The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Type 2 Autoimmune Pancreatitis with Ulcerative Colitis Manifesting as Acute Pancreatitis

급성췌장염 양상을 보였던 궤양성대장염을 동반한 2형 자가면역췌장염

  • Kim, Ha Il (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Chung, Hye Min (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Jung Hwan (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Noh, Soo Min (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Hsing, Li Chang (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Myung-Hwan (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 김하일 (울산대학교 의과대학 서울아산병원 내과) ;
  • 정혜민 (울산대학교 의과대학 서울아산병원 내과) ;
  • 이정환 (울산대학교 의과대학 서울아산병원 내과) ;
  • 노수민 (울산대학교 의과대학 서울아산병원 내과) ;
  • 형례창 (울산대학교 의과대학 서울아산병원 내과) ;
  • 김명환 (울산대학교 의과대학 서울아산병원 내과)
  • Received : 2017.05.30
  • Accepted : 2017.06.28
  • Published : 2018.04.01
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Abstract

Autoimmune pancreatitis (AIP) occurs in two forms. Type 1 AIP is an IgG4-related systemic fibro-inflammatory disease. Type 2 AIP is not associated with altered levels of IgG4, and involves only the pancreas. Here, we report a case of type 2 AIP manifesting as acute pancreatitis in a 20-year-old male with ulcerative colitis. The patient was definitely diagnosed with type 2 AIP based on typical pancreatic imaging, supportive histology, history of ulcerative colitis, and steroid responsiveness.

2형 자가면역췌장염은 급성췌장염의 임상 양상으로 발현 할 수 있다. 특히 젊은 환자에서 원인미상의 췌장염으로 확인된 경우, 췌장 영상 소견을 특히 주의 깊게 관찰하여 이미 알려진 자가면역췌장염 소견과 합당한지 따져보는 것이 중요하다. 특히 궤양성대장염 환자에서 췌장염이 동반되는 경우, 한 번쯤은 2형 자가면역췌장염의 동반 유무를 감별해 보아야 할 것이다. 이와 같은 경우라면 췌장 조직 검사를 적극적으로 시행함으로서 자가면역췌장염을 진단할 수 있겠고, 스테로이드 투여를 통해 효과적으로 치료를 기대해 볼 수 있겠다.

Keywords

References

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