Clinical and Experimental Vaccine Research

  • 제7권1호
  • /
  • Pages.16-23
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  • 2018
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  • 2287-3651(pISSN)
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  • 2287-366X(eISSN)
대한백신학회 (The Korean Vaccine Society)
권호 표지
DOI QR코드

DOI QR Code

Distinct features of dendritic cell-based immunotherapy as cancer vaccines

  • Lee, Chaelin (Department of Bioscience & Biotechnology, Sejong University) ;
  • Lee, Myungmi (Department of Bioscience & Biotechnology, Sejong University) ;
  • Rhee, Inmoo (Department of Bioscience & Biotechnology, Sejong University)
  • 투고 : 2017.11.25
  • 심사 : 2017.12.28
  • 발행 : 2018.01.31
⟨ 이전 논문 다음 논문 ⟩

초록

Dendritic cells (DCs) are the most professional antigen presenting cells that play important roles in connection between innate and adaptive immune responses. Numerous studies revealed that the functions of DCs are related with the capture and processing of antigen as well as the migration to lymphoid tissues for the presenting antigens to T cells. These unique features of DCs allow them to be considered as therapeutic vaccines that can induce immune responses and anti-tumor activity. Here, we discuss and understand the immunological basis of DCs and presume the possibilities of DC-based vaccines for the promising cancer therapy.

키워드

과제정보

연구 과제 주관 기관 : National Research Foundation of KOREA (NRF)

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