Korean Journal of Radiology

  • 제19권1호
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  • Pages.79-84
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  • 2018
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  • 1229-6929(pISSN)
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  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
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Diffusion-Weighted MR Imaging of Unicystic Odontogenic Tumors for Differentiation of Unicystic Ameloblastomas from Keratocystic Odontogenic Tumors

  • Han, Yifeng (Department of Interventional Radiology, Ninth People's Hospital, Shanghai Jiao Tong University) ;
  • Fan, Xindong (Department of Interventional Radiology, Ninth People's Hospital, Shanghai Jiao Tong University) ;
  • Su, Lixin (Department of Oral & Maxillofacial Surgery, Ninth People's Hospital, Shanghai Jiao Tong University) ;
  • Wang, Zhenfeng (Department of Interventional Radiology, Ninth People's Hospital, Shanghai Jiao Tong University)
  • 투고 : 2016.10.01
  • 심사 : 2017.01.27
  • 발행 : 2018.02.01
⟨ 이전 논문 다음 논문 ⟩

초록

Objective: Differentiating unicystic ameloblastomas from keratocystic odontogenic tumors (KCOT) is necessary for the planning of different treatment strategies; however, it is difficult based on conventional CT and MR sequences alone. The purpose of this study was to investigate the utility of diffusion-weighted imaging (DWI) and apparent diffusion coefficients (ADCs) in the differentiation of the two tumors. Materials and Methods: We prospectively studied 40 patients with odontogenic cysts and tumors of the maxillomandibular region using conventional MR imaging and DWI. ADCs were measured using 2 b factors (500 and 1000). Results: Unicystic ameloblastomas (n = 11) showed free diffusion on DWI and a mean ADC value of $2.309{\pm}0.17{\times}10^{-3}mm^2/s$. KCOT (n = 15) showed restricted diffusion on DWI with a mean ADC value of $0.923{\pm}0.20{\times}10^{-3}mm^2/s$ The ADC values of unicystic ameloblastomas were significantly higher than those of KCOT (p < 0.001, Mann-Whitney U-test). An ADC cut-off value of $2.0{\times}10^{-3}mm^2/s$ to differentiate KCOT and unicystic ameloblastomas resulted in a 100% sensitivity and 100% specificity. Dentigerous cysts (n = 3) showed restricted diffusion on DWI and similar ADC values ($1.257{\pm}0.05{\times}10^{-3}mm^2/s$) to those of KCOT. Conclusion: Diffusion-weighted imaging and ADC determination can be used as an adjuvant tool to differentiate between unicystic ameloblastomas and KCOT, although the ADC values of dentigerous cysts overlap with those of KCOT.

키워드

참고문헌

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  1. Odontogene Keratozyste - Ätiologie, Pathogenese und Therapie vol.13, pp.2, 2018, https://doi.org/10.1007/s11838-019-0082-x
  2. Three-dimensional radiographic features of ameloblastoma and cystic lesions in the maxilla vol.48, pp.6, 2018, https://doi.org/10.1259/dmfr.20190066
  3. Characteristics of Recent Articles Published in the Korean Journal of Radiology Based on the Citation Frequency vol.21, pp.12, 2020, https://doi.org/10.3348/kjr.2020.1322
  4. Usefulness of MR imaging for odontogenic tumors vol.109, pp.1, 2018, https://doi.org/10.1007/s10266-020-00559-z
  5. Differentiation of cystic lesions in the jaw by conventional magnetic resonance imaging and diffusion-weighted imaging vol.51, pp.1, 2018, https://doi.org/10.1259/dmfr.20210212