The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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Review of Clinical Researches for Herbal Medicine Treatment on Nocturnal Enuresis in Children

소아 야뇨의 한약치료에 대한 임상연구 동향 -중의학 논문을 중심으로-

  • Shin, Hye Jin (Pediatrics of Clinical Korean Medicine, Graduate School, Kyung Hee University, Department of Pediatrics of Korean Medicine, Kyung Hee University Hospital at Gangdong) ;
  • Lee, Boram (Pediatrics of Clinical Korean Medicine, Graduate School, Kyung Hee University, Department of Pediatrics of Korean Medicine, Kyung Hee University Hospital at Gangdong) ;
  • Lee, Jihong (Pediatrics of Clinical Korean Medicine, Graduate School, Kyung Hee University, Department of Pediatrics of Korean Medicine, Kyung Hee University Hospital at Gangdong) ;
  • Chang, Gyu Tae (Pediatrics of Clinical Korean Medicine, Graduate School, Kyung Hee University, Department of Pediatrics of Korean Medicine, Kyung Hee University Hospital at Gangdong)
  • 신혜진 (경희대학교 대학원 임상한의학과 소아과학교실, 강동경희대학교병원 한방소아과) ;
  • 이보람 (경희대학교 대학원 임상한의학과 소아과학교실, 강동경희대학교병원 한방소아과) ;
  • 이지홍 (경희대학교 대학원 임상한의학과 소아과학교실, 강동경희대학교병원 한방소아과) ;
  • 장규태 (경희대학교 대학원 임상한의학과 소아과학교실, 강동경희대학교병원 한방소아과)
  • Received : 2018.04.26
  • Accepted : 2018.05.15
  • Published : 2018.05.31
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Abstract

Objectives The purpose of this study is to evaluate the efficacy and safety of herbal medication for the treatment of nocturnal enuresis in children by analyzing randomized controlled trials conducted in China. Methods We searched literatures from China National Knowledge Infrastructure published up to 19 January, 2018. Selected literatures were collected and analyzed in order of publication year, and then demographic information, treatment method, duration of illness, duration of treatment, follow-up period, outcome measurement and adverse events. Results A total of 34 studies were selected for the analysis. In most studies, the total efficacy of the treatment group was reported to be higher than that of the control group, and the recurrence rate and complete cure rate were also found to be more effective in the herbal medicine treatment group. The most frequently used medical herb was Alpiniae Fructus (益智仁), and the use of medical herbs belong to tonifying yang (補陽藥), tonifying qi (補氣藥), and astringing essence strengthening collapse medicine (澁精縮尿止帶藥) were relatively high. The adverse events rate for the herbal medicine treatment group were significantly lower than those in the Western medicine treatment group. Conclusions This study showed that a herbal medicine treatment can be effective and safe option for treating pediatric nocturnal enuresis. However, additional well-designed clinical studies need to be performed to establish a basis.

Keywords

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