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개회충증 환자에서 발생한 급성 호산구성 단관절염 1예

Acute Eosinophilic Monoarthritis in a Patient with Toxocariasis

  • 허재형 (분당서울대학교병원 내과) ;
  • 하유정 (분당서울대학교병원 내과) ;
  • 정상완 (분당서울대학교병원 내과) ;
  • 강은하 (분당서울대학교병원 내과) ;
  • 송영욱 (서울대학교 의과대학 내과학교실) ;
  • 이윤종 (분당서울대학교병원 내과)
  • Hur, Jaehyung (Department of Internal Medicine, Seoul National University Bundang Hospital) ;
  • Ha, You Jung (Department of Internal Medicine, Seoul National University Bundang Hospital) ;
  • Chung, Sang Wan (Department of Internal Medicine, Seoul National University Bundang Hospital) ;
  • Kang, Eun Ha (Department of Internal Medicine, Seoul National University Bundang Hospital) ;
  • Song, Yeong Wook (Department of Internal Medicine, Seoul National University College of Medicine) ;
  • Lee, Yun Jong (Department of Internal Medicine, Seoul National University Bundang Hospital)
  • 투고 : 2016.12.15
  • 심사 : 2017.10.19
  • 발행 : 2018.08.01

초록

저자들은 혈액 및 활막액 호산구증가증이 동반된 급성 무릎 단관절염 환자에서 개회충증 감염을 진단하고 글루코코 르티코이드 관절강내 주사와 함께 알벤다졸 투약을 통하여 치료한 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Eosinophilic synovial effusion is rarely observed in patients with inflammatory nature of synovial fluid, and the differential diagnosis includes parasitic arthritis. Toxocariasis is the one of the most common forms of helminthiasis worldwide and has been reported as a common cause of peripheral blood eosinophilia in Korea. However, joint involvement has been rarely reported in adults with toxocariasis in the English-language literature. Here, we report the first Korean case of a female presenting with acute monoarthritis with an increased number of eosinophils in the peripheral blood and synovial fluid, who was finally diagnosed with toxocariasis.

키워드

참고문헌

  1. Dougados M. Synovial fluid cell analysis. Baillieres Clin Rheumatol 1996;10:519-534. https://doi.org/10.1016/S0950-3579(96)80047-1
  2. Seo M. Clinical update on parasitic diseases. Korean J Med 2013;85:469-480. https://doi.org/10.3904/kjm.2013.85.5.469
  3. Ahn SJ, Woo SJ, Jin Y, et al. Clinical features and course of ocular toxocariasis in adults. PLoS Negl Trop Dis 2014;8:e2938. https://doi.org/10.1371/journal.pntd.0002938
  4. Kim YH, Huh S, Chung YB. Seroprevalence of toxocariasis among healthy people with eosinophilia. Korean J Parasitol 2008;46:29-32. https://doi.org/10.3347/kjp.2008.46.1.29
  5. Lee JY, Yang MH, Hwang JH, et al. The prevalence of toxocariasis and diagnostic value of serologic tests in asymptomatic Korean adults. Allergy Asthma Immunol Res 2015;7:467-475. https://doi.org/10.4168/aair.2015.7.5.467
  6. Vazquez-Trinanes C, Sopena B, Gonzalez-Gonzalez L, et al. Synovial fluid eosinophilia: a case series with a long follow-up and literature review. Rheumatology (Oxford) 2013;52:346-351. https://doi.org/10.1093/rheumatology/kes236
  7. Tauro B. Eosinophilic synovitis. A new entity? J Bone Joint Surg Br 1995;77:654-656.
  8. Mazur-Melewska K, Mania A, Figlerowicz M, Kemnitz P, Sluzewski W, Michalak M. The influence of age on a clinical presentation of Toxocara spp. infection in children. Ann Agric Environ Med 2012;19:233-236.
  9. Williams D, Roy S. Arthritis and arthralgia associated with toxocaral infestation. Br Med J (Clin Res Ed) 1981;283:192.
  10. Rayes AA, Lambertucci JR. Human toxocariasis as a possible cause of eosinophilic arthritis. Rheumatology (Oxford) 2001;40:109-110.