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A Case Report of Mucinous Adenocarcinoma of the Oral Tongue

구강설에 발생한 점액선암종 1예

  • Kang, Ju Yong (Department of Otorhinolaryngology-Head and Neck Surgery, Korea Cancer Center Hospital) ;
  • Choi, Ik Joon (Department of Otorhinolaryngology-Head and Neck Surgery, Korea Cancer Center Hospital) ;
  • Lee, Byeong Cheol (Department of Otorhinolaryngology-Head and Neck Surgery, Korea Cancer Center Hospital)
  • 강주용 (한국원자력의학원 원자력병원 이비인후-두경부외과) ;
  • 최익준 (한국원자력의학원 원자력병원 이비인후-두경부외과) ;
  • 이병철 (한국원자력의학원 원자력병원 이비인후-두경부외과)
  • Received : 2017.09.05
  • Accepted : 2018.10.18
  • Published : 2018.11.30

Abstract

Mucinous adenocarcinoma (MAC) is a rare malignant neoplasm that occasionally occurs in the large intestine (colon), followed by the pancreas, ovary, lung, prostate, and breast. It is characterized by large amounts of extracellular epithelial mucin that contains tumor cell nests. We herein present a unique case of MAC originating from minor salivary gland, the second to be reported in literature in South Korea. We report a case of MAC in the tongue considered to be developed from minor salivary gland with a review of literature.

Keywords

References

  1. Ellis GL, Auclair PL. Tumors of the salivary glands. Atlas of tumor pathology, 3rd series, Fascicle 17. Washington DC: Armed Forces Institute of Pathology; 1996. p.349-52.
  2. Tokio O, Jyusui H, Akihiko Ohno, Yukihiro T. Mucinous adenocarcinoma of the submandibular gland. Cancer. 1990;66:1796-801. https://doi.org/10.1002/1097-0142(19901015)66:8<1796::AID-CNCR2820660826>3.0.CO;2-K
  3. Krogdahl AS, Schou C. Mucinous adenocarcinoma of the sublingual gland. J Oral Pathol Med. 1997;26:198-200. https://doi.org/10.1111/j.1600-0714.1997.tb00458.x
  4. Mezmezian M, Spreafico H, Glembocki A, Carassai M. Primary mucinous adenocarcinoma of minor salivary glands of the palate: Case report and literature review. J Oral Maxillofac Surg. 2015;27;446-9.
  5. Uchida K, Oga A, Mano T, et al. Screening for DNA copy number aberrations in mucinous adenocarcinoma arising from the minor salivary gland: two case reports. Cancer Genet Cytogenet. 2010;203:324-7. https://doi.org/10.1016/j.cancergencyto.2010.08.027
  6. Ken-ichi N, Tadashi I, Yutaka Y, Tohru H, Chihiro S, Takao K, et al. Mucinous adenocarcinoma of probable minor salivary gland origin. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002; 94:738-40. https://doi.org/10.1067/moe.2002.126698
  7. Yoo WJ, Kim JS, Lee HY, Lee SY. A Case of Mucinous Adenocarcinoma of the Parotid Gland. Korean J Otolaryngol. 1999;42:1326-8.
  8. Yakirevich E, Sabo E, Klorin G, Alos L, Cardesa A, Ellis G, et al. Primarymucin-producing tumours of the salivary glands: a clinicopathological and morphometric study. Histopathology. 2010;57:395-409. https://doi.org/10.1111/j.1365-2559.2010.03639.x
  9. Ide F, Mishima K, Tanaka A, Saito I, Kusama K. Mucinous adenocarcinoma of minor salivary glands: a high-grade malignancy prone to lymph node metastasis. Virchows Arch. 2009;454:55-60. https://doi.org/10.1007/s00428-008-0699-1
  10. Pawelec GW, Koryczan P, Zapala J, Gontarz M, Opach M, Kusnierz P, et al. Minor salivary gland mucinous adenocarcinoma of buccal mucosa-Case report and review and review of literature. POL J PATHOL. 2013;64(4):312-16.
  11. Krogdahl AS, Schou C. Mucinous adenocarcinoma of the sublingual gland. J Oral Pathol Med. 1997;26:198-200. https://doi.org/10.1111/j.1600-0714.1997.tb00458.x