Journal of Fashion Business (패션비즈니스)

The Korean Society of Fashion Business (한국패션비즈니스학회)
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Stability Determination of the Various Cosmetic Formulations containing Glycolic Acid

  • Received : 2018.05.19
  • Accepted : 2018.07.20
  • Published : 2018.07.30
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Abstract

Glycolic acid(GA) is well known the most effective cosmetic ingredient on the epidermal remodeling, accelerated desquamation and inhibitory effect on melanin synthesis. The various cosmetic formulations containing GA have not been reported in terms of stability. This study was to investigate the stability of three formulations(gel, cream, and ointment). The stability of obtained formulations was tested chemical and physical characteristics including the composition stability, hot-cool cycling, the variation of pH and viscosity, and the observation of color and odor. The experimental results showed that the gel and cream containing 5% GA, both formulations have proper stability in the centrifugal test, hot-cool cycling test, viscosity, pH stability and the observation of color and odor. On the other hand, the 5% GA ointment did not have stability. We concluded that the formulations of gel and cream are more suitable than ointment to use GA ingredient for developing cosmetic in terms of stability.

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References

  1. Alina lliescu C. (2005). Investigation on the thermal stability of technical and cosmetic emulsions. (Unpublished Doctoral dissertation) RWTH Aachen University, Achen, Germany
  2. Campos P., Gaspar L. R., Goncalves G., Pereira L., Semprini M., Lopes R. A. (2015) Comparative Effects of Retinoic Acid or Glycolic Acid Vehiculated in Different Topical Formulations. BioMed Research International, 2015, 1-6
  3. Couch L. H., Howard P. C. (2002). Quantification of glycolic acid in cosmetic products using reversed phase high performance liquid chromatography. Journal of Cosmetic Science, 24, 89-95 https://doi.org/10.1046/j.1467-2494.2002.00128.x
  4. Dal’Belo S. E., Gaspar L. R., Berardo P. M., Campos G. M. (2006). Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. Skin Research and Technology, 12(4), 241-6 https://doi.org/10.1111/j.0909-752X.2006.00155.x
  5. Ditre CM. (1998). Building your practice with glycolic acid peels. Skin Aging, 6, 48-53.
  6. Fartasch M, Teal J, Menon GK. (1997). Mode of action of glycolic acid on human stratum corneum. Archives of Dermatolgical Research, 289, 404-409. https://doi.org/10.1007/s004030050212
  7. Faria W., Damasceno G., Ferrari M. (2014). Moisturizing effect of a cosmetic formulation containing pequi oil (Caryocar brasiliense) from the Brazilian cerrado biome. Brazilian Journal of Pharmaceutical Sciences, 50(1), 131-136 https://doi.org/10.1590/S1984-82502011000100013
  8. FDC legislation. (2011). Assurance of Cosmetics Among Europe. USA and Republic of Korea, 6(1) 19-28
  9. John, S. (1985). Fundamentals of stability testing. International Journal of Cosmetic Science, 7, 291-303. https://doi.org/10.1111/j.1467-2494.1985.tb00423.x
  10. Ju J. (2017). Effects of rhEGF and Palmitoyl pentapeptide-4 for skin regeneratin after glycolic acid peeling, (Unpublished Master's thesis). Wonkwang university, Iksan, Korea.
  11. Kornhauser A., Coelho S. G., Hearing W. J. (2012). Effects of Cosmetic Formulations Containing Hydroxyacids on Sun-Exposed Skin: Current Applications and Future Developments. Dermatology Research and Practice, 2012, 1-6
  12. Mukherjee S., Habif S., Rick D. (1999). Stable cosmetic conpositions with different pH emulsions. Partent No. US 5935589 A
  13. Narayanan M., Sekar P., Pasupathi M., Mukhopadhyay T. (2017). Self-preserving personal care products. International Journal of Cosmetic Science, 39(3), 301-309 https://doi.org/10.1111/ics.12376
  14. Olejnik A., Goscianska J., Zielnska A., Nowak I. (2015). Stability determination of the formulations containing hyaluronic acid. International Journal of Cosmetic Science, 37(4), 401-407 https://doi.org/10.1111/ics.12210
  15. Ruiz M. A., Clares B., Morales M. E., Cazalla S., Gallardo V. (2007). Preparation and stability of cosmetic formulations with an anti-aging peptide. Journal of Cosmetic Science, 58(2), 157-171
  16. U.S. Food & Drug Administration. Labeling for Topically Applied Cosmetic products containing alpha hydroxy acids as ingredients (2005). Guidance for industry https://www.fda.gov/