Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
권호 표지
DOI QR코드

DOI QR Code

A case of nasopharyngeal mucoepidermoid carcinoma in a 5 year-old female patient

소아 비인강에서 발생한 점액표피양암종 1례

  • Yoon, Soyeon (Department of Otorhinolaryngology - Head & Neck Surgery, International St. Mary's Hospital, Catholic Kwandong University) ;
  • Kim, Mijoo (Department of Otorhinolaryngology - Head & Neck Surgery, International St. Mary's Hospital, Catholic Kwandong University) ;
  • Kim, Minbum (Department of Otorhinolaryngology - Head & Neck Surgery, International St. Mary's Hospital, Catholic Kwandong University) ;
  • Hong, Hyunjun (Department of Otorhinolaryngology - Head & Neck Surgery, International St. Mary's Hospital, Catholic Kwandong University) ;
  • Song, Keejae (Department of Otorhinolaryngology - Head & Neck Surgery, International St. Mary's Hospital, Catholic Kwandong University)
  • 윤소연 (가톨릭관동대학교 국제성모병원 이비인후-두경부외과) ;
  • 김미주 (가톨릭관동대학교 국제성모병원 이비인후-두경부외과) ;
  • 김민범 (가톨릭관동대학교 국제성모병원 이비인후-두경부외과) ;
  • 홍현준 (가톨릭관동대학교 국제성모병원 이비인후-두경부외과) ;
  • 송기재 (가톨릭관동대학교 국제성모병원 이비인후-두경부외과)
  • Received : 2018.11.02
  • Accepted : 2018.11.07
  • Published : 2018.11.30
Download PDF
⟨ Previous Next ⟩

Abstract

Malignant salivary gland tumors only represent 0.08% of all childhood tumors. Especially, nasopharyngeal mucoepidermoid carcinoma(MEC) in pediatric age is an extremely rare malignancy. We hereby report a case of nasopharyngeal MEC in 5 year-old female patient. The patient underwent the complete removal of the tumor by endonasal endoscopic approach. Adjuvant postoperative radiotherapy was not considered. After 3.5 years of follow-up, there are no sign of recurrence and metastasis. Minor salivary gland tumor must be considered as a differential diagnosis of angiofibroma in nasopharynx in pediatric age. To our knowledge, the case we describe is the third case of nasopharyngeal MEC in pediatric age reported in literature.

Keywords

References

  1. Kang SH, Ko EK, Koo SG, Koo JW, Kwon KH, Kwon SH, et al. Nasopharyngeal carcinoma. In: Kim SY. Otorhinolaryngololgy Head and Neck Surgery. Seoul, Korea: Iljokak. 2013. p1649-1656.
  2. Spiro RH, Huvos AG, Berk R, Strong EW. Mucoepidermoid carcinoma of salivary gland origin. A clinicopathologic study of 367 cases. Am J Surg. 1978;136:461-468. https://doi.org/10.1016/0002-9610(78)90262-3
  3. Garden AS, RS Weber, Ang KK, Morrison WH, Matre J, Peters LJ. Postoperative radiation therapy for malignant tumors of minor salivary glands. Cancer. 1985;73:2563-2569.
  4. Hicks J, Flaitz C. Mucoepidermoid carcinoma of salivary glands in children and adolescents: Assesement of proliferation markers. Oral Oncol. 2000;36:454-460. https://doi.org/10.1016/S1368-8375(00)00033-6
  5. Pires FR, Almeida OP, Araujo VC, Kowalski LP. Prognostic factors in head and neck mucoepidermoid carcinoma. Arch Otolaryngol Head Neck Surg. 2004;130:174-180. https://doi.org/10.1001/archotol.130.2.174
  6. Anderson JN, Beenken SW, Crowe R, Soong SJ, Peters G, Maddox WA, et al. Prognostic factors in minor salivary gland cancer. Head Neck. 1995;17:480-486. https://doi.org/10.1002/hed.2880170605
  7. Tseng-tong K, Ngan-Ming T. Salivary gland type nasopharyngeal carcinoma. Am J Surg. 2001;25:80-86.
  8. Kuo TT, Tsang NM. Salivary gland type nasopharyngeal carcinoma: histologic, immunohistochemical, and Epstein-Barr virus study of 15 cases including a psammomatous mucoepidermoid carcinoma. Am J Surg Pathol 2001;25:80-86. https://doi.org/10.1097/00000478-200101000-00009
  9. Re M, Paquini E. Nasopharyngeal mucoepidermoid carcinoma in children. Int J Pediatr Otorhinolaryngol. 2013;77:565-569. https://doi.org/10.1016/j.ijporl.2012.12.012