Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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A comparative study of the gamma-interferon assay and the single intradermal tuberculin test for the diagnosis of bovine tuberculosis under field conditions

소 결핵병 검사에 사용되는 감마인터페론법과 단일피내접종법의 상관관계 비교분석

  • Ha, Min-Jong (East-Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Oh, Gyeong-Min (East-Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Kim, Sang-Yun (East-Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Do, Jae-Cheul (West-Branch, Gyeongbuk Veterinary Service Laboratory) ;
  • Lee, Young-Ju (College of Veterinary Medicine, Kyungpook National University)
  • 하민종 (경상북도동물위생시험소 동부지소) ;
  • 오경민 (경상북도동물위생시험소 동부지소) ;
  • 김상윤 (경상북도동물위생시험소 동부지소) ;
  • 도재철 (경상북도동물위생시험소 서부지소) ;
  • 이영주 (경북대학교 수의과대학)
  • Received : 2017.12.29
  • Accepted : 2018.06.13
  • Published : 2018.06.30
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Abstract

Bovine tuberculosis (bTB) is a wide-spread zoonotic disease in cattle, which is casued by Mycobacterium bovis that is a part of Mycobacterium tuberculosis complex (MTC). This study describes a field trial conducted in 42 herds with the history of prevalence bovine tuberculosis. Two cell-mediated immunity tests, the gamma-interferon (${\gamma}-IFN$) assay and the single intradermal tuberculin test (SIT) were applied for the diagnosis of bovine tuberculosis in 5,289 animals. The ${\gamma}-IFN$ assay presented 144 (2.7%) head of cattle with the positive result, and 112 (2.1%) head of cattle were shown to be bTB-positive by the SIT. The positive concordance was 45.5%, and the negative concordance was 98.2%. The ${\gamma}-IFN$ assay showed more positive results in younger cattle, especially between 12 and 23 months of age. It is shown that the strategic combination of both cell-mediated immunity test methods is more efficient for the detection of bTB to reduce the number of false positive individuals which are being slaughtered.

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References

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