Clinical Endoscopy

The Korean Society of Gastrointestinal Endoscopy (대한소화기내시경학회)
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Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm

  • Lee, Hyun Jik (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Lee, Yoo Jin (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Lee, Ju Yup (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Kim, Eun Soo (Department of Internal Medicine, Kyungpook National University School of Medicine) ;
  • Chung, Woo Jin (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Jang, Byoung Kuk (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Park, Kyung Sik (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Hwang, Jae Seok (Department of Internal Medicine, Keimyung University School of Medicine) ;
  • Cho, Kwang Bum (Department of Internal Medicine, Keimyung University School of Medicine)
  • Received : 2017.07.06
  • Accepted : 2017.09.17
  • Published : 2018.05.30
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Abstract

Background/Aims: Endoscopic submucosal dissection (ESD) has been widely accepted as a method of treatment of early gastric tumor. This study aimed to identify the incidence and characteristics of multiple gastric tumors after ESD. Methods: Patients with early gastric tumors who were treated by ESD from January 2004 to June 2012 and followed up with endoscopic examination periodically for at least 1 year were enrolled. All multiple gastric lesions were subsequently treated with ESD and the medical records of the patients were retrospectively reviewed. Results: In total, 643 patients were included. The mean duration of endoscopic follow-up was $45.27{\pm}27.59$ (range, 12-148) months. Overall, 144 patients (22.4%) showed multiple gastric tumors during the follow-up period (44 synchronous [6.8%] and 100 metachronous [15.5%]). The cumulative incidence rate steadily increased during the follow-up period. More than 50% of the tumors that developed at the same longitudinal location of the stomach were of the same macroscopic and histological type as the primary lesions. Conclusions: Because synchronous and/or metachronous gastric tumors are common, considerable attention should be paid to detect multiple gastric lesions after ESD of early gastric neoplasm.

Keywords

References

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