References
- Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol 2000; 47:707-17. https://doi.org/10.1002/1531-8249(200006)47:6<707::AID-ANA3>3.0.CO;2-Q
- Geurts JJ, Barkhof F. Grey matter pathology in multiple sclerosis. Lancet Neurol 2008;7:841-51. https://doi.org/10.1016/S1474-4422(08)70191-1
- Norkute A, Hieble A, Braun A, Johann S, Clarner T, Baumgartner W, Beyer C, Kipp M. Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus. J Neurosci Res 2009;87:1343-55. https://doi.org/10.1002/jnr.21946
- Praet J, Guglielmetti C, Berneman Z, Van der Linden A, Ponsaerts P. Cellular and molecular neuropathology of the cuprizone mouse model: clinical relevance for multiple sclerosis. Neurosci Biobehav Rev 2014;47:485-505. https://doi.org/10.1016/j.neubiorev.2014.10.004
- Manto M. Abnormal copper homeostasis: mechanisms and roles in neurodegeneration. Toxics 2014;2:327-45. https://doi.org/10.3390/toxics2020327
- Skripuletz T, Bussmann JH, Gudi V, Koutsoudaki PN, Pul R, Moharregh-Khiabani D, Lindner M, Stangel M. Cerebellar cortical demyelination in the murine cuprizone model. Brain Pathol 2010;20:301-12. https://doi.org/10.1111/j.1750-3639.2009.00271.x
- Skripuletz T, Lindner M, Kotsiari A, Garde N, Fokuhl J, Linsmeier F, Trebst C, Stangel M. Cortical demyelination is prominent in the murine cuprizone model and is strain-dependent. Am J Pathol 2008;172:1053-61. https://doi.org/10.2353/ajpath.2008.070850
- Draheim T, Liessem A, Scheld M, Wilms F, Weissflog M, Denecke B, Kensler TW, Zendedel A, Beyer C, Kipp M, Wruck CJ, Fragoulis A, Clarner T. Activation of the astrocytic Nrf2/ARE system ameliorates the formation of demyelinating lesions in a multiple sclerosis animal model. Glia 2016;64:2219-30. https://doi.org/10.1002/glia.23058
- Suneetha A, Raja Rajeswari K. Role of dimethyl fumarate in oxidative stress of multiple sclerosis: a review. J Chromatogr B Analyt Technol Biomed Life Sci 2016;1019:15-20. https://doi.org/10.1016/j.jchromb.2016.02.010
- Sajjadian M, Kashani IR, Pasbakhsh P, Hassani M, Omidi A, Takzare N, Clarner T, Beyer C, Zendedel A. Protective effects of cannabidiol on cuprizone-induced demyelination in C57BL/6 mice. J Contemp Med Sci 2017;3:278-83. https://doi.org/10.22317/jcms.09201707
- Carvalho AN, Lim JL, Nijland PG, Witte ME, Van Horssen J. Glutathione in multiple sclerosis: more than just an antioxidant? Mult Scler 2014;20:1425-31. https://doi.org/10.1177/1352458514533400
- World Health Organization. Traditional medicine strategy 2002-2005. Geneva: World Health Organization; 2002.
- Eilert U, Wolters B, Nahrstedt A. The antibiotic principle of seeds of Moringa oleifera and Moringa stenopetala. Planta Med 1981;42:55-61. https://doi.org/10.1055/s-2007-971546
- Ezeamuzie IC, Ambakederemo AW, Shode FO, Ekwebelem SC. Antiinflammatory effects of Moringa oleifera root extract. Int J Pharmacogn 1996;34:207-12. https://doi.org/10.1076/phbi.34.3.207.13211
- Gbadamosi IT, Omotoso GO, Olajide OJ, Dada-Habeeb SO, Arogundade TT, Lambe E, Obasi KK. Moringa protects against nicotine-induced morphological and oxidative damage in the frontal cortex of Wistar rats. Anatomy 2016;10:170-6. https://doi.org/10.2399/ana.16.020
- Sreelatha S, Jeyachitra A, Padma PR. Antiproliferation and induction of apoptosis by Moringa oleifera leaf extract on human cancer cells. Food Chem Toxicol 2011;49:1270-5. https://doi.org/10.1016/j.fct.2011.03.006
- Ferreira RS, Napoleao TH, Santos AF, Sa RA, Carneiro-da-Cunha MG, Morais MM, Silva-Lucca RA, Oliva ML, Coelho LC, Paiva PM. Coagulant and antibacterial activities of the watersoluble seed lectin from Moringa oleifera. Lett Appl Microbiol 2011;53:186-92. https://doi.org/10.1111/j.1472-765X.2011.03089.x
- Libro R, Giacoppo S, Soundara Rajan T, Bramanti P, Mazzon E. Natural phytochemicals in the treatment and prevention of dementia: an overview. Molecules 2016;21:518. https://doi.org/10.3390/molecules21040518
- Kasolo JN, Bimenya GS, Ojok L, Ochieng J, Ogwal-okeng JW. Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities. J Med Plants Res 2010;4:753-7.
- Pari L, KaramacM, Kosinska A, Rybarczyk A, Amarowicz R. Antioxidant activity of the crude extracts of drumstick tree (Moringa oleifera Lam.) and sweet broomweed (Scoparia dulcis L.) leaves. Pol J Food Nutr Sci 2007;57:203-8.
- Pace-Asciak CR, Hahn S, Diamandis EP, Soleas G, Goldberg DM. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19. https://doi.org/10.1016/0009-8981(95)06045-1
- Kawada N, Seki S, Inoue M, Kuroki T. Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells. Hepatology 1998;27:1265-74. https://doi.org/10.1002/hep.510270512
- Romanova D, Vachalkova A, Cipak L, Ovesna Z, Rauko P. Study of antioxidant effect of apigenin, luteolin and quercetin by DNA protective method. Neoplasma 2001;48:104-7.
- El-Hawary SS, El-Sofany RH, Abdel-Monem AR, Ashour RS, Sleem AA. Polyphenolics content and biological activity of Plectranthus amboinicus (Lour.) spreng growing in Egypt (Lamiaceae). Pharmacogn J 2012;2:45-54.
- Ganguly R, Hazra R, Ray K, Guha D. Effect of Moringa oleifera in experimental model of Alzheimer's disease: role of antioxidants. Ann Neurosci 2005;12:33-6. https://doi.org/10.5214/ans.0972.7531.2005.120301
- Lassmann H. What drives disease in multiple sclerosis: inflammation or neurodegeneration? Clin Exp Neuroimmunol 2010;1: 2-11. https://doi.org/10.1111/j.1759-1961.2009.00003.x
- Lassmann H. Pathology and disease mechanisms in different stages of multiple sclerosis. J Neurol Sci 2013;333:1-4. https://doi.org/10.1016/j.jns.2013.05.010
- Keynes RG, Garthwaite J. Nitric oxide and its role in ischaemic brain injury. Curr Mol Med 2004;4:179-91. https://doi.org/10.2174/1566524043479176
- Duda JE, Giasson BI, Chen Q, Gur TL, Hurtig HI, Stern MB, Gollomp SM, Ischiropoulos H, Lee VM, Trojanowski JQ. Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies. Am J Pathol 2000;157:1439-45. https://doi.org/10.1016/S0002-9440(10)64781-5
- Acs P, Kipp M, Norkute A, Johann S, Clarner T, Braun A, Berente Z, Komoly S, Beyer C. 17beta-estradiol and progesterone prevent cuprizone provoked demyelination of corpus callosum in male mice. Glia 2009;57:807-14. https://doi.org/10.1002/glia.20806
- Kashani IR, Rajabi Z, Akbari M, Hassanzadeh G, Mohseni A, Eramsadati MK, Rafiee K, Beyer C, Kipp M, Zendedel A. Protective effects of melatonin against mitochondrial injury in a mouse model of multiple sclerosis. Exp Brain Res 2014;232:2835-46. https://doi.org/10.1007/s00221-014-3946-5
- Abe H, Saito F, Tanaka T, Mizukami S, Hasegawa-Baba Y, Imatanaka N, Akahori Y, Yoshida T, Shibutani M. Developmental cuprizone exposure impairs oligodendrocyte lineages differentially in cortical and white matter tissues and suppresses glutamatergic neurogenesis signals and synaptic plasticity in the hippocampal dentate gyrus of rats. Toxicol Appl Pharmacol 2016;290:10-20. https://doi.org/10.1016/j.taap.2015.11.006
- Nathoo N, Yong VW, Dunn JF. Understanding disease processes in multiple sclerosis through magnetic resonance imaging studies in animal models. Neuroimage Clin 2014;4:743-56. https://doi.org/10.1016/j.nicl.2014.04.011
- Debanne D, Campanac E, Bialowas A, Carlier E, Alcaraz G. Axon physiology. Physiol Rev 2011;91:555-602. https://doi.org/10.1152/physrev.00048.2009
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