Clinical Endoscopy

  • 제51권1호
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  • Pages.80-88
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  • 2018
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  • 2234-2400(pISSN)
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  • 2234-2443(eISSN)
대한소화기내시경학회 (The Korean Society of Gastrointestinal Endoscopy)
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Clinical Value of Contrast-Enhanced Harmonic Endoscopic Ultrasonography in the Differential Diagnosis of Pancreatic and Gallbladder Masses

  • Leem, Galam (Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Chung, Moon Jae (Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Park, Jeong Youp (Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Bang, Seungmin (Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Song, Si Young (Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Chung, Jae Bock (Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Park, Seung Woo (Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine)
  • 투고 : 2017.03.13
  • 심사 : 2017.07.06
  • 발행 : 2018.01.30
⟨ 이전 논문 다음 논문 ⟩

초록

Background/Aims: Recent studies have revealed that contrast-enhanced harmonic endoscopic ultrasonography (CEH-EUS) is beneficial in the differential diagnosis of malignant neoplasms of the pancreas and gallbladder from benign masses, in terms of the evaluation of microvasculature and real-time perfusion. In this study, we aimed to prove the clinical value of CEH-EUS in the differential diagnosis of pancreatic and gallbladder masses by direct comparison with that of conventional EUS. Methods: We reviewed the sonographic images and medical information of 471 patients who underwent conventional EUS and CEH-EUS for the diagnosis of pancreatic and gallbladder masses at a single medical center (Severance Hospital, Seoul, Korea) between March 2010 and March 2016. Results: The enhancement pattern of CEH-EUS of the pancreatic solid masses showed higher sensitivity and specificity in differentiating pancreatic adenocarcinoma and neuroendocrine tumors (82.0% and 87.9% for pancreatic adenocarcinoma and 81.1% and 90.9% for neuroendocrine tumors, respectively), and the area under the receiver operating characteristic curves was higher than that of conventional EUS. The enhancement texture of CEH-EUS of the gallbladder masses showed a higher sensitivity in differentiating malignant masses than that of conventional EUS; however, the difference between the areas under the receiver operating characteristic curves was not statistically significant. Conclusions: CEH-EUS can complement conventional EUS in the diagnosis of pancreatic and gallbladder masses, in terms of the limitations of the latter.

키워드

참고문헌

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  14. The Role of Endoscopic Ultrasound in the Diagnosis of Gallbladder Lesions vol.11, pp.10, 2018, https://doi.org/10.3390/diagnostics11101789
  15. A simple method for diagnosing gallbladder malignant tumors with subserosa invasion by endoscopic ultrasonography vol.21, pp.1, 2018, https://doi.org/10.1186/s12885-021-08017-x