Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Determination of Silybin B in the Different Parts of Silybum marianum using HPLC-UV

  • Rodriguez, Joyce P. (Department of Integrative Plant Science, Chung-Ang University) ;
  • Quilantang, Norman G. (Department of Integrative Plant Science, Chung-Ang University) ;
  • Lee, Ju Sung (Department of Integrative Plant Science, Chung-Ang University) ;
  • Lee, Jeong Min (Natural Products Research Team, National Marine Biodiversity Institute of Korea) ;
  • Kim, Hyun Young (Department of Food Science, Gyeongnam National University of Science and Technology) ;
  • Shim, Jae Suk (Imsil Herbal Medicine Association) ;
  • Lee, Sanghyun (Department of Integrative Plant Science, Chung-Ang University)
  • Received : 2017.09.08
  • Accepted : 2017.12.22
  • Published : 2018.06.30
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Abstract

Silymarin is the standardized extract from Silybum marianum which consists mainly of flavonoids and polyphenols. It is highly regarded for its hepatoprotective ability. Silybin B is a flavonolignan and one of the active components of silymarin. The content of silybin B in various parts of S. marianum was analyzed by HPLC-UV. Results show that the extract of seeds contain the highest amount of silybin B (7.434 mg/g DW). The petioles of S. marianum showed a low content of silybin B. This study revealed that seeds of S. marianum contain high amount of silybin B and could be a good source of the compound.

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