-03-16&cmd=v (Accessed on May 1, 2017).
  7. Tenuta LMA, Zamataro CB, Cury JA, et al. : Mechanism of fluoride dentifrice effect on enamel demineralization. Caries Res, 43:278-285, 2009. https://doi.org/10.1159/000217860
  8. Cury JA, Tenuta LMA : How to maintain a cariostatic fluoride concentration in the oral environment. Adv Dent Res, 20:13-16, 2008. https://doi.org/10.1177/154407370802000104
  9. Giacaman RA, Carrera CA, Cury JA, et al. : Fluoride content in toothpastes commercialized for children in Chile and discussion on professional recommendations of use. Int J Paediatr Dent, 23:77-83, 2013. https://doi.org/10.1111/j.1365-263X.2012.01226.x
  10. Jordan RA, Markovic L, Gaengler P, Zimmer S : Total and free fluoride concentrations of African Dentifrices marketed in West Africa. Oral Health Prev Dent, 9:53-58, 2011.
  11. Kikwilu EN, Frencken JE, Mulder J : Utilization of toothpaste and fluoride content in toothpaste manufactured in Tanzania. Acta Odontol Scand, 66:293-299, 2008. https://doi.org/10.1080/00016350802297748
  12. Park RS, Baek EM, Bae TS, et al. : Fluoride recharge/release after toothbrushing with fluoride dentifrice. J Korea Res Soc Dent Mater, 34:75-82, 2007.
  13. Twetman S, Axelsson S, Soder B, et al. : Caries-preventive effect of fluoride toothpaste: a systematic review. Acta Odontol Scand, 61:347-355, 2003. https://doi.org/10.1080/00016350310007590
  14. Ministry of Health and Welfare. Available from URL: http://www.mfds.go.kr/index.do?mid=687&pageNo=1&seq=11941&sitecode=2017-05-19&cmd=v (Accessed on May 1, 2017).
  15. Twetman S : Caries prevention with fluoride toothpaste in children: an update. Eur Arch Paediatr Dent, 10:162-167, 2009. https://doi.org/10.1007/BF03262678
  16. Ko HY, Kang SM, Kwon HK, Kim BI : Evaluation of fluoride bioavailability in toothpastes. J Korean Acad Dent Health, 39:81-87, 2015. https://doi.org/10.11149/jkaoh.2015.39.2.81
  17. Conde NCO, Rebelo MAB, Cury JA : Evaluation of the fluoride stability of dentifrices sold in Manaus, AM, Brazil. Pesqui Odontol Bras, 17:247-253, 2003. https://doi.org/10.1590/S1517-74912003000300009
  18. Hong SJ, Park YN, Lee KH, et al. : Fluoride concentration of commercial dentifrices for children in Korea. J Korean Acad Dent Health, 32:143-151, 2008.
  19. Ko SK, Lee MS, Chae YZ, et al. : Determination of fluoride in dentifrice marketed in Korea using a fluoride-selective electrode. Report of S.I.H.E., 48:74-82, 2012.
  20. Kwon HK, Lee YH, Kim KS, Cho BK : Salivary fluoride concentration after toothbrushing with NaF- and SMFP-containing toothpastes. J Korean Acad Dent Health, 20:555-567, 1996.
  21. Kim JH, Jeong SS, Choi CH, Hong SJ : Fluoride concentration of commercial dentifrices and effect of fluoride containing dentifrices on artificial enamel caries. J Korean Acad Dent Health, 30:56-66, 2006.
  22. American dental association council on scientific affairs : Fluoride toothpaste use for young children. J Am Dent Assoc , 145:190-191, 2014. https://doi.org/10.14219/jada.2013.47
  23. American academy of pediatric dentistry council on clinical affairs : Guideline on fluoride therapy. Pediatr Dent, 36:171-174, 2014.
  24. Canadian Dental Association : Dental care for children by Canadian Dental Association. Available from URL: http://www.cda-adc.ca/en/oral_health/cfyt/dental_care_children/cleaning.asp (Accessed on May 1, 2017).
  25. Korean Academy of Pediatric Dentistry : Textbook of Pediatric Dentistry, 5th ed. Yenang, 299-311, 2014.
  26. Korean Academy of Pediatric Dentistry : Guideline of Academy of Pediatric Dentistry. Available from URL: http://www.kapd.org/publicbbs_kr/?mode=v&refnum=24853 (Accessed on October 20, 2017).